Sponsor Pipeline

Roche / Genentech Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-26
252
Active Trials
113
Recruiting
88
Phase 3
10
Disease Areas
96
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-25 NCT02838420
A Study to Evaluate and Compare the Efficacy and Safety of Alectinib Versus Crizotinib…
Trial completed
2026-06-25 NCT02838420
A Study to Evaluate and Compare the Efficacy and Safety of Alectinib Versus Crizotinib…
date change Completion moved earlier: 2026-06-30 -> 2026-05-11
2026-06-24 NCT05910528
Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease
date change Primary completion moved earlier: 2030-12-31 -> 2026-12-31
2026-06-24 NCT05910528
Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease
date change Completion moved earlier: 2030-12-31 -> 2026-12-31
2026-06-24 NCT07054190
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated…
Trial arms changed: 3 -> 4
2026-06-24 NCT07054190
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated…
Trial sites expanded: 30 -> 33 locations
2026-06-24 NCT07558915
A Study to Evaluate RO7851624 in Participants With Relapsed/Refractory Multiple Myeloma…
Recruitment opened
2026-06-24 NCT07282574
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of…
Trial sites expanded: 73 -> 91 locations
2026-06-24 NCT07351045
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With…
Trial sites expanded: 73 -> 128 locations
2026-06-24 NCT04777331
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants…
date change Completion pushed: 2026-12-30 -> 2031-06-30
2026-06-24 NCT06850922
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603…
Trial completed
2026-06-24 NCT06850922
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603…
Enrollment reduced: 546 -> 388 participants
2026-06-24 NCT06850922
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603…
date change Primary completion moved earlier: 2027-04-30 -> 2026-05-19
2026-06-24 NCT06850922
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603…
date change Completion moved earlier: 2027-04-30 -> 2026-06-19
2026-06-24 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
Trial sites expanded: 4 -> 7 locations
2026-06-24 NCT07351058
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With…
Trial sites expanded: 61 -> 122 locations
2026-06-23 NCT07059273
A COPD Data Registry for Participants With Frequent Exacerbations
overall status: "Not Yet Recruiting" → "Withdrawn"
2026-06-23 NCT07059273
A COPD Data Registry for Participants With Frequent Exacerbations
Enrollment reduced: 3000 -> 0 participants
2026-06-23 NCT05808764
A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With…
Trial completed
2026-06-23 NCT05808764
A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With…
Enrollment increased: 10 -> 11 participants
Showing 20 of 96 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-25 NCT07667322 A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and… Phase 1 Recruiting
2026-06-24 NCT07665723 An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's… Phase 1 Recruiting
2026-06-12 NCT07643831 Expanded Access Program to Provide Giredestrant to Participants With ER+, HER2- Early or… Available
2026-06-05 NCT07629583 To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus… Phase 1 Not Yet Recruiting
2026-06-04 NCT07626515 A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in… Phase 1 Not Yet Recruiting
2026-06-02 NCT07620392 An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants… Phase 2 Not Yet Recruiting
2026-06-01 NCT07617337 AQUA07 in Patients With ALK-Positive Non-Small Cell Lung Cancer Phase 1 Not Yet Recruiting
2026-05-27 NCT07609719 A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple… Phase 4 Not Yet Recruiting
Active Trials by Phase
Phase 4
11
Phase 3
84
Phase 2/3
4
Phase 2
51
Phase 1/2
26
Phase 1
53
Not specified
23
Active Trials — top 25 of 252
NCT IDTitleConditionStatus
Phase 4
NCT05861986 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early… Muscular Atrophy, Spinal Recruiting
NCT07483450 A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of… Relapsing Multiple Sclerosis Recruiting
NCT06274515 A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies Breast Cancer Recruiting
NCT05861999 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric… Muscular Atrophy, Spinal Recruiting
NCT04853251 A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related… Neovascular Age-related Macular Degeneration Recruiting
NCT05232929 Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA) Spinal Muscular Atrophy Active, Not Recruiting
NCT05181618 A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants… Severe Hemophilia A Active, Not Recruiting
NCT06795048 A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants… Neovascular Age-related Macular Degeneration (nAMD) Active, Not Recruiting
NCT07025811 A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants… Dry Eye Disease Active, Not Recruiting
NCT05224102 A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented… Diabetic Macular Edema Active, Not Recruiting
NCT07609719 A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple… Multiple Sclerosis Not Yet Recruiting
Phase 3
NCT06675955 An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and… Multiple Sclerosis Recruiting
NCT06094010 A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants… Influenza Recruiting
NCT05894239 A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo… Metastatic Breast Cancer Recruiting
NCT05878769 A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic… Chronic Obstructive Pulmonary Disease Recruiting
NCT06084936 A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in… Lymphoma Recruiting
NCT06588855 A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also… Moderately to Severely Active Ulcerative Colitis Recruiting
NCT06790693 A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and… Breast Cancer Recruiting
NCT06819878 A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With… Moderately to Severely Active Crohns Disease Recruiting
NCT07169578 A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease Alzheimers Disease Recruiting
NCT03683251 Extension Study for the Port Delivery System With Ranibizumab (Portal) Neovascular Age-Related Macular Degeneration Recruiting
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a… Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Recruiting
NCT07174310 A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in… Parkinson's Disease Recruiting
NCT07177352 Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's… Alzheimers Disease Recruiting
NCT05503264 A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics… NMDAR Autoimmune Encephalitis Recruiting
View all 252 active Roche / Genentech trials with filters →
Disease Areas
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