NRG Oncology clinical trial pipeline

7 trials changed in the last 30 days: 0 stopped, 0 with notable changes, 7 with minor changes only.

1. Minor

   Observation or Radiation Therapy · Newly Diagnosed Grade II…Observation or Radiation Therapy · Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

   Enrollment closed, study ongoing

   NRG Oncology·Phase 3· NCT03180268· Registry history of NCT03180268 on ClinicalTrials.gov (opens the registry)

   Updated Oct 2, 2026

2. Minor

   Longer Duration Radiation Therapy Versus the Usual Radiation…Longer Duration Radiation Therapy Versus the Usual Radiation Therapy · Cancer That Has Spread to the Brain

   Enrollment closed, study ongoing

   NRG Oncology·Phase 3· NCT06500455· Registry history of NCT06500455 on ClinicalTrials.gov (opens the registry)

   Updated Sep 14, 2026

3. Minor

   If High Dose Radiation Only to the Sites of Brain Cancer Compared…If High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

   Enrollment closed, study ongoing

   Also in this update: Final enrollment: 152 participants (planned 200)

   NRG Oncology·Phase 3· NCT04804644· Registry history of NCT04804644 on ClinicalTrials.gov (opens the registry)

   Updated Sep 14, 2026

4. Minor

   Antiandrogen Therapy and Radiation Therapy With or Without…Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel · Prostate Cancer That Has Been Removed by Surgery

   Sponsor refiled this as active, not recruiting (was completed)

   NRG Oncology·Phase 2/3· NCT03070886· Registry history of NCT03070886 on ClinicalTrials.gov (opens the registry)

   Updated Sep 14, 2026

5. Minor

   Radiation Therapy With or Without Apalutamide · Recurrent Prostate…Radiation Therapy With or Without Apalutamide · Recurrent Prostate Cancer, the BALANCE Trial

   Completion pushed from Oct 27, 2026 to Mar 10, 2030

   NRG Oncology·Phase 2· NCT03371719· Registry history of NCT03371719 on ClinicalTrials.gov (opens the registry)

   Updated Oct 1, 2026

6. Minor

   Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy…Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide · Newly Diagnosed Glioblastoma

   Completion pushed from Dec 31, 2026 to Jul 7, 2030

   NRG Oncology·Phase 2· NCT02179086· Registry history of NCT02179086 on ClinicalTrials.gov (opens the registry)

   Updated Oct 1, 2026

7. Minor

   Addition of the Anti-cancer Viral Therapy Telomelysin™ to…Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation · Advanced Esophageal Cancer and Are Not Candidates for Surgery

   Completion moved earlier from Oct 6, 2030 to Oct 6, 2029

   NRG Oncology·Phase 1· NCT04391049· Registry history of NCT04391049 on ClinicalTrials.gov (opens the registry)

   Updated Oct 1, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.