Sponsor Pipeline

Roche / Genentech Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
251
Active Trials
104
Recruiting
89
Phase 3
10
Disease Areas
129
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-15 NCT07351058
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With…
Trial sites expanded: 163 -> 193 locations
2026-08-15 NCT07239336
Study of DONQ52 in Active Celiac Disease
Trial sites expanded: 70 -> 74 locations
2026-08-15 NCT05878769
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic…
Enrollment closed, study ongoing
2026-08-15 NCT05878769
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic…
Trial sites reduced: 486 -> 481 locations
2026-08-15 NCT05878769
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic…
date change Primary completion moved earlier: 2034-07-01 -> 2027-06-30
2026-08-15 NCT05878769
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic…
date change Completion moved earlier: 2034-07-01 -> 2027-06-30
2026-08-15 NCT05797610
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants…
Enrollment closed, study ongoing
2026-08-15 NCT05797610
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants…
Trial sites reduced: 204 -> 178 locations
2026-08-15 NCT07351045
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With…
Trial sites expanded: 164 -> 195 locations
2026-08-15 NCT07158242
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121)…
Trial sites expanded: 15 -> 22 locations
2026-08-15 NCT04774718
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric…
Enrollment closed, study ongoing
2026-08-15 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
Trial sites expanded: 15 -> 40 locations
2026-08-15 NCT04567303
Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration
date change Primary completion pushed: 2026-03-10 -> 2026-08-25
2026-08-14 NCT04603807
A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants…
date change Primary completion moved earlier: 2028-06-26 -> 2026-09-30
2026-08-14 NCT04603807
A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants…
date change Completion moved earlier: 2028-06-26 -> 2028-01-29
2026-08-14 NCT07670416
A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or…
Trial sites expanded: 12 -> 18 locations
2026-08-14 NCT03782207
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions…
Trial completed
2026-08-14 NCT07667322
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and…
Enrollment closed, study ongoing
2026-08-14 NCT04567303
Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration
date change Primary completion moved earlier: 2026-08-01 -> 2026-03-10
2026-08-14 NCT05872763
A Study of Participants in China With Non-Small-Cell Lung Cancer That is Unable to be…
Trial completed
Showing 20 of 129 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-08-06 NCT07749157 A Study of Subcutaneously Administered RO7845860 in Participants With Relapsing Multiple… Phase 1 Not Yet Recruiting
2026-08-05 NCT07748208 A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib… Phase 2 Not Yet Recruiting
2026-08-03 NCT07741604 A Study Investigating the Safety of RO7795081 and How the Body Processes RO7795081 in… Phase 1 Not Yet Recruiting
2026-07-21 NCT07717411 A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to… Phase 3 Not Yet Recruiting
Active Trials by Phase
Phase 4
10
Phase 3
85
Phase 2/3
4
Phase 2
52
Phase 1/2
27
Phase 1
53
Not specified
20
Active Trials — top 25 of 251
NCT IDTitleConditionStatus
Phase 4
NCT05861986 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early… Muscular Atrophy, Spinal Recruiting
NCT06274515 A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies Breast Cancer Recruiting
NCT04853251 A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related… Neovascular Age-related Macular Degeneration Recruiting
NCT05861999 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric… Muscular Atrophy, Spinal Recruiting
NCT07609719 A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple… Multiple Sclerosis Recruiting
NCT05224102 A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented… Diabetic Macular Edema Active, Not Recruiting
NCT07483450 A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of… Relapsing Multiple Sclerosis Active, Not Recruiting
NCT05232929 Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA) Spinal Muscular Atrophy Active, Not Recruiting
NCT05181618 A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants… Severe Hemophilia A Active, Not Recruiting
NCT06795048 A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants… Neovascular Age-related Macular Degeneration (nAMD) Active, Not Recruiting
Phase 3
NCT06675955 An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and… Multiple Sclerosis Recruiting
NCT06094010 A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants… Influenza Recruiting
NCT07541079 A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant… Early Breast Cancer Recruiting
NCT06819878 A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With… Moderately to Severely Active Crohns Disease Recruiting
NCT06847542 A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD Neovascular Age-related Macular Degeneration Recruiting
NCT07177352 Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's… Alzheimers Disease Recruiting
NCT05894239 A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo… Metastatic Breast Cancer Recruiting
NCT03683251 Extension Study for the Port Delivery System With Ranibizumab (Portal) Neovascular Age-Related Macular Degeneration Recruiting
NCT05562947 A Study of the Efficacy, Safety, and Pharmacokinetics (PK) of the Port Delivery System… Neovascular Age-related Macular Degeneration Recruiting
NCT06819891 A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart… Moderately to Severely Active Crohns Disease Recruiting
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a… Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Recruiting
NCT06084936 A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in… Lymphoma Recruiting
NCT06588855 A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also… Moderately to Severely Active Ulcerative Colitis Recruiting
NCT06790693 A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and… Breast Cancer Recruiting
NCT06793215 A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus… Non-Small Cell Lung Cancer Recruiting
See all 251 active Roche / Genentech trials with filters →
Disease Areas
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