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Children's National Research Institute clinical trial pipeline

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55 active trials 36 recruiting 18 disease areas 5 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-11

What changed in the last 30 days

2 trials changed in the last 30 days: 0 stopped, 1 with a notable change, 1 with a minor change only.

  1. Notable

    LIFT · Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion · Newly Diagnosed Diffuse Midline Glioma (LIFT)

    Recruitment opened

    Also in this update: Start date pushed from Sep 2026 to Oct 2026

    Children's National Research InstitutePhase 1 NCT07796061 Registry history of NCT07796061 on ClinicalTrials.gov (opens the registry)

    Updated

Show 1 trial with minor changes only
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-21 NCT07831018 Impact of AI Care Summaries on Caregiver Comprehension Recruiting
2026-09-21 NCT07832344 Unstuck-Early Childhood Effectiveness & Implementation Trial Not Yet Recruiting

Active trials by phase

Early Phase 1
1
Phase 1
10
Phase 2
6
Not charted: 38 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 55

NCT IDTitleConditionStatusUpdated
Phase 2
NCT06358638 Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With… Sickle Cell Disease Recruiting 2025-09-26
NCT05332067 Omalizumab Before Onset of Exacerbations Asthma in Children Recruiting 2025-07-14
NCT07784582 Pre-pubertal Low Dose Transdermal Estradiol in Turner Syndrome Turner Syndrome Not Yet Recruiting 2026-08-25
NCT02229968 Efficacy of Amicar for Children Having Craniofacial Surgery Craniosynostosis Active, Not Recruiting 2026-04-07
NCT04658771 MR-HIFU Treatment of Painful Osteoid Osteoma Osteoid Osteoma Active, Not Recruiting 2025-07-11
NCT05382637 Growth Hormone in a Patient With a Dominant-Negative GHR Mutation Growth Disorders Active, Not Recruiting 2025-07-02
Phase 1
NCT07796061 Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity… Pontine Diffuse Midline Glioma Recruiting 2026-10-07
NCT07664176 NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and… Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma Recruiting 2026-09-09
NCT07172958 Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory… Rhabdomyosarcoma Recruiting 2026-08-13
NCT05238792 Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk… Solid Tumor Recruiting 2026-08-04
NCT06193759 Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy… Medulloblastoma, Childhood Recruiting 2026-06-17
NCT05141058 T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients SARS-CoV-2 Infection Recruiting 2026-03-12
NCT04691622 Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised… Viral Infection Recruiting 2026-01-26
NCT06429982 Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols Rhabdomyolysis Recruiting 2025-07-03
NCT03180216 T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic… Viral Infections Active, Not Recruiting 2026-08-07
NCT02789228 Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of… Solid Tumors Active, Not Recruiting 2026-03-19
Early Phase 1
NCT07017816 A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With… CNS Malignancies Recruiting 2026-04-29
Not applicable
NCT07831018 Impact of AI Care Summaries on Caregiver Comprehension Health Literacy Recruiting 2026-09-21
NCT06036199 Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult… Cerebral Palsy, Dyskinetic Recruiting 2026-06-11
NCT04372875 Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A… Sexually Transmitted Diseases Recruiting 2026-03-18
NCT06623981 The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic Asthma in Children Recruiting 2026-02-24
NCT06224933 Augmented Reality For MRI-Guided Interventions Infections Recruiting 2025-09-05
NCT07115134 Efficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing Gastroenterology Surgery Recruiting 2025-08-11
NCT05488080 PAINED: Project Addressing INequities in the Emergency Department Pain Recruiting 2025-07-17
NCT06034678 Evaluation of The Food Allergy Mastery Program Food Allergy in Children Recruiting 2025-07-11

Disease areas by active trials, top 10 of 18

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