Children's Hospital of Philadelphia clinical trial pipeline

8 trials changed in the last 30 days: 0 stopped, 6 with notable changes, 2 with minor changes only.

1. Notable

   Validation of Nanosensor Oxygen Measurement

   Primary and study completion pushed from Sep 2026 to Sep 2027

   Also in this update: Enrollment reduced: 96 → 70 participants

   Children's Hospital of Philadelphia·Phase 1· NCT06819683· Registry history of NCT06819683 on ClinicalTrials.gov (opens the registry)

   Oct 7, 2026

2. Notable

   18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance…18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

   Primary completion pushed from Dec 2026 to Dec 2027

   Also in this update: Study completion pushed from Sep 2027 to Sep 2028

   Children's Hospital of Philadelphia·Early Phase 1· NCT05555550· Registry history of NCT05555550 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

3. Notable

   Molecular Basis of Food Allergy

   Primary completion pushed from Dec 2027 to Nov 2030

   Also in this update: Study completion pushed from Dec 2030 to Nov 2031

   Children's Hospital of Philadelphia·Not specified· NCT01832324· Registry history of NCT01832324 on ClinicalTrials.gov (opens the registry)

   Sep 21, 2026

4. Notable

   AB-CliniMACs · Allogeneic Stem Cell Transplant With Alpha/Beta T…AB-CliniMACs · Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies

   Primary endpoint(s) modified

   Also in this update: Phase changed: Phase 2 → not applicable; Results posted: Oct 6, 2026

   Children's Hospital of Philadelphia·Not applicable· NCT02323867· Registry history of NCT02323867 on ClinicalTrials.gov (opens the registry)

   Oct 6, 2026

5. Notable

   VATCH · 24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs

   Enrollment reopened

   Also in this update: Primary completion pushed from Aug 27, 2029 to Oct 27, 2029; Study completion pushed from Aug 27, 2030 to Oct 27, 2030

   Children's Hospital of Philadelphia·Phase 2· NCT07543822· Registry history of NCT07543822 on ClinicalTrials.gov (opens the registry)

   Oct 19, 2026

6. Notable

   VATCH · 24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs

   Enrollment reopened

   Also in this update: Primary completion pushed from Aug 27, 2029 to Oct 27, 2029; Study completion pushed from Aug 27, 2030 to Oct 27, 2030

   Children's Hospital of Philadelphia·Phase 2· NCT07549646· Registry history of NCT07549646 on ClinicalTrials.gov (opens the registry)

   Oct 19, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.