| Detected | Trial | Change |
|---|---|---|
| 2026-06-05 | NCT07581704 Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody… |
Recruitment opened |
| 2026-06-05 | NCT07581704 Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody… |
date change Primary completion pushed: 2029-05-01 -> 2029-06-01 |
| 2026-06-05 | NCT07581704 Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody… |
date change Completion pushed: 2029-09-01 -> 2029-10-01 |
| 2026-06-05 | NCT06872333 Allo HSCT for High Risk Hemoglobinopathies |
Trial arms changed: 4 -> 5 |
| 2026-05-23 | NCT06752694 Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-23 | NCT06752694 Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell… |
Enrollment reduced: 20 -> 1 participants |
| 2026-05-23 | NCT06752694 Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell… |
date change Primary completion moved earlier: 2027-12-31 -> 2026-01-23 |
| 2026-05-23 | NCT06752694 Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell… |
date change Completion moved earlier: 2027-12-31 -> 2026-10-15 |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-08 | NCT07634120 Vertebrobasilar Dolichoectasia Treatment With Sirolimus | Phase 2 | Not Yet Recruiting |
| 2026-06-01 | NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease | Phase 2 | Not Yet Recruiting |
| 2026-05-14 | NCT07587801 Vaccination Response Modulation With a Targeted Rapamycin Protocol Study | Phase 2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT05193565 | Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in… | Kidney Transplantation | Active, Not Recruiting |
| NCT07426484 | Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy | Cutaneous Squamous Cell Carcinoma | Not Yet Recruiting |
| NCT07542314 | Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Participants With Duchenne… | Duchenne Muscular Dystrophy | Not Yet Recruiting |
| Phase 3 | |||
| NCT07378657 | Systematic Approach for Children With Orbital Malformation With Sirolimus Use | Orbital Lymphatic Malformation | Recruiting |
| NCT04789070 | Phase III Trial of Sirolimus in IBM | Inclusion Body Myositis | Active, Not Recruiting |
| NCT07475546 | Combination Gerotherapeutic Interventions for Healthspan Improvement | Healthspan Improvement | Active, Not Recruiting |
| NCT00679042 | Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at… | Type 1 Diabetes Mellitus | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT07366801 | Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell… | Acute Myeloid Leukemia, Relapsed | Recruiting |
| Phase 2 | |||
| NCT05104983 | Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study | Tuberous Sclerosis Complex | Recruiting |
| NCT03121001 | Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive… | Sickle Cell Disease | Recruiting |
| NCT05237687 | The Role of Sirolimus in Preventing Functional Decline in Older Adults | Aging | Recruiting |
| NCT04469530 | Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid… | Solid Tumor | Recruiting |
| NCT04861064 | Weekly Sirolimus Therapy | Venous Malformation | Recruiting |
| NCT03970096 | Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant… | Acute Leukemia | Recruiting |
| NCT04141020 | Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms | Cerebral Aneurysm | Recruiting |
| NCT06261060 | Low-Dose Sirolimus to Increase Hematopoietic Function in Patients With RUNX1 Familial… | Familial Platelet Disorder | Recruiting |
| NCT03214354 | Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major… | Sickle Cell Disease | Recruiting |
| NCT04888741 | Methods of T Cell Depletion Trial (MoTD) | Acute Myeloid Leukemia | Recruiting |
| NCT02042326 | Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of… | Arteriovenous Malformations | Recruiting |
| NCT06055608 | Advancing Transplantation Outcomes in Children | Kidney Transplant | Recruiting |
| NCT03243019 | Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations | Lymphatic Malformation | Recruiting |
| NCT06872333 | Allo HSCT for High Risk Hemoglobinopathies | Graft Failure | Recruiting |
| NCT05836025 | Effect of Rapamycin in Ovarian Aging | Perimenopausal | Active, Not Recruiting |
| NCT03292861 | The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients | Heart Transplantation | Enrolling by Invitation |
| NCT02979873 | Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia… | Severe Aplastic Anemia | Active, Not Recruiting |