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Methods of T Cell Depletion Trial (MoTD)

Study acronym: MoTD
StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary and study completion dates: Jan 2026 to Aug 23, 2027
    • Study sites: 15 to 17
    • Collaborators: 1 to 2
    v4
  2. Primary and study completion dates: Jun 2025 to Jan 2026
    • Study sites: 1 to 15
    • Eligibility criteria expanded, about 8 words
    • Collaborators expanded, about 12 words
    v3
  3. Re-verified, no change to tracked fieldsv2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
University of Birmingham
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Leukemia
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Acute Myeloid Leukemia (AML)
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and 7 more diseases
A multi-centre phase II trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin vs. Calcineurin inhibitor or Sirolimus-based post-transplant cyclophosphamide.
Trial Details
NCT Number NCT04888741
Lead Sponsor University of Birmingham
Collaborators: The Jon Moulton Charity Trust, IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)
Conditions
(from sponsor)		 Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia +1 more
Related terms Hodgkin Disease, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis
Enrollment 400 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov