| Detected | Trial | Change |
|---|---|---|
| 2026-06-09 | NCT07386730 A Study of Psychedelics in Healthy Older Adults With Low Well-being |
Recruitment opened |
| 2026-06-06 | NCT05698511 Neural and Physiological Correlates of Psychedelic Sub-states |
date change Completion pushed: 2026-01-30 -> 2027-01-30 |
| 2026-06-05 | NCT05370911 Effects of Repeated Psilocybin Dosing in OCD |
date change Primary completion moved earlier: 2026-07 -> 2026-02-17 |
| 2026-06-05 | NCT05370911 Effects of Repeated Psilocybin Dosing in OCD |
date change Completion moved earlier: 2027-07 -> 2027-02 |
| 2026-06-02 | NCT06810310 Psilocybin on Brain Mechanisms of Motivation in OUD |
Sponsor changed: Anna Rose Childress, Ph.D. -> University of Pennsylvania |
| 2026-06-02 | NCT06810310 Psilocybin on Brain Mechanisms of Motivation in OUD |
date change Primary completion pushed: 2026-05-01 -> 2027-05-01 |
| 2026-06-02 | NCT06810310 Psilocybin on Brain Mechanisms of Motivation in OUD |
date change Completion pushed: 2026-05-01 -> 2027-05-01 |
| 2026-05-27 | NCT07435077 Examining Analgesic Synergy and Efficacy in Trauma Care |
date change Primary completion pushed: 2026-09 -> 2026-12 |
| 2026-05-27 | NCT07435077 Examining Analgesic Synergy and Efficacy in Trauma Care |
date change Completion pushed: 2026-09 -> 2026-12 |
| 2026-05-23 | NCT06230757 Psilocybin for Treatment-Resistant Depression |
Trial completed |
| 2026-05-23 | NCT06230757 Psilocybin for Treatment-Resistant Depression |
Enrollment reduced: 40 -> 20 participants |
| 2026-05-23 | NCT06230757 Psilocybin for Treatment-Resistant Depression |
date change Primary completion pushed: 2026-03-01 -> 2026-05-08 |
| 2026-05-23 | NCT06230757 Psilocybin for Treatment-Resistant Depression |
date change Completion pushed: 2026-03-01 -> 2026-05-08 |
| 2026-05-23 | NCT06768944 Subjective Experience Following Psilocybin |
Recruitment opened |
| 2026-05-23 | NCT06008990 Maternal Brain Imaging in Opioid Use Disorder |
Trial completed |
| 2026-05-23 | NCT06008990 Maternal Brain Imaging in Opioid Use Disorder |
Enrollment increased: 40 -> 45 participants |
| 2026-05-23 | NCT06008990 Maternal Brain Imaging in Opioid Use Disorder |
date change Primary completion moved earlier: 2026-04-01 -> 2025-10-31 |
| 2026-05-23 | NCT06008990 Maternal Brain Imaging in Opioid Use Disorder |
date change Completion moved earlier: 2026-07-31 -> 2025-10-31 |
| 2026-05-19 | NCT06299319 Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for… |
overall status: "Recruiting" → "Enrolling By Invitation" |
| 2026-05-16 | NCT06902974 Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD |
Enrollment increased: 35 -> 70 participants |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-10 | NCT07638553 Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive… | Phase 3 | Not Yet Recruiting |
| 2026-05-28 | NCT07610369 The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease | Phase 2 | Not Yet Recruiting |
| 2026-05-27 | NCT07607938 Psilocybin as a Novel Therapy for Residual Anhedonia | Phase 1 | Not Yet Recruiting |
| 2026-05-27 | NCT07610135 Psilocybin Efficacy With or Without Pimavanserin Pretreatment | Phase 1/2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT06323824 | Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid… | Opioid Use Disorder | Recruiting |
| NCT06880718 | Injectable Buprenorphine in Prison: A Preference Trial | Opioid Use Disorder | Recruiting |
| NCT07469501 | Comparing Outpatient Treatment Retention Among Individuals Using Fentanyl Randomized to… | Opioid Use Disorder | Not Yet Recruiting |
| NCT07176351 | Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile… | Opioid Use Disorder | Not Yet Recruiting |
| NCT07485335 | A Bundled Intervention to End Opioid Overdoses | Opioid Use Disorder | Not Yet Recruiting |
| NCT07435077 | Examining Analgesic Synergy and Efficacy in Trauma Care | Opioid Use Disorder | Not Yet Recruiting |
| Phase 3 | |||
| NCT07063862 | Psilocybin Microdose for Psychological and Existential Distress in Palliative Care… | Psychological Distress | Recruiting |
| NCT06494904 | Standard Versus High Dose ED-Initiated Buprenorphine Induction | Opioid Use Disorder | Recruiting |
| NCT05711940 | Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With… | Treatment Resistant Depression | Active, Not Recruiting |
| NCT06943573 | Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder | Bipolar II Depression | Not Yet Recruiting |
| NCT06303739 | Psilocybin-Assisted Therapy in Treatment-Resistant Depression | Refractory Depression | Active, Not Recruiting |
| NCT06308653 | Psilocybin for Major Depressive Disorder (MDD) | Depressive Disorder, Major | Active, Not Recruiting |
| NCT07226232 | Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression | Major Depression | Not Yet Recruiting |
| NCT07638553 | Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive… | Alcohol Use Disorder | Not Yet Recruiting |
| Phase 2 | |||
| NCT06888128 | State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for… | PTSD | Recruiting |
| NCT06796062 | Psilocybin for Opioid Use Disorder (OUD) | Opioid Use Disorder | Recruiting |
| NCT06399263 | Study of Psilocybin for Anorexia in Young Adults | Anorexia Nervosa | Recruiting |
| NCT07169747 | Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With… | Anorexia Nervosa | Recruiting |
| NCT06072898 | A Randomized Neuroimaging Trial of Psilocybin in Depression | Depressive Disorder | Recruiting |
| NCT06319378 | Cancer Related Major Depression Treated With a Single Dose of Psilocybin | MDD | Recruiting |
| NCT06200155 | Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy | Depression, Anxiety | Recruiting |
| NCT06801041 | TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted… | Depression | Recruiting |
| NCT05778591 | Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia | Schizophrenia | Recruiting |
| NCT07216404 | Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients… | Lung Non-Small Cell Carcinoma | Recruiting |
| NCT06902974 | Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD | Post Traumatic Stress Disorder | Recruiting |