Examining Analgesic Synergy and Efficacy in Trauma Care

Traumatic injury is responsible for over 25 million (16%) Emergency Department visits and over 225,000 deaths each year per 2021 Center for Disease Control data. This is the 3rd leading cause of death in the US. Often, acute care for the injured patient requires administration of pain medication for the purposes of acute pain control from injury. The mainstay of treatment for pain control has historically involved opioid pain medication.

NCT Number	NCT07435077
Lead Sponsor	Wake Forest University Health Sciences
Conditions	Opioid Use Disorder
Enrollment	282 participants
Start Date	2026-08
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-05-26