Clinical Trial

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

Name: Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression — clinical trial record (NCT07226232)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: PIVOT

Not Yet Recruiting Phase 3

View on ClinicalTrials.gov →

Summary

The purpose of this multi-site randomized controlled trial is to evaluate the efficacy and risks of psilocybin for the treatment of depression in U.S. military Veterans with and without (±) concurrent posttraumatic stress disorder.

Trial Details

NCT Number	NCT07226232
Lead Sponsor	VA Office of Research and Development
Conditions	Major Depression
Enrollment	240 participants
Start Date	2026-07-30
Primary Completion	2030-12-02 (estimated)
Study Completion	2031-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-05