| Detected | Trial | Change |
|---|---|---|
| 2026-06-03 | NCT07528508 A Clinical Trial in Healthy Participants to Study the Effect of a Single Dose of MK-8527… |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-05-19 | NCT07595263 A Study of Ulonivirine (MK-8507) and Methadone in Healthy Volunteers (MK-8507-019) | Phase 1 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT06525740 | Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic… | Malignant Female Reproductive System Neoplasm | Recruiting |
| NCT06962306 | Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery | Cleft Palate | Recruiting |
| NCT06784999 | Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head… | Free Flap Reconstruction | Recruiting |
| NCT06323824 | Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid… | Opioid Use Disorder | Recruiting |
| NCT07485803 | A RCT Using Methadone in the Management of Post-Operative Pain in Total Knee Replacement | Total Knee Arthroplasty | Not Yet Recruiting |
| NCT06868589 | Reducing Pain With Methadone and Ketamine in Liver Transplant | Liver Transplantation | Active, Not Recruiting |
| NCT07517679 | Methadone for Post-operative Spine Surgery | Pain, Postoperative | Not Yet Recruiting |
| NCT07546396 | Methadone Rapid Restart | Opioid Use Disorder | Not Yet Recruiting |
| Phase 3 | |||
| NCT07226076 | Methadone in TKA for Post-op Pain and Opioid Reduction | Post Operative Pain | Recruiting |
| NCT07227064 | Methadone in THA for Post-op Pain and Opioid Reduction | Post Operative Pain | Recruiting |
| NCT05417100 | Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for… | Spinal Surgery | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT05459402 | Divided or Single Exposure (DOSE) Study | Opioid Use Disorder | Recruiting |
| Phase 2 | |||
| NCT06536517 | The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in… | Fibroid Uterus | Recruiting |
| Phase 1 | |||
| NCT07528508 | A Clinical Trial in Healthy Participants to Study the Effect of a Single Dose of MK-8527… | Healthy | Recruiting |
| NCT07595263 | A Study of Ulonivirine (MK-8507) and Methadone in Healthy Volunteers (MK-8507-019) | Healthy | Not Yet Recruiting |
| Early Phase 1 | |||
| NCT06810336 | Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous… | Brain Injury | Recruiting |