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Methadone in the Management of Post-Operative Pain in Total Knee Replacement

StatusRecruiting
PhasePhase 4
Started
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Record History

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  1. Notable Recruitment openedv2 Show 4 more changesShow less
    • Study sites: 0 to 1
    • Start date changed from estimate of Jun 2026 to Jun 1, 2026
    • Secondary endpoints: details revised at 6 of 7 entries
    • Study title shortened, about 3 words
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
31 trials monitored
See 2 trials at risk
The goal of this study is to determine whether one dose of IV methadone given right before surgery will help patients' pain management after a total knee replacement and reduce the amount of pain medications taken in the weeks after surgery.
Trial Details
NCT Number NCT07485803
Lead Sponsor AdventHealth
Conditions
(from sponsor)
Total Knee Arthroplasty
Related terms Agnosia
Enrollment 192 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov