Clinical Trial

Methadone in the Management of Post-Operative Pain in Total Knee Replacement

Name: Methadone in the Management of Post-Operative Pain in Total Knee Replacement — clinical trial record (NCT07485803)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting Phase 4

View on ClinicalTrials.gov →

Summary

The goal of this study is to determine whether one dose of IV methadone given right before surgery will help patients' pain management after a total knee replacement and reduce the amount of pain medications taken in the weeks after surgery.

Protocol Amendment History 1 change

critical Recruitment opened 2026-06-23

Trial Details

NCT Number	NCT07485803
Lead Sponsor	AdventHealth
Conditions	Total Knee Arthroplasty
Enrollment	192 participants
Start Date	2026-06-01
Primary Completion	2028-04 (estimated)
Study Completion	2028-06 (estimated)
Updated on ClinicalTrials.gov	2026-06-22