Clinical Trial

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

Study acronym: OPAL-Cleft
Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-04-30; most recent amendment 2026-04-10.
Status change: Not Yet Recruiting → Recruiting 2025-05-23
Trial Details
NCT Number NCT06962306
Lead Sponsor Duke University
Conditions Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
Enrollment 60 participants
Start Date 2025-06-04
Primary Completion 2027-06-04 (estimated)
Study Completion 2027-07-04 (estimated)
Updated on ClinicalTrials.gov 2026-04-14