Drug Pipeline

Ipatasertib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
15
Active Studies
6
Recruiting
2
Phase 3
6
Top Sponsors
Active Studies by Phase
Phase 3
2
Phase 2
8
Phase 1/2
4
Phase 1
1
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT05862285 A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La… Cancer Recruiting
NCT04650581 Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive… Breast Cancer Active, Not Recruiting
Phase 2
NCT05564377 Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced… Advanced Malignant Solid Neoplasm Recruiting
NCT04920708 Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer… Metastatic Breast Cancer Active, Not Recruiting
NCT04589845 Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You… Solid Tumors Active, Not Recruiting
NCT05498896 Investigate the Contribution of Ipatasertib to Neoadjuvant Chemotherapy Plus Atezolizumab… Triple Negative Breast Cancer Active, Not Recruiting
NCT05172258 Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy… Head and Neck Squamous Cell Carcinoma Active, Not Recruiting
NCT06400251 Testing Ipatasertib as Potentially Targeted Treatment in Cancers With AKT Genetic Changes… Advanced Lymphoma Active, Not Recruiting
NCT02465060 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced… Advanced Lymphoma Active, Not Recruiting
NCT04931342 A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With… Ovarian Cancer Active, Not Recruiting
Phase 1/2
NCT03424005 A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients… Metastatic Breast Cancer Recruiting
NCT04486352 A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer Endometrial Cancer Recruiting
NCT04802759 A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in… Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer Recruiting
NCT05538897 Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal… FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma Active, Not Recruiting
Phase 1
NCT05172245 Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck… Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Recruiting
Sponsors Running Ipatasertib Trials
Disease Areas
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