Disease landscape

Cervical Cancer clinical trials

Get alerts when Cervical Cancer trials change

642 active trials 346 recruiting 48 Phase 3 378 sponsors 104 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 55 of 104 changes on 19 trials

2026-08-14
Trial terminated
Trial terminated: Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial.
Primary endpoint(s) modified
Primary completion moved earlier: 2025-07 → 2025-04-30
Completion moved earlier: 2025-11 → 2025-04-30
NCT05572684 A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants… · NextCure, Inc. · Phase 1/2
2026-08-25
Trial terminated
Primary completion moved earlier: 2029-12-31 → 2026-07-01
Completion moved earlier: 2030-12-31 → 2026-07-31
NCT03356795 Intervention of CAR-T Against Cervical Cancer · Shenzhen Geno-Immune Medical Institute · Phase 1/2
2026-08-25
Trial terminated
Primary completion moved earlier: 2029-12-31 → 2026-07-01
Completion moved earlier: 2030-12-31 → 2026-07-31
NCT03362619 Engineered Immune Effectors Against Cervical Cancer · Shenzhen Geno-Immune Medical Institute · Phase 1/2
2026-08-20
Withdrawn before enrolling
Trial withdrawn: Study withdrawn prior to participant enrollment due to lack of study product.
Primary completion pushed: 2026-07-31 → 2026-12-31
Enrollment reduced: 27 → 0 participants
Sponsor changed: Weill Medical College of Cornell University → University of California, San Diego
Completion pushed: 2026-07-31 → 2026-12-31
NCT07090174 CASCADE: Testing for Safety and Immune Effects of PDS0101, an Anti-HPV Therapy, Among… · University of California, San Diego · Phase 2
2026-08-26
Primary completion pushed: 2026-09-01 → 2028-09-01
Completion pushed: 2028-12-31 → 2030-12-31
NCT05483491 KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer · Christian Hinrichs · Phase 1
2026-08-19
Primary completion pushed: 2025-12-30 → 2027-12-30
NCT05277688 Adjuvant Concurrent Chemoradiotherapy Versus Radiotherapy in Early-stage Cervical Cancer… · Ruijin Hospital · Phase 3
2026-07-31
Primary completion pushed: 2028-08 → 2029-03
Trial sites expanded: 136 → 156 locations
Completion pushed: 2029-08 → 2030-03
NCT04831580 A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer · GOG Foundation
2026-08-14
Primary completion pushed: 2026-07-20 → 2027-07-05
Completion pushed: 2026-07-20 → 2027-07-05
NCT05722288 Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or… · City of Hope Medical Center · Phase 2
2026-08-18
Primary completion pushed: 2027-03-25 → 2030-03-25
Completion moved earlier: 2032-03-25 → 2031-03-25
NCT05463796 InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer · Dana-Farber Cancer Institute
2026-08-22
Primary endpoint(s) modified
Recruitment opened
Enrollment increased: 56 → 299 participants
Trial sites expanded: 0 → 3 locations
Primary completion moved earlier: 2028-08 → 2027-08
Trial arms changed: 2 → 3
NCT07623369 A First-in-Human Study of HH160 in Participants With Advanced or Metastatic Solid Tumors · Huahui Health · Phase 1
2026-08-13
Primary completion pushed: 2026-01 → 2027-01
Completion pushed: 2026-04 → 2027-04
NCT06402383 Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania… · Dr. Karen Yeates
2026-08-12
Primary completion pushed: 2026-07-01 → 2026-10-01
Completion pushed: 2026-07-01 → 2026-10-01
NCT07336134 PopSci CHW4CervixHealth · Thomas Jefferson University
2026-08-11
Primary completion pushed: 2026-12-30 → 2027-12-31
Completion pushed: 2027-03-24 → 2028-03-31
NCT07351110 Improving Cervical Cancer Prevention Among Women Living With Chronic Conditions. · University of Florida
2026-08-06
Primary completion pushed: 2027-10-16 → 2028-10-16
Completion pushed: 2027-10-16 → 2028-10-16
NCT06607874 Self-Collection for Cervical Cancer Screening and HPV Vaccination for Cancer Prevention… · Mayo Clinic
2026-08-01
Primary completion pushed: 2025-06-01 → 2026-08-01
Completion pushed: 2025-07-16 → 2026-08-16
NCT05283421 Improving Diagnostics in Cervical Dysplasia · University of Aarhus
2026-08-19
Primary endpoint(s) modified
Trial completed
Completion moved earlier: 2026-05-29 → 2026-03-31
NCT04432597 HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in… · National Cancer Institute (NCI) · Phase 1/2
2026-08-21
Primary endpoint(s) modified
Trial arms changed: 4 → 5
NCT05269381 Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for… · Mayo Clinic · Phase 1/2
2026-07-31
Primary endpoint(s) modified
Enrollment reduced: 250 → 118 participants
Enrollment closed, study ongoing
NCT07259304 Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors · University of Southern California
2026-08-07
Enrollment reduced: 450 → 165 participants
Enrollment closed, study ongoing
Trial sites reduced: 41 → 36 locations
NCT05581004 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single… · Genentech, Inc. · Phase 1
2026-08-20
Sponsor changed: Queen's University → Dr. Karen Yeates
NCT06402383 Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania… · Dr. Karen Yeates

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-25 NCT07784283 Integrating HPV Education Into School Health Programs in Cambodia and Kenya Clinton Health Access Initiative Inc. new
2026-08-24 NCT07782164 Efficacy of Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors… Amsterdam UMC, location VUmc new
2026-08-24 NCT07781475 Spatially Fractionated Radiation Therapy for Locally Advanced Cervical Cancer The University of Hong Kong-Shenzhen Hospital new
2026-08-20 NCT07777094 TS Triage of HR-HPV Positive Population and Its Accuracy Study Affiliated Hospital of Nantong University new
2026-08-18 NCT07770100 Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy… Mark Bernard new Phase 2
2026-08-17 NCT07768787 Validation of Vaginal Self-Sampling With the Abbott Multi-Collect Swab for HPV Screening… AML new
2026-08-11 NCT07758140 Comparative Self-collection for Cervical Cancer Screening Pivotal Study Mel Mont Medical new
2026-08-04 NCT07743918 Vitamin D Status and Clinical Outcomes in Locally Advanced Cervical Cancer University of Kragujevac new
2026-07-28 NCT07731828 Neoadjuvant Short-course Hypofractionated Radiotherapy Plus Adebrelimab and Platinum… The First Affiliated Hospital with Nanjing Medical University new Phase 2
2026-07-16 NCT07709650 Hypofractionated Chemoradiotherapy for Cervical Cancer Mahidol University new Phase 3

Active trials by phase

Early Phase 1
2
Phase 1
53
Phase 1/2
42
Phase 2
134
Phase 2/3
8
Phase 3
40
Phase 4
11
Not charted: 352 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 642

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07776821 An Exploratory Study on the Efficacy and Safety of Enlonstobart Combined With Concurrent… Tianjin Medical University Cancer Institute and Hospital Recruiting 2026-08-25
NCT06952660 Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical… Pfizer Recruiting 2026-08-17
NCT07645625 Pembrolizumab Registry for Outcomes and Treatment Evaluation in Cervical Cancer University Medical Center Groningen Recruiting 2026-06-29
NCT04910802 Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden Miriam Elfström Recruiting 2021-09-16
NCT07768358 Tucatinib Continuation Study Pfizer Not Yet Recruiting 2026-08-17
NCT07015957 Kupewa: Optimizing Implementation Strategies for Cervical Cancer Prevention New York University Active, Not Recruiting 2026-08-05
NCT05237947 Single-Dose HPV Vaccination for the Prevention of Cervical Cancer in Young Adult Women in… National Cancer Institute (NCI) Active, Not Recruiting 2026-06-30
NCT07256912 A Trial to Establish Non-inferiority of Immunogenicity of a Single-dose of CERVAVAC®… International Agency for Research on Cancer Not Yet Recruiting 2026-03-24
NCT07412873 Study on Sexual Health and Self-perceived Quality of Life (PROMs) in Patients Treated for… Fundacion Clinic per a la Recerca Biomédica Not Yet Recruiting 2026-02-17
NCT03180034 Comparing One or Two Doses of the Human Papillomavirus Vaccine for the Prevention of… National Cancer Institute (NCI) Active, Not Recruiting 2025-09-04
NCT06871787 Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses… Istanbul University Not Yet Recruiting 2025-03-14
Phase 3
NCT07061977 Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation… National Cancer Institute (NCI) Recruiting 2026-08-27
NCT06079671 Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer… AstraZeneca Recruiting 2026-08-25
NCT07216703 A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab… Merck Sharp & Dohme LLC Recruiting 2026-08-24
NCT05277688 Adjuvant Concurrent Chemoradiotherapy Versus Radiotherapy in Early-stage Cervical Cancer… Ruijin Hospital Recruiting 2026-08-18
NCT05581121 PARa-aOrtic LymphAdenectomy in Locally Advanced Cervical Cancer Institut Claudius Regaud Recruiting 2026-07-07
NCT07400536 A Clinical Study on the Treatment of LACC With Cadonilimab Combined With Chemotherapy… Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Recruiting 2026-05-13
NCT07168200 A Phase III Clinical Study of Adebrelimab Combined With Concurrent Chemoradiotherapy… Shanghai Shengdi Pharmaceutical Co., Ltd Recruiting 2026-04-15
NCT07418749 A Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With… Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting 2026-04-06
NCT06156514 Evaluation of Concomitant Chemo-radiotherapy With Cisplatine vs Gemcitabin in Locally… National Institute of Cancerología Recruiting 2025-05-28
NCT06459687 Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or… Lee's Pharmaceutical Limited Recruiting 2025-05-14
NCT06641635 Moderated Hypofractionated Online Adaptive Radiotherapy in Cervical Cancer Peking Union Medical College Hospital Recruiting 2025-03-18
NCT06692166 A Study to Evaluate 9MW2821 Versus Treatment of Physician's Choice for Subjects With… Mabwell (Shanghai) Bioscience Co., Ltd. Recruiting 2024-11-22
NCT05764044 Adjuvant Chemotherapy in cfHPV-DNA Plasma Positive Patients: A Biomarker In Locally… Hospital do Coracao Recruiting 2024-07-30
NCT06509724 Comparison of Conventional and Hypofractionated IMRT in High-Risk Cervical Cancer… Samsung Medical Center Recruiting 2024-07-26
See all 642 active Cervical Cancer trials with filters →

Top sponsors by active trials in this area

M.D. Anderson Cancer Center (17) · National Cancer Institute (NCI) (15) · Peking Union Medical College Hospital (11) · Chongqing University Cancer Hospital (10) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (10) · Mayo Clinic (10) · Obstetrics & Gynecology Hospital of Fudan University (9) · Fujian Cancer Hospital (7) · Tongji Hospital (7) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (6)

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