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NCT07782164 · ClinicalTrials.gov record · last posted 2026-08-24

Efficacy of Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors (PELFIRE Study)

Name: Efficacy of Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors (PELFIRE Study) — clinical trial record (NCT07782164)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: PELFIRE

StatusRecruiting

PhaseNot specified

SponsorAmsterdam UMC, location VUmc

Started2025-04-18

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from the ClinicalTrials.gov record

The goal of this single-center observational cohort study, based on a registry combining retrospectively and prospectively collected data, is to investigate the short- and long-term effects of irreversible electroporation (IRE) in men and women over the age of 18 who receive IRE for recurrence of pelvic tumors not suitable for other local treatment options such as surgery, thermal ablation, and radiotherapy. The main question it aims to answer is whether IRE is safe in this population, and secondarily, whether it is effective in controlling local tumor recurrence.

Trial Details

NCT Number	NCT07782164
Lead Sponsor	Amsterdam UMC, location VUmc
Conditions	Colorectal Carcinoma, Pelvic Cancer, Pelvic Tumor Recurrence, Renal Cancer, Bladder Cancer, Cervical Cancer, Prostate Cancer, Ovarian Cancer +2 more
Enrollment	27 participants
Start Date	2025-04-18
Primary Completion	2028-06 (estimated)
Study Completion	2028-07 (estimated)
Updated on ClinicalTrials.gov	2026-08-24