| Detected | Trial | Change |
|---|---|---|
| 2026-08-14 | NCT07552558 Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and… · Washington University School of Medicine |
date change Primary completion pushed: 2028-08-31 -> 2028-11-30 |
| 2026-08-14 | NCT07552558 Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and… · Washington University School of Medicine |
date change Completion pushed: 2033-08-31 -> 2033-11-30 |
| 2026-08-13 | NCT05635643 Study of CHS-114 in Participants With Advanced Solid Tumors · Coherus Oncology, Inc. |
Enrollment closed, study ongoing |
| 2026-08-13 | NCT05635643 Study of CHS-114 in Participants With Advanced Solid Tumors · Coherus Oncology, Inc. |
Trial sites reduced: 16 -> 12 locations |
| 2026-08-13 | NCT06531083 Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus · University of Alberta |
date change Primary completion pushed: 2026-06-30 -> 2026-09-30 |
| 2026-08-13 | NCT06531083 Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus · University of Alberta |
date change Completion pushed: 2026-08-31 -> 2026-09-30 |
| 2026-08-13 | NCT06289049 Heavy Strength Training in Head and Neck Cancer Survivors · University of Alberta |
Trial completed |
| 2026-08-13 | NCT06289049 Heavy Strength Training in Head and Neck Cancer Survivors · University of Alberta |
Enrollment reduced: 60 -> 37 participants |
| 2026-08-13 | NCT06289049 Heavy Strength Training in Head and Neck Cancer Survivors · University of Alberta |
date change Primary completion pushed: 2026-06 -> 2026-07-06 |
| 2026-08-13 | NCT06289049 Heavy Strength Training in Head and Neck Cancer Survivors · University of Alberta |
date change Completion pushed: 2026-06 -> 2026-07-06 |
| 2026-08-12 | NCT03708224 Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck · Alain Algazi |
Enrollment closed, study ongoing |
| 2026-08-12 | NCT03708224 Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck · Alain Algazi |
date change Primary completion moved earlier: 2028-06-30 -> 2027-07-31 |
| 2026-08-12 | NCT03708224 Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck · Alain Algazi |
date change Completion moved earlier: 2028-06-30 -> 2027-07-31 |
| 2026-08-11 | NCT06145412 A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With… · Memorial Sloan Kettering Cancer Center |
Trial completed |
| 2026-08-11 | NCT06145412 A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With… · Memorial Sloan Kettering Cancer Center |
date change Primary completion moved earlier: 2026-11 -> 2026-08-04 |
| 2026-08-11 | NCT06145412 A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With… · Memorial Sloan Kettering Cancer Center |
date change Completion moved earlier: 2026-11 -> 2026-08-04 |
| 2026-08-11 | NCT07744126 A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of… · AbbVie |
Trial sites reduced: 20 -> 0 locations |
| 2026-08-11 | NCT02955290 CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced… · Roswell Park Cancer Institute |
date change Primary completion pushed: 2025-05-23 -> 2026-11-25 |
| 2026-08-11 | NCT06666881 Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise… · Chang Gung Memorial Hospital |
Primary endpoint(s) modified |
| 2026-08-11 | NCT06666881 Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise… · Chang Gung Memorial Hospital |
date change Primary completion pushed: 2025-09-30 -> 2027-09-30 |
| First Posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-08-12 | NCT07759193 Energy Expenditure Assessment in Head and Neck Cancer Patients Treated With Free Flap… | Tel-Aviv Sourasky Medical Center NEW | |
| 2026-08-11 | NCT07756684 Feasibility of Cough Skill Training in Individuals With Head and Neck Cancer | Boston University Charles River Campus NEW | |
| 2026-08-10 | NCT07755449 CLEAR (Cervical Lymphatic Exclusion in Adjuvant Radiation) | Institut Català d'Oncologia NEW | Phase 2 |
| 2026-08-05 | NCT07748442 Benzydamine vs Supersaturated Calcium Phosphate Oral Rinses for Radiation Induced Oral… | Postgraduate Medical Institute, Lahore NEW | |
| 2026-08-04 | NCT07743723 A Study of IOV-5001 in Adults With Advanced Solid Tumors | Iovance Biotherapeutics NEW | Phase 1/2 |
| 2026-07-17 | NCT07711626 Foot Reflexology and Ta-VNS for Symptom Management in Head and Neck Cancer During CCRT | Tzu Chi University NEW | |
| 2026-07-17 | NCT07712120 Brief Clinical Psychological Intervention With Biofeedback in Head and Neck Cancer | University of Turin, Italy NEW | |
| 2026-07-16 | NCT07707167 A Prospective, Exploratory Study of Becotatug Vedotin Plus Putlimab for Neoadjuvant… | Jiangsu Cancer Institute & Hospital NEW | Phase 2 |
| 2026-07-15 | NCT07705074 FAPI PET Imaging - An Exploratory Study | Martin Huellner NEW | Phase 1/2 |
| 2026-07-13 | NCT07697287 Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An… | McMaster University NEW | Phase 4 |
| NCT ID | Title | Sponsor | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT06734598 | Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with… | National Taiwan University Hospital | Recruiting |
| NCT07189897 | Apixaban or Enoxaparin After Head and Neck Cancer Surgery | Kiranya Arnold | Recruiting |
| NCT06162377 | Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of… | M.D. Anderson Cancer Center | Recruiting |
| NCT07405086 | Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or… | OHSU Knight Cancer Institute | Recruiting |
| NCT06807034 | Impact of the Oral Microbiota on Relapse in HNSCC Patients | Institut Sainte Catherine | Active, Not Recruiting |
| NCT06879691 | A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous… | Biotech Pharmaceutical Co., Ltd. | Active, Not Recruiting |
| NCT07633613 | Pharmacokinetic Study of Pembrolizumab and Its Impact on Immunity and the Tumor… | Centre Antoine Lacassagne | Not Yet Recruiting |
| NCT07635420 | Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical… | Region Skane | Not Yet Recruiting |
| Phase 3 | |||
| NCT05044117 | Single-agent Capecitabine as Metronomic Chemotherapy in LAHNSCC (CMHN) | Sun Yat-sen University | Recruiting |
| NCT05980715 | PD-1 Inhibitor Therapy Versus Radiotherapy in pCR Patients With Locally Advanced HNSCC… | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Recruiting |
| NCT06102395 | Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the… | Beijing Tongren Hospital | Recruiting |
| NCT05582265 | Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in… | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Recruiting |
| NCT06248996 | a Multicentre Phase III Study of Risk-based Treatment Intensification With… | Lund University Hospital | Recruiting |
| NCT06601335 | A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head… | Akeso | Recruiting |
| NCT04178174 | Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer | Centre hospitalier de l'Université de Montréal (CHUM) | Recruiting |
| NCT06699212 | A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line… | Rakuten Medical, Inc. | Recruiting |
| NCT07467083 | Development and Application of a Nurse-Led Preemptive Symptom Management Protocol for… | West China Hospital | Recruiting |
| NCT06064877 | A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or… | AVEO Pharmaceuticals, Inc. | Recruiting |
| NCT07524452 | Becotatug Vedotin (MRG003) in Combination With PD-1 Inhibitor Versus PD-1 Inhibitor for… | Ming-Yuan Chen | Recruiting |
| NCT06992427 | High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral… | Alliance for Clinical Trials in Oncology | Recruiting |
| NCT07580300 | Proton Versus Photon Therapy in Head and Neck Squamous Cell Carcinomas. | Oslo University Hospital | Recruiting |
| NCT04966481 | Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered… | Washington University School of Medicine | Recruiting |
| NCT07264075 | Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus… | Groupe Oncologie Radiotherapie Tete et Cou | Recruiting |
| NCT06525220 | A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in… | Merus B.V. | Recruiting |
| NCT06641791 | Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in… | Canadian Cancer Trials Group | Recruiting |