Disease landscape

Prostate Cancer clinical trials

Get alerts when Prostate Cancer trials change

1,907 active trials 1,075 recruiting 174 Phase 3 742 sponsors 242 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 46 of 242 changes on 20 trials

2026-08-28
Withdrawn before enrolling
Trial withdrawn: Other - Protocol moved to Withdrawn
Enrollment reduced: 24 → 0 participants
NCT06982222 Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have… · National Cancer Institute (NCI) · Phase 1
2026-08-25
Trial terminated
Primary completion moved earlier: 2028-06-15 → 2026-07-15
Completion moved earlier: 2028-12-15 → 2026-07-31
NCT07068555 Prostate Cancer Vaccines · Shenzhen Geno-Immune Medical Institute · Phase 1/2
2026-08-21
Recruitment suspended
Recruitment suspended: Pending additional funding.
NCT06200103 Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate… · Mayo Clinic · Phase 2
2026-08-14
Trial status changed: Completed → Terminated
Trial terminated: Accrual and drug manufacturing and supply were discontinued in 2025.
NCT02769962 Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With… · National Cancer Institute (NCI) · Phase 1/2
2026-07-30
Recruitment suspended
Recruitment suspended: On hold pending consideration of an amendment to increase recruitment.
NCT04808427 Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate… · National Cancer Institute (NCI)
2026-08-04
Recruitment suspended
Recruitment suspended: Protocol being updates and staff trained
NCT04646434 Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing… · Roswell Park Cancer Institute
2026-08-27
Primary completion pushed: 2029-02-13 → 2029-06-04
Trial sites expanded: 104 → 132 locations
Completion pushed: 2029-12-20 → 2030-06-06
NCT07611110 AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant… · AstraZeneca · Phase 3
2026-08-22
Primary completion pushed: 2025-12-15 → 2028-12-15
NCT06872619 RegisterPROS - A Registry for Prostate Cancers · Wren Laboratories LLC
2026-08-15
Primary completion pushed: 2025-05-20 → 2026-01-21
Trial status changed: Unknown → Completed
Trial sites expanded: 1 → 8 locations
Completion pushed: 2025-05-20 → 2026-03-09
NCT06490328 Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancer · Dongkook Pharmaceutical Co., Ltd. · Phase 3
2026-08-12
Primary completion pushed: 2026-07-13 → 2026-12-28
Trial sites reduced: 230 → 224 locations
NCT06551324 A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in… · Pfizer · Phase 3
2026-08-26
Primary completion pushed: 2026-08-01 → 2027-08-01
Completion pushed: 2027-02 → 2028-02
NCT06024772 Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer · Thomas Jefferson University · Phase 3
2026-08-15
Primary completion pushed: 2026-07-31 → 2026-10-31
Completion pushed: 2026-07-31 → 2026-10-31
NCT03436485 Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant… · Orion Corporation, Orion Pharma · Phase 1/2
2026-08-11
Primary completion pushed: 2028-06-15 → 2028-10-15
NCT07450599 A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy… · Bayer · Phase 2
2026-08-05
Primary completion pushed: 2028-03-01 → 2028-12-31
Enrollment increased: 67 → 88 participants
Completion pushed: 2028-08-01 → 2028-12-31
NCT06801236 Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate… · Acerand Therapeutics (Hong Kong) Limited · Phase 1
2026-08-28
Primary completion pushed: 2026-10-02 → 2028-02-13
Enrollment reopened
Enrollment increased: 33 → 51 participants
Completion pushed: 2026-12-20 → 2028-02-13
NCT04589468 Researching the Effect of Exercise on Cancer · City of Hope Medical Center
2026-08-27
Primary completion pushed: 2026-08 → 2029-08
Completion pushed: 2026-08 → 2029-08
NCT02871726 Transrectal Ultrasound Robot-Assisted Prostate Biopsy · Johns Hopkins University
2026-08-27
Primary completion pushed: 2028-05-30 → 2028-10-30
Completion pushed: 2029-06-30 → 2029-10-30
NCT06960798 Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations… · University of Oklahoma
2026-08-18
Primary completion pushed: 2026-07 → 2027-07
Completion pushed: 2026-07 → 2027-07
NCT01407263 Trial of Modifications to Radical Prostatectomy · Memorial Sloan Kettering Cancer Center · Phase 3
2026-08-22
Primary completion pushed: 2026-02-28 → 2028-02-28
Completion pushed: 2026-02-28 → 2028-02-28
NCT04189770 Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate… · M.D. Anderson Cancer Center
2026-08-22
Primary completion pushed: 2028-07 → 2029-07
Completion moved earlier: 2033-07 → 2033-01
NCT07591051 Weekly Online CT or MR Adaptive Definitive SBRT for Regionally Metastatic Prostate Cancer · University of Zurich

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-24 NCT07781852 Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and… Lumina Pharmaceuticals Inc new Early Phase 1
2026-08-24 NCT07782112 Best Salvage Treatment for High-risk Relapsing Prostate Cancer (PEACE-9 - ESCALATE-RT) Ente Ospedaliero Cantonale, Bellinzona new Phase 3
2026-08-24 NCT07782164 Efficacy of Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors… Amsterdam UMC, location VUmc new
2026-08-20 NCT07777263 ADT De-escalation in Selected High-Risk Prostate Cancer Patients (ADaPPt Trial) a GROUQ… Dr. Tamim Niazi new Phase 3
2026-08-14 NCT07766122 Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer… University Hospital, Toulouse new Phase 4
2026-08-14 NCT07766603 Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical… ALİ DEMİRTAŞ new
2026-08-14 NCT07765940 Safety and Preliminary Diagnostic Performance of [⁶⁴Cu]Cu-RAX301 in Prostate Cancer RadAlliance Therapeutics, Inc new Phase 1/2
2026-08-11 NCT07757490 Sonablate HIFU International Registry for PC & BPH Patients Sonablate new
2026-08-10 NCT07754929 E-Mergir: A Digital Psychosexual Intervention for the Promotion of Mental and Sexual… Universidade do Porto new
2026-08-07 NCT07753356 VALIDATION OF FUSION CEMEP SCORE FOR OMITTING SYSTEMATIC PROSTATE BIOPSY Marcelo Ruben Oliva new

Active trials by phase

Early Phase 1
43
Phase 1
174
Phase 1/2
134
Phase 2
380
Phase 2/3
25
Phase 3
149
Phase 4
27
Not charted: 975 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,907

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07252726 Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic… Ottawa Hospital Research Institute Recruiting 2026-07-17
NCT05348876 A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real… Bayer Recruiting 2026-07-06
NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate… Novartis Pharmaceuticals Recruiting 2026-06-04
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men… Roswell Park Cancer Institute Recruiting 2026-05-14
NCT06099093 Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan Brigham and Women's Hospital Recruiting 2026-01-29
NCT05919329 Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal… OHSU Knight Cancer Institute Recruiting 2025-10-24
NCT06908694 Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen… Hamilton Health Sciences Corporation Recruiting 2025-07-29
NCT07001709 Determining the Effect of Abiraterone on the Metabolism of Oxycodone in Men With Prostate… Deventer Ziekenhuis Recruiting 2025-06-03
NCT05805436 Preop Laxatives in Robotic Urologic Surgery Chad R. Tracy Recruiting 2025-05-30
NCT06784986 Impact of Using the Airseal System With Ultra-low Pneumoperitoneum in Patients Undergoing… Brazilian Institute of Robotic Surgery Recruiting 2025-01-20
NCT06706921 18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy… VA Greater Los Angeles Healthcare System Recruiting 2024-11-27
NCT05629494 Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test Albany Medical College Recruiting 2024-10-18
NCT06001619 Prostate Medication, Metabolism and Gut Microbiota Turku University Hospital Recruiting 2023-08-21
NCT07766122 Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer… University Hospital, Toulouse Not Yet Recruiting 2026-08-14
NCT07278362 Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under… University of Miami Not Yet Recruiting 2026-07-22
NCT04549207 Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients… Ottawa Hospital Research Institute Active, Not Recruiting 2026-07-21
NCT04597125 RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs… Bayer Active, Not Recruiting 2026-07-06
NCT07677566 177Lu-PSMA-617 Combined With Darolutamide in Neoadjuvant Treatment of High-risk Localized… The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Not Yet Recruiting 2026-07-01
NCT05722925 Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer… OHSU Knight Cancer Institute Active, Not Recruiting 2026-06-29
NCT07569926 Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of… Blue Earth Diagnostics Not Yet Recruiting 2026-06-02
NCT05753046 Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for… Corewell Health East Enrolling by Invitation 2026-04-23
NCT05457257 Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With… AstraZeneca Active, Not Recruiting 2026-04-21
NCT03016741 Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer Northwestern University Active, Not Recruiting 2026-02-24
NCT06627530 COACTION Trial - COmbination Androgen bloCkade in inTermediate to hIgh-risk prOstate… Brazilian Clinical Research Institute Active, Not Recruiting 2026-02-11
NCT06660862 Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in… University of Chicago Not Yet Recruiting 2026-01-08
See all 1,907 active Prostate Cancer trials with filters →

Top sponsors by active trials in this area

M.D. Anderson Cancer Center (41) · Memorial Sloan Kettering Cancer Center (40) · National Cancer Institute (NCI) (37) · Jonsson Comprehensive Cancer Center (30) · AstraZeneca (26) · Mayo Clinic (26) · University Health Network, Toronto (26) · Novartis Pharmaceuticals (25) · City of Hope Medical Center (21) · Chinese University of Hong Kong (20)

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