Disease landscape

Gastric Cancer clinical trials

Get alerts when Gastric Cancer trials change

818 active trials 462 recruiting 76 Phase 3 416 sponsors 105 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 54 of 105 changes on 20 trials

2026-08-14
Trial terminated
Trial terminated: Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial.
Primary endpoint(s) modified
Primary completion moved earlier: 2025-07 → 2025-04-30
Completion moved earlier: 2025-11 → 2025-04-30
NCT05572684 A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants… · NextCure, Inc. · Phase 1/2
2026-07-30
Trial terminated
Trial terminated: Sponsor Decision
Completion moved earlier: 2026-08-12 → 2025-11-21
NCT05322577 A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in… · Amgen · Phase 1/2
2026-08-22
Recruitment suspended
Recruitment suspended: Gilead's ongoing evaluation of the wider Zimberelimab and Domvanalimab programme, following the outcomes of the ST...
NCT06250036 Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer · Royal Marsden NHS Foundation Trust · Phase 2
2026-08-12
Primary completion pushed: 2025-06-30 → 2026-12-30
Sponsor changed: Evopoint Biosciences Inc. → Astellas Pharma Global Development, Inc.
Enrollment closed, study ongoing
Completion pushed: 2025-12-31 → 2027-06-30
NCT06792435 XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies. · Astellas Pharma Global Development, Inc. · Phase 1/2
2026-07-30
Primary completion pushed: 2026-08-11 → 2026-11-17
Completion moved earlier: 2027-09-30 → 2027-06-28
NCT06219941 AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 · AstraZeneca · Phase 2
2026-07-30
Primary completion pushed: 2026-10-30 → 2033-07
Primary endpoint(s) modified
Enrollment reopened
Enrollment increased: 296 → 340 participants
Completion pushed: 2027-05-12 → 2033-07
Trial arms changed: 14 → 15
NCT04198766 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in… · Inhibrx Biosciences, Inc · Phase 1/2
2026-07-30
Primary completion pushed: 2025-11 → 2028-05
Primary endpoint(s) modified
Trial sites expanded: 45 → 54 locations
Completion pushed: 2027-11 → 2028-11
NCT03526835 A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors · Merus B.V. · Phase 1/2
2026-08-06
Primary completion pushed: 2026-05 → 2027-06
Primary endpoint(s) modified
Completion pushed: 2026-05 → 2027-06
Trial arms changed: 17 → 18
NCT04999761 AB122 Platform Study · Taiho Pharmaceutical Co., Ltd. · Phase 1
2026-08-26
Primary completion pushed: 2026-09-01 → 2028-09-01
Completion pushed: 2028-12-31 → 2030-12-31
NCT05483491 KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer · Christian Hinrichs · Phase 1
2026-08-19
Primary completion pushed: 2026-08-01 → 2028-08-01
Primary endpoint(s) modified
Phase changed: Phase 2/3 → Phase 2
Completion pushed: 2028-08-01 → 2029-08-01
NCT06826079 Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With… · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Phase 2
2026-08-19
Primary completion pushed: 2026-06 → 2027-07
NCT07025889 IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer · Ruijin Hospital · Phase 1/2
2026-08-20
Primary completion pushed: 2026-06-15 → 2026-10-01
Completion pushed: 2026-06-15 → 2026-10-01
NCT05203627 Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach… · City of Hope Medical Center
2026-08-26
Primary endpoint(s) modified
NCT07781852 Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and… · Lumina Pharmaceuticals Inc · Early Phase 1
2026-08-07
Primary completion pushed: 2030-12-31 → 2031-04-30
Completion pushed: 2030-12-31 → 2031-04-30
NCT07101666 Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Washington University School of Medicine · Phase 2
2026-07-30
Primary completion pushed: 2026-05 → 2027-01
Completion pushed: 2026-12 → 2027-01
NCT06519591 Systemic Application of Cadonilimab, LM-302, and S-1 Combined With Intraperitoneal… · Ruijin Hospital · Phase 2
2026-08-15
Primary completion pushed: 2026-06-30 → 2027-04-30
NCT04221893 Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers · University of California, San Francisco
2026-08-05
Primary completion pushed: 2025-11-20 → 2027-12-31
Recruitment opened
Completion pushed: 2027-11-20 → 2027-12-31
NCT07237126 Single-port Robotic Radical Gastrectomy for Gastric Cancer · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
2026-08-21
Primary endpoint(s) modified
Trial arms changed: 4 → 5
NCT05269381 Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for… · Mayo Clinic · Phase 1/2
2026-08-22
Primary endpoint(s) modified
NCT06788548 Fluorescence Guided Laparoscopic-Endoscopic Cooperative Sentinel Lymph Node Navigation… · Beijing Friendship Hospital
2026-08-04
Primary endpoint(s) modified
Phase changed: not specified → Phase 2
Trial arms changed: 0 → 1
NCT07490990 Disitamab Vedotin Combined With Sintilimab and Multimodal Radiotherapy for HER2-Positive… · West China Hospital · Phase 2

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-27 NCT07789184 Radical Surgery Versus Non-Surgery in Gastric Cancer Patients With Peritoneal Metastasis… Hua Huang, MD, PhD new Phase 3
2026-08-24 NCT07781852 Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and… Lumina Pharmaceuticals Inc new Early Phase 1
2026-08-24 NCT07782294 AI-Assisted Novel rbcDNA Detection for Early Gastric Cancer Diagnosis Second Affiliated Hospital, Zhejiang University, School of Medicine new
2026-08-24 NCT07781319 Early Gastric Cancer in the Spanish EURECCA Registry Corporacion Parc Tauli new
2026-08-19 NCT07772453 Ferric Carboxymaltose Versus Iron Sucrose for Iron Deficiency Anemia After Radical… Zhaojian Niu,MD new Phase 4
2026-08-18 NCT07770100 Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy… Mark Bernard new Phase 2
2026-08-18 NCT07770126 The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter… Universiteit Antwerpen new
2026-07-29 NCT07732543 Developing and Testing the Effectiveness of Smart Healthcare Assisted Individualized… Taipei Veterans General Hospital, Taiwan new
2026-07-20 NCT07715747 A Phase I Study to Evaluate the Safety,Pharmacokinetics,Pharmacodynamics,and Efficacy of… TJ Biopharma Co., Ltd. new Phase 1
2026-07-16 NCT07708012 Clinical Study on Using Laparoscopic Sentinel Lymph Node Navigation Combined With Dual… wangdongsheng new

Active trials by phase

Early Phase 1
14
Phase 1
93
Phase 1/2
68
Phase 2
192
Phase 2/3
18
Phase 3
58
Phase 4
14
Not charted: 361 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 818

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT05183126 Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With… University of Michigan Rogel Cancer Center Recruiting 2026-07-02
NCT07139366 Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori… Yongquan Shi Recruiting 2025-12-02
NCT07124351 Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™) Cedars-Sinai Medical Center Recruiting 2025-09-15
NCT07068607 Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for… Yongquan Shi Recruiting 2025-08-14
NCT02047994 Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for… International Agency for Research on Cancer Recruiting 2025-05-02
NCT07772453 Ferric Carboxymaltose Versus Iron Sucrose for Iron Deficiency Anemia After Radical… Zhaojian Niu,MD Not Yet Recruiting 2026-08-19
NCT07502027 A Clinical Study of Iparomlimab and Tuvonralimab Combined With SOX Following… Huazhong University of Science and Technology Not Yet Recruiting 2026-03-30
NCT07312370 Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing LanZhou University Not Yet Recruiting 2026-03-23
NCT07467174 RCT Comparing Reduced-port Robotic and Conventional Laparoscopic Subtotal Gastrectomy Yonsei University Not Yet Recruiting 2026-03-12
NCT07224035 Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community- AIM 1 University of Miami Active, Not Recruiting 2026-02-17
NCT07224048 Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community-AIM 2 University of Miami Active, Not Recruiting 2026-02-17
NCT06499610 Clinical Study of Irinotecan Liposome Combination Therapy for Advanced Gastric Cancer First Affiliated Hospital Xi'an Jiaotong University Not Yet Recruiting 2024-07-12
NCT05498766 Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Not Yet Recruiting 2024-06-24
NCT04168346 Preoperative Intravenous Iron Therapy in Patients With Gastric Cancer Helsinki University Central Hospital Not Yet Recruiting 2019-11-19
Phase 3
NCT06731478 Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic… Daiichi Sankyo Recruiting 2026-08-10
NCT05677490 mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced… Alliance for Clinical Trials in Oncology Recruiting 2026-08-05
NCT07518147 A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in… Sichuan Baili Pharmaceutical Co., Ltd. Recruiting 2026-07-08
NCT07304271 Intraperitoneal Paclitaxel and Systemic Therapy Versus Systemic Therapy Alone in Gastric… Magnus Nilsson Recruiting 2026-07-07
NCT07431281 Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in… AstraZeneca Recruiting 2026-07-01
NCT07217704 Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or… SOFIE Recruiting 2026-06-30
NCT06346197 Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric… Centre Leon Berard Recruiting 2026-06-25
NCT06764875 A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab… AstraZeneca Recruiting 2026-06-16
NCT05593458 Transarterial Neoadjuvant Chemotherapy vs.Traditional Intravenous Chemotherapy For… Zhejiang University Recruiting 2026-06-11
NCT05226169 Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric… Asan Medical Center Recruiting 2026-04-03
NCT05871099 Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic… The Affiliated Hospital of Qingdao University Recruiting 2026-03-06
See all 818 active Gastric Cancer trials with filters →

Top sponsors by active trials in this area

Fudan University (20) · The First Affiliated Hospital with Nanjing Medical University (20) · National Cancer Institute (NCI) (17) · AstraZeneca (16) · Fujian Medical University (14) · Qilu Hospital of Shandong University (12) · Nanfang Hospital, Southern Medical University (11) · City of Hope Medical Center (9) · Memorial Sloan Kettering Cancer Center (9) · Ruijin Hospital (9)

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