Sponsor Pipeline

Amgen Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
87
Active Trials
42
Recruiting
40
Phase 3
10
Disease Areas
50
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT07575399
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor…
Recruitment opened
2026-06-12 NCT07575399
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor…
Trial sites expanded: 0 -> 40 locations
2026-06-11 NCT07388498
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and…
Trial sites expanded: 37 -> 49 locations
2026-06-11 NCT07388498
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and…
date change Completion moved earlier: 2028-07-18 -> 2028-06-18
2026-06-11 NCT06252649
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without…
Trial sites expanded: 286 -> 290 locations
2026-06-11 NCT06252649
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without…
date change Primary completion pushed: 2028-01-31 -> 2028-09-25
2026-06-11 NCT06252649
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without…
date change Completion pushed: 2031-08-31 -> 2032-04-25
2026-06-10 NCT06700343
Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-10 NCT06700343
Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)
Enrollment reduced: 444 -> 152 participants
2026-06-05 NCT07403721
AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid…
Trial sites expanded: 10 -> 14 locations
2026-06-05 NCT07213674
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With…
Trial sites expanded: 129 -> 133 locations
2026-06-05 NCT07226765
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea…
Trial sites expanded: 49 -> 53 locations
2026-06-02 NCT06360354
A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With…
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-02 NCT06360354
A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With…
Enrollment reduced: 350 -> 120 participants
2026-06-02 NCT06360354
A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With…
date change Primary completion moved earlier: 2027-02-26 -> 2026-10-31
2026-06-02 NCT06360354
A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With…
date change Completion moved earlier: 2029-02-25 -> 2026-11-30
2026-05-30 NCT07037433
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in…
Trial sites expanded: 769 -> 772 locations
2026-05-29 NCT06593522
A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC…
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-29 NCT06593522
A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC…
Enrollment reduced: 200 -> 61 participants
2026-05-29 NCT06593522
A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC…
date change Primary completion moved earlier: 2028-11-29 -> 2026-10-31
Showing 20 of 50 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-05-29 NCT07614776 A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA®… Phase 3 Not Yet Recruiting
2026-05-20 NCT07598825 A Trial of Inebilizumab in Participants With Autoimmune Hepatitis Phase 3 Not Yet Recruiting
2026-05-15 NCT07590193 A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes… Phase 1 Not Yet Recruiting
Active Trials by Phase
Phase 4
3
Phase 3
40
Phase 2
11
Phase 1/2
5
Phase 1
26
Not specified
2
Active Trials — top 25 of 87
NCT IDTitleConditionStatus
Phase 4
NCT06072482 A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis Antineutrophil Cytoplasmic Antibody-associated Vasculitis Recruiting
NCT06332014 Evaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland… Osteoporosis Active, Not Recruiting
NCT06588153 A Study for the Evaluation of Efficacy and Safety of Prolia® in Participants With… Glucocorticoid-induced Osteoporosis Active, Not Recruiting
Phase 3
NCT03633708 A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and… Secondary Hyperparathyroidism Recruiting
NCT03969329 A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving… Secondary Hyperparathyroidism Recruiting
NCT07293260 Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary… Cardiovascular Disease Recruiting
NCT04804553 Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis Active Juvenile Psoriatic Arthritis Recruiting
NCT06747949 A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) Sjögren's Syndrome Recruiting
NCT07366086 Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis… Osteogenesis Imperfecta Recruiting
NCT06321601 Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing… Vasculitis Recruiting
NCT07037459 Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection… Heart Failure With Preserved Ejection Fraction Recruiting
NCT07225686 Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea… Obesity Recruiting
NCT07037433 Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in… Atherosclerotic Cardiovascular Disease Recruiting
NCT05920356 A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum… Non-Small Cell Lung Cancer (NSCLC) Recruiting
NCT07005128 A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab… Small-cell Lung Cancer Recruiting
NCT07136012 OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a)… Cardiovascular Disease Recruiting
NCT07213674 A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With… Metastatic Castration-resistant Prostate Cancer Recruiting
NCT07226765 Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea… Obstructive Sleep Apnea Recruiting
NCT06252649 Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without… Metastatic Colorectal Cancer Recruiting
NCT07388498 A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and… Uncontrolled Gout Recruiting
NCT07575399 Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor… Obesity or Overweight Recruiting
NCT06858878 Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes… Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight Active, Not Recruiting
NCT05740566 Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung… Small Cell Lung Cancer (SCLC) Active, Not Recruiting
NCT06245408 A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)… Sjögren's Syndrome (SS) Active, Not Recruiting
NCT06054555 A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With… Melanoma Active, Not Recruiting
View all 87 active Amgen trials with filters →
Disease Areas
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