Sponsor Pipeline

Roswell Park Cancer Institute Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
85
Active Trials
53
Recruiting
1
Phase 3
10
Disease Areas
19
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-11 NCT02955290
CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced…
date change Primary completion pushed: 2025-05-23 -> 2026-11-25
2026-08-08 NCT02455557
SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed…
date change Completion pushed: 2026-06-02 -> 2026-09-02
2026-08-08 NCT06305598
Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for…
Enrollment closed, study ongoing
2026-08-08 NCT06305598
Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for…
Enrollment reduced: 14 -> 3 participants
2026-08-08 NCT06305598
Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for…
date change Primary completion moved earlier: 2029-12-15 -> 2026-03-09
2026-08-08 NCT06305598
Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for…
date change Completion moved earlier: 2029-12-15 -> 2028-03-09
2026-08-07 NCT04876248
Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients…
date change Primary completion pushed: 2026-09-01 -> 2026-12-01
2026-08-04 NCT04646434
Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing…
critical Recruitment suspended
2026-08-04 NCT04646434
Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing…
critical Recruitment suspended: Protocol being updates and staff trained
2026-08-01 NCT07679334
Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the…
date change Primary completion pushed: 2028-08-01 -> 2028-09-01
2026-08-01 NCT07679334
Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the…
date change Completion pushed: 2029-08-01 -> 2029-09-01
2026-07-30 NCT06681077
A Community Health Education Intervention for Increasing Community-driven Actions to…
Primary endpoint(s) modified
2026-07-30 NCT06681077
A Community Health Education Intervention for Increasing Community-driven Actions to…
Trial arms changed: 1 -> 2
2026-07-29 NCT06029517
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
Trial completed
2026-07-29 NCT06029517
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
date change Completion moved earlier: 2026-09-15 -> 2025-09-15
2026-07-24 NCT06320717
AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic…
date change Primary completion pushed: 2026-07-02 -> 2026-12-02
2026-07-24 NCT06320717
AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic…
date change Completion pushed: 2026-07-02 -> 2026-12-02
2026-07-22 NCT04348747
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain…
date change Primary completion pushed: 2027-06-15 -> 2028-05-15
2026-07-22 NCT04348747
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain…
date change Completion pushed: 2027-12-15 -> 2028-05-15
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-08-04 NCT07745023 Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality… Not Yet Recruiting
2026-07-22 NCT07718672 Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative… Phase 2 Not Yet Recruiting
2026-07-20 NCT07714018 Comparing Two Weight Loss Programs for the Prevention of Kidney Cancer Progression Among… Not Yet Recruiting
Active Trials by Phase
Phase 4
1
Phase 3
1
Phase 2
25
Phase 1/2
8
Phase 1
12
Early Phase 1
3
Not specified
35
Active Trials — top 25 of 85
NCT IDTitleConditionStatus
Phase 4
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men… Localized Prostate Carcinoma Recruiting
Phase 3
NCT06563388 Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic… Oligometastasis Recruiting
Phase 2
NCT04696575 Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage… Extensive Stage Lung Small Cell Carcinoma Recruiting
NCT05651594 Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment… Clinical Stage II Esophageal Adenocarcinoma AJCC v8 Recruiting
NCT04682158 Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma Esophageal Adenocarcinoma Recruiting
NCT06627751 Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory… Extramedullary Disease in Multiple Myeloma Recruiting
NCT06995508 Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing… Cancer-Associated Anorexia Recruiting
NCT04919629 APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab… Fallopian Tube Carcinosarcoma Recruiting
NCT06821997 NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal… Borderline Resectable Pancreatic Ductal Adenocarcinoma Recruiting
NCT06434064 Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With… Anatomic Stage III Breast Cancer AJCC v8 Recruiting
NCT04068649 Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients… Metastatic Malignant Neoplasm Recruiting
NCT06733363 A Cruciferous Vegetable Eating Program for the Reduction of Cancer Recurrence and… Non-Muscle Invasive Bladder Carcinoma Recruiting
NCT04067830 Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients… Stage I Lung Cancer AJCC v8 Recruiting
NCT06202066 Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients… Digestive System Neuroendocrine Neoplasm Recruiting
NCT06863402 Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse… Richter Syndrome Recruiting
NCT04348747 Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain… Anatomic Stage IV Breast Cancer AJCC v8 Recruiting
NCT07017829 GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11… Advanced Lung Non-Small Cell Carcinoma Recruiting
NCT05231122 Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for… Ovarian Clear Cell Adenocarcinoma Recruiting
NCT04269213 CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60… Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Active, Not Recruiting
NCT04032418 Pembrolizumab Every 12 Weeks Versus Every 3 Weeks in Treating Patients With Non-small… Lung Non-Small Cell Carcinoma Active, Not Recruiting
NCT03899987 Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With… Prostate Adenocarcinoma Active, Not Recruiting
NCT06943664 Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory… Lung Non-Small Cell Carcinoma Not Yet Recruiting
NCT07543172 CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non… Advanced Lung Non-Small Cell Carcinoma Not Yet Recruiting
NCT07718672 Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative… Early Stage Lung Non-Small Cell Carcinoma Not Yet Recruiting
NCT04876248 Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients… Plasma Cell Myeloma Active, Not Recruiting
See all 85 active Roswell Park Cancer Institute trials with filters →
Disease Areas
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