| Detected | Trial | Change |
|---|---|---|
| 2026-08-06 | NCT06816108 A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors |
Enrollment closed, study ongoing |
| 2026-08-06 | NCT06816108 A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors |
Enrollment reduced: 60 -> 35 participants |
| 2026-08-05 | NCT06622941 Study to ONO-4538 in Patients With Rhabdoid Tumor |
Trial sites expanded: 5 -> 14 locations |
| 2026-07-30 | NCT07104032 IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary… |
Trial sites expanded: 20 -> 27 locations |
| 2026-07-30 | NCT06622226 A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma |
critical Trial terminated |
| 2026-07-30 | NCT06622226 A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma |
critical Trial terminated: Sponsor decided to discontinue development of the compound |
| 2026-07-30 | NCT06622226 A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma |
Enrollment reduced: 24 -> 2 participants |
| 2026-07-30 | NCT06622226 A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma |
date change Primary completion moved earlier: 2027-07-31 -> 2026-04-28 |
| 2026-07-30 | NCT06622226 A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma |
date change Completion moved earlier: 2029-12-31 -> 2026-04-28 |
| 2026-07-21 | NCT06696716 ONO-4059 Study in Patients With Steroid-resistant Pemphigus |
overall status: Recruiting → Active, Not Recruiting |
| 2026-07-21 | NCT07618377 Study of DCC-2618 in Patients With GIST After at Least 3 Prior Treatments |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-08-06 | NCT07749768 A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414… | Phase 1 | Not Yet Recruiting |
| 2026-07-29 | NCT07734116 A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients… | Phase 1/2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06579573 | ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures. | Epilepsy, Generalized | Recruiting |
| NCT07594158 | A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With… | Partial Epilepsy | Recruiting |
| NCT07429266 | INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With… | Polycythemia Vera | Recruiting |
| NCT07104032 | IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary… | Relapsed/Refractory Primary Central Nervous System Lymphoma | Recruiting |
| NCT05144854 | A Study to Evaluate the Efficacy and Safety of ONO-4538 in Combination With Ipilimumab… | Gastric Cancer | Active, Not Recruiting |
| NCT06696716 | ONO-4059 Study in Patients With Steroid-resistant Pemphigus | Pemphigus | Active, Not Recruiting |
| Phase 2 | |||
| NCT04566380 | ONO-4538 Phase II Rollover Study (ONO-4538-98) | Pan-tumor | Recruiting |
| NCT06590896 | Safety of Cenobamate in Japanese Subjects With Partial Onset Seizures | Epilepsies, Partial | Recruiting |
| NCT06803823 | A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease… | Agitation Associated With Alzheimer's Disease Dementia | Recruiting |
| NCT06948448 | A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®… | Colorectal Cancer | Recruiting |
| NCT06622941 | Study to ONO-4538 in Patients With Rhabdoid Tumor | Rhabdoid Tumor | Recruiting |
| NCT05923866 | A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy | Multiple System Atrophy (MSA) | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT07734116 | A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients… | Pediatric Malignant Solid Tumor and Epithelioid Sarcoma | Not Yet Recruiting |
| Phase 1 | |||
| NCT06547528 | A Phase I Study to Investigate the Tolerability and Safety of ONO-4685 Given as… | Relapsed or Refractory T Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Recruiting |
| NCT07619157 | A Study of ONO-3310 in Healthy Adult Male Subjects and Chronic Kidney Disease Patients… | Type2 Diabetes Mellitus | Recruiting |
| NCT07618377 | Study of DCC-2618 in Patients With GIST After at Least 3 Prior Treatments | Gastrointestinal Stromal Tumors | Recruiting |
| NCT06542731 | An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With… | Non-small Cell Lung Cancer | Active, Not Recruiting |
| NCT06547385 | Study of ONO-4578 and XELOX/FOLFOX Plus Bevacizumab in Colorectal Cancer | Colorectal Cancer | Active, Not Recruiting |
| NCT06540261 | The Study of ONO-7913, ONO-4538 and the Standard of Care as First-line Treatment in… | Unresectable Colorectal Cancer | Active, Not Recruiting |
| NCT06532344 | An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified… | Metastatic Pancreatic Cancer | Active, Not Recruiting |
| NCT06532331 | A PhaseⅠStudy of ONO-7475 in Combination With ONO-4538 and Gemcitabine Plus… | Metastatic Pancreatic Cancer | Active, Not Recruiting |
| NCT06541665 | Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined… | Primary Central Nervous System Lymphoma | Active, Not Recruiting |
| NCT03155061 | Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid… | Advanced or Metastatic Solid Tumors | Active, Not Recruiting |
| NCT06548217 | A Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid Tumors | Advanced or Metastatic Solid Tumors | Active, Not Recruiting |
| NCT06816108 | A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors | Solid Tumor | Active, Not Recruiting |