37 active trials 16 recruiting 8 Phase 3 18 disease areas 9 changes in 30 days
6 trials changed in the last 30 days: 0 stopped, 2 with notable changes, 4 with minor changes only.
Primary and study completion pushed from Dec 31, 2026 to Jun 30, 2027
Ono Pharmaceutical Co., Ltd.Phase 1 NCT06532344 Registry history of NCT06532344 on ClinicalTrials.gov (opens the registry)
Updated
Primary endpoint(s) modified
Also in this update: Results posted: Oct 6, 2026
Ono Pharmaceutical Co., Ltd.Phase 2 NCT05923866 Registry history of NCT05923866 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Ono Pharmaceutical Co., Ltd.Phase 1 NCT05079282 Registry history of NCT05079282 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Ono Pharmaceutical Co., Ltd.Phase 1 NCT06547528 Registry history of NCT06547528 on ClinicalTrials.gov (opens the registry)
Updated
Trial sites expanded: 10 → 17 locations
Ono Pharmaceutical Co., Ltd.Phase 3 NCT07429266 Registry history of NCT07429266 on ClinicalTrials.gov (opens the registry)
Updated
Trial sites expanded: 9 → 15 locations
Also in this update: Start date pushed from Aug 18, 2026 to Sep 15, 2026
Ono Pharmaceutical Co., Ltd.Phase 1/2 NCT07734116 Registry history of NCT07734116 on ClinicalTrials.gov (opens the registry)
Updated
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-09-22 | NCT07832747 A Study of DCC-3014 to Evaluate the Efficacy, Safety, and Pharmacokinetics in Subjects… | Phase 2 | Not Yet Recruiting |
| 2026-09-17 | NCT07825402 A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System… | Phase 3 | Not Yet Recruiting |
| 2026-09-16 | NCT07823790 ONO-4915 in Patients With Primary Sjogren's Disease | Phase 2 | Not Yet Recruiting |
| 2026-09-14 | NCT07818070 A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in… | Phase 3 | Not Yet Recruiting |
| Phase 1 | 15 | |
| Phase 1/2 | 1 | |
| Phase 2 | 12 | |
| Phase 3 | 8 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 3 | ||||
| NCT07594158 | A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With… | Partial Epilepsy | Recruiting | 2026-10-09 |
| NCT07429266 | INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With… | Polycythemia Vera | Recruiting | 2026-10-05 |
| NCT07104032 | IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary… | Relapsed/Refractory Primary Central Nervous System Lymphoma | Recruiting | 2026-10-01 |
| NCT06579573 | ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures. | Epilepsy, Generalized | Recruiting | 2025-06-17 |
| NCT07825402 | A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System… | Multiple System Atrophy, Parkinson Variant | Not Yet Recruiting | 2026-09-17 |
| NCT07818070 | A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in… | Gastric Cancer | Not Yet Recruiting | 2026-09-14 |
| NCT06696716 | ONO-4059 Study in Patients With Steroid-resistant Pemphigus | Pemphigus | Active, Not Recruiting | 2026-07-20 |
| NCT05144854 | A Study to Evaluate the Efficacy and Safety of ONO-4538 in Combination With Ipilimumab… | Gastric Cancer | Active, Not Recruiting | 2026-06-25 |
| Phase 2 | ||||
| NCT06803823 | A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease… | Agitation Associated With Alzheimer's Disease Dementia | Recruiting | 2026-09-25 |
| NCT06622941 | Study to ONO-4538 in Patients With Rhabdoid Tumor | Rhabdoid Tumor | Recruiting | 2026-08-04 |
| NCT06948448 | A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®… | Colorectal Cancer | Recruiting | 2026-07-16 |
| NCT06936943 | ONO-4538 Study in Patients With Richter's Transformation | Richter's Transformation | Recruiting | 2026-02-13 |
| NCT04566380 | ONO-4538 Phase II Rollover Study (ONO-4538-98) | Pan-tumor | Recruiting | 2025-06-03 |
| NCT06590896 | Safety of Cenobamate in Japanese Subjects With Partial Onset Seizures | Epilepsies, Partial | Recruiting | 2025-06-03 |
| NCT05923866 | A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy | Multiple System Atrophy (MSA) | Active, Not Recruiting | 2026-10-06 |
| NCT07832747 | A Study of DCC-3014 to Evaluate the Efficacy, Safety, and Pharmacokinetics in Subjects… | Tenosynovial Giant Cell Tumor | Not Yet Recruiting | 2026-09-22 |
| NCT07823790 | ONO-4915 in Patients With Primary Sjogren's Disease | Sjogren's Disease | Not Yet Recruiting | 2026-09-16 |
| NCT06881836 | A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease | Alzheimer Disease | Active, Not Recruiting | 2026-08-31 |
| NCT04947319 | Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma… | Refractory Primary Central Nervous System Lymphoma | Active, Not Recruiting | 2026-03-30 |
| NCT06256328 | A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab… | Gastric Cancer | Active, Not Recruiting | 2026-03-13 |
| Phase 1/2 | ||||
| NCT07734116 | A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients… | Pediatric Malignant Solid Tumor and Epithelioid Sarcoma | Recruiting | 2026-10-06 |
| Phase 1 | ||||
| NCT07749768 | A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414… | Ulcerative Colitis (UC) | Recruiting | 2026-09-09 |
| NCT07787208 | A Study of ONO-7429 in Participants With Unresectable Advanced or Recurrent Solid Tumors | Solid Tumors | Recruiting | 2026-08-26 |
| NCT07618377 | Study of DCC-2618 in Patients With GIST After at Least 3 Prior Treatments | Gastrointestinal Stromal Tumors | Recruiting | 2026-07-20 |
| NCT07619157 | A Study of ONO-3310 in Healthy Adult Male Subjects and Chronic Kidney Disease Patients… | Type2 Diabetes Mellitus | Recruiting | 2026-06-08 |
Colorectal Cancer (3) · Gastric Cancer (3) · Non-Small Cell Lung Cancer (NSCLC) (3) · Alzheimer's Disease (2) · Epilepsy (2) · Lung Cancer (2) · Non-Hodgkin Lymphoma (2) · Pancreatic Cancer (2) · Chronic Kidney Disease (1) · Chronic Lymphocytic Leukemia (CLL) (1)