Sponsor pipeline

Novartis Pharmaceuticals clinical trial pipeline

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361 active trials 185 recruiting 91 Phase 3 10 disease areas 92 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 37 of 92 changes on 20 trials

2026-08-08
Withdrawn before enrolling
Trial withdrawn: Sponsor decision
Enrollment reduced: 150 → 0 participants
NCT06431750 Prospective Observational Study to Evaluate Secukinumab Treatment Effectiveness in…
2026-08-22
Primary completion pushed: 2027-06-22 → 2027-09-21
Trial sites reduced: 156 → 147 locations
NCT05126277 Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC… · Phase 3
2026-08-21
Primary completion pushed: 2027-09-16 → 2032-04-05
NCT02386800 CINC424A2X01B Rollover Protocol · Phase 4
2026-08-22
Primary completion pushed: 2026-08-28 → 2026-12-31
NCT06382051 Modifying PEST for Psoriatic Arthritis Screening
2026-08-15
Primary completion pushed: 2025-03-31 → 2025-10-31
Sponsor changed: Novartis → Novartis Pharmaceuticals
Trial completed
Completion pushed: 2025-03-31 → 2025-10-31
NCT06604897 Effectiveness of Entresto (Sacubitril/Valsartan) in Japanese Patients With Hypertension
2026-08-21
Primary endpoint(s) modified
NCT07441642 A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in… · Phase 2
2026-08-19
Primary endpoint(s) modified
Trial sites reduced: 23 → 17 locations
Trial arms changed: 2 → 3
NCT05067140 A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer · Phase 1/2
2026-08-28
Enrollment closed, study ongoing
NCT06462469 Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV… · Phase 4
2026-08-27
Recruitment opened
NCT07775924 A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in… · Phase 2
2026-08-22
Trial completed
NCT04179175 Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term… · Phase 3
2026-08-22
Enrollment closed, study ongoing
Trial sites reduced: 69 → 66 locations
NCT06991556 An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult… · Phase 2
2026-08-13
Enrollment closed, study ongoing
Trial sites reduced: 125 → 116 locations
NCT06517758 A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared… · Phase 3
2026-08-13
Recruitment opened
NCT05776927 A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate /… · Phase 3
2026-08-28
Primary completion pushed: 2028-12-11 → 2029-01-26
Completion pushed: 2028-12-11 → 2029-01-26
NCT07117214 A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers · Phase 1
2026-08-08
Recruitment opened
NCT07642557 Remibrutinib in Real-world Clinical Practice - a Germany Sub-study (REASSERT)
2026-08-01
Enrollment closed, study ongoing
Enrollment increased: 600 → 683 participants
Primary completion moved earlier: 2027-03-11 → 2026-12-23
Completion moved earlier: 2027-03-11 → 2026-12-23
NCT05274425 A 24-week rPMS Study in Real-world Setting for Enerzair
2026-08-19
Primary completion pushed: 2028-04-01 → 2028-05-09
Trial sites expanded: 5 → 9 locations
Completion pushed: 2030-08-10 → 2030-09-13
NCT07421167 A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice… · Phase 2
2026-08-27
Enrollment increased: 360 → 400 participants
NCT06846281 Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants… · Phase 3
2026-07-30
Primary completion pushed: 2031-03-14 → 2031-05-28
Completion pushed: 2044-03-14 → 2044-05-28
NCT06910813 DFT383 in Pediatric Participants With Nephropathic Cystinosis · Phase 1/2
2026-08-28
Trial sites expanded: 49 → 53 locations
NCT07357727 A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF) · Phase 3

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-08-25 NCT07786077 A Study of Patients' Preferences for Primary Immune Thrombocytopenia Treatment Recruiting
2026-08-24 NCT07783503 A Drug-drug Interaction Study to Assess the Effect of Phenytoin and Itraconazole on the… Phase 1 Not Yet Recruiting
2026-08-21 NCT07779460 A Study Comparing Effectiveness of Kesimpta® (Ofatumumab) Versus Ocrevus® (Ocrelizumab)… Recruiting
2026-08-20 NCT07775924 A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in… Phase 2 Recruiting
2026-08-18 NCT07770074 A Real-World Study of Second-line Therapies Among Radioiodine-refractory Differentiated… Not Yet Recruiting
2026-08-17 NCT07767877 A Study of Clinical Practice and Real-world Care of Patients Treated With mTOR, PI3K, and… Not Yet Recruiting
2026-08-17 NCT07767890 A Study of the Safety and Effectiveness of Onasemnogene Abeparvovec (Zolgensma)… Not Yet Recruiting
2026-08-17 NCT07768371 A 52-week Study of Remibrutinib in IgE-mediated Food Allergy Phase 3 Not Yet Recruiting
2026-08-12 NCT07760714 A Real-World Study of Treatment Patterns, Tolerability and Effectiveness of CDK4/6… Completed
2026-08-11 NCT07757048 A Study of Treatment Patterns and Real-World Outcomes in IgA Nephropathy Patients in the… Completed

Active trials by phase

Phase 1
40
Phase 1/2
27
Phase 2
67
Phase 2/3
2
Phase 3
89
Phase 4
25
Not charted: 111 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 361

NCT IDTitleConditionStatusUpdated
Phase 4
NCT03340506 Dabrafenib and/or Trametinib Rollover Study Melanoma Recruiting 2026-08-25
NCT04638647 Secukinumab Open Label Roll-over Extension Protocol Autoimmunity, Inflammation Recruiting 2026-08-18
NCT07489573 Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to… Hidradenitis Suppurativa (HS) Recruiting 2026-08-18
NCT04877522 Asciminib Roll-over Study Chronic Myelogenous Leukemia Recruiting 2026-07-06
NCT04480853 Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing… Multiple Sclerosis Recruiting 2026-06-26
NCT04657822 Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior… Sickle Cell Disease Recruiting 2026-06-08
NCT06824103 Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With… Graft vs. Host Disease Recruiting 2026-06-08
NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate… Prostate Cancer Recruiting 2026-06-04
NCT06733922 ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS Relapsing Remitting Multiple Sclerosis (RRMS) Recruiting 2026-05-15
NCT07034690 Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in… Atherosclerotic Cardiovascular Disease Recruiting 2026-05-04
NCT06501443 LATAM LOWERS LDL-C Hypercholesterolaemia Recruiting 2025-12-30
NCT03975829 Pediatric Long-Term Follow-up and Rollover Study Diffuse Astrocytoma Active, Not Recruiting 2026-08-27
NCT06462469 Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV… Steroid-refractory Acute Graft Versus Host Disease Active, Not Recruiting 2026-08-27
NCT05622708 A Study of Secukinumab to Evaluate Maintenance of Response in Participants With… Non-radiographic Axial Spondyloarthritis Active, Not Recruiting 2026-08-21
NCT02386800 CINC424A2X01B Rollover Protocol Primary Myelofibrosis Active, Not Recruiting 2026-08-20
NCT06444113 Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of… Multiple Sclerosis Active, Not Recruiting 2026-08-12
NCT06372925 Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute… Plaque, Atherosclerotic Active, Not Recruiting 2026-07-28
NCT07713602 Study to Assess Safety and Clinical Responses With Coartem® Baby Dispersible Tablets in… Malaria Not Yet Recruiting 2026-07-20
NCT07684469 Comparative Assessment of Inclisiran on Top of Standard of Care Versus Standard of Care… Acute Coronary Syndrome Not Yet Recruiting 2026-07-06
NCT05161195 Roll-over Study to Allow Continued Access to Ribociclib Metastatic Breast Cancer Active, Not Recruiting 2026-06-23
NCT02584933 Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib… ALK Positive Malignancies Active, Not Recruiting 2026-06-11
NCT05252585 A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous… Renal Angiomyolipoma Active, Not Recruiting 2026-06-11
NCT05090371 A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After… Relapsing-Remitting Multiple Sclerosis Active, Not Recruiting 2026-05-29
NCT06941792 Inclisiran Effectiveness in China: a Pragmatic Randomized Trial Coronary Heart Disease Active, Not Recruiting 2026-05-29
NCT07448610 ASsessing The REAl-world Safety & Effectiveness of Spinal Muscular Atrophy Participants… Spinal Muscular Atrophy Not Yet Recruiting 2026-05-29
See all 361 active Novartis Pharmaceuticals trials with filters →

Disease areas by active trials

Breast Cancer (32) · Multiple Sclerosis (25) · Leukemia (25) · Prostate Cancer (25) · Non-Small Cell Lung Cancer (NSCLC) (16) · Lung Cancer (15) · Hidradenitis Suppurativa (15) · Heart Disease (11) · Lupus (SLE) (10) · Acute Lymphoblastic Leukemia (ALL) (7)

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