| Detected | Trial | Change |
|---|---|---|
| 2026-08-15 | NCT07489495 A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell… |
Trial sites expanded: 69 -> 78 locations |
| 2026-08-15 | NCT03742895 Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated… |
Primary endpoint(s) modified |
| 2026-08-15 | NCT06824467 A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870)… |
Trial sites expanded: 187 -> 191 locations |
| 2026-08-15 | NCT07519772 A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008) |
Trial sites expanded: 30 -> 34 locations |
| 2026-08-15 | NCT07348237 A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006) |
date change Primary completion pushed: 2026-08-18 -> 2026-09-21 |
| 2026-08-15 | NCT07348237 A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006) |
date change Completion pushed: 2026-08-18 -> 2026-09-21 |
| 2026-08-15 | NCT07318558 A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer… |
Trial sites expanded: 144 -> 151 locations |
| 2026-08-15 | NCT04736706 A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and… |
Enrollment increased: 1653 -> 1854 participants |
| 2026-08-15 | NCT04736706 A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and… |
date change Primary completion moved earlier: 2026-10-29 -> 2026-02-04 |
| 2026-08-15 | NCT04736706 A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and… |
date change Completion pushed: 2026-10-29 -> 2027-04-22 |
| 2026-08-13 | NCT04665037 Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal… |
date change Primary completion pushed: 2026-12-16 -> 2027-03-31 |
| 2026-08-13 | NCT04665037 Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal… |
date change Completion pushed: 2026-12-31 -> 2027-04-15 |
| 2026-08-11 | NCT07486960 Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015) |
Trial sites expanded: 46 -> 50 locations |
| 2026-08-11 | NCT07489495 A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell… |
Trial sites expanded: 66 -> 69 locations |
| 2026-08-11 | NCT05382325 A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In… |
date change Primary completion pushed: 2026-07-31 -> 2026-09-30 |
| 2026-08-11 | NCT05382325 A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In… |
date change Completion pushed: 2026-07-31 -> 2026-09-30 |
| 2026-08-11 | NCT07513376 A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated… |
Trial sites expanded: 46 -> 56 locations |
| 2026-08-11 | NCT07218029 A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension… |
Trial sites expanded: 129 -> 132 locations |
| 2026-08-08 | NCT06430801 A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants… |
Primary endpoint(s) modified |
| 2026-08-08 | NCT07519772 A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008) |
Primary endpoint(s) modified |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-08-05 | NCT07748351 A Clinical Trial of Multiple Formulations of MK-4082 in Healthy Overweight and Obese… | Phase 1 | Not Yet Recruiting |
| 2026-08-03 | NCT07743151 A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008) | Phase 1 | Not Yet Recruiting |
| 2026-08-03 | NCT07743164 A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in… | Phase 3 | Not Yet Recruiting |
| 2026-07-29 | NCT07734610 A Clinical Trial of Nemtabrutinib in Participants With Severe Kidney Disease (MK-1026-027) | Phase 1 | Not Yet Recruiting |
| 2026-07-23 | NCT07722611 A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025) | Phase 2/3 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07600723 | A Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) in… | Pulmonary Arterial Hypertension | Not Yet Recruiting |
| Phase 3 | |||
| NCT06351631 | A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017) | Thrombocythemia, Essential | Recruiting |
| NCT06651281 | Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With… | Crohn Disease | Recruiting |
| NCT06345729 | A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS… | Non-small Cell Lung Cancer | Recruiting |
| NCT07013487 | A Study to Evaluate V181 Dengue Vaccine in Healthy Participants 2 to 17 Years of Age… | Healthy | Recruiting |
| NCT06136624 | Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003) | Prostate Cancer Metastatic | Recruiting |
| NCT03486873 | Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who… | Solid Tumors | Recruiting |
| NCT06170788 | Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab… | Non-small Cell Lung Cancer (NSCLC) | Recruiting |
| NCT06077760 | A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus… | Non-small Cell Lung Cancer | Recruiting |
| NCT07227402 | A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer… | Renal Cell Carcinoma | Recruiting |
| NCT06952504 | A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab… | Endometrial Cancer | Recruiting |
| NCT05947851 | A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line… | Leukemia, Lymphocytic, Chronic, B-Cell | Recruiting |
| NCT06136559 | A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib… | Chronic Lymphocytic Leukemia | Recruiting |
| NCT06393374 | Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not… | Triple-Negative Breast Cancer | Recruiting |
| NCT06422143 | Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in… | Non-small Cell Lung Cancer | Recruiting |
| NCT06430801 | A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants… | Crohn's Disease | Recruiting |
| NCT06997497 | A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People… | Colon Adenocarcinoma | Recruiting |
| NCT07190248 | A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With… | Non-small Cell Lung Cancer | Recruiting |
| NCT07216703 | A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab… | Cervical Cancer | Recruiting |
| NCT07554339 | A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell… | Non-small Cell Lung Cancer | Recruiting |
| NCT06623422 | A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in… | Carcinoma, Non-Small-Cell Lung | Recruiting |
| NCT07218029 | A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension… | Pulmonary Arterial Hypertension | Recruiting |
| NCT07405164 | Extension Study for Participants in Studies That Include Belzutifan… | Von Hippel-Lindau Disease | Recruiting |
| NCT06136650 | A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA)… | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Recruiting |
| NCT07431827 | MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC… | Non-small Cell Lung Cancer | Recruiting |