Sponsor pipeline

Karuna Therapeutics clinical trial pipeline

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8 active trials 8 recruiting 6 Phase 3 2 disease areas 6 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-11

What changed in the last 30 days

4 trials changed in the last 30 days: 0 stopped, 2 with notable changes, 2 with minor changes only.

Show 2 trials with minor changes only
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Active trials by phase

Phase 1
1
Phase 3
6
Phase 4
1

Active trials

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07681076 Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in… Healthy Volunteers Recruiting 2026-09-18
Phase 3
NCT05980949 Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in… Psychosis Associated With Alzheimer's Disease Recruiting 2026-09-29
NCT07686263 Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia Schizophrenia Recruiting 2026-09-28
NCT06585787 A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's… Alzheimer Disease Recruiting 2026-09-22
NCT07424404 A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium… Schizophrenia Recruiting 2026-09-22
NCT06126224 A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… Psychosis Associated With Alzheimer's Disease Recruiting 2026-09-04
NCT05511363 A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… Psychosis Associated With Alzheimer's Disease Recruiting 2026-08-17
Phase 1
NCT07204418 A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of… Healthy Volunteers Recruiting 2026-02-19

Disease areas by active trials

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