Sponsor pipeline

Karuna Therapeutics clinical trial pipeline

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8 active trials 6 recruiting 6 Phase 3 2 disease areas 3 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-18
critical
Primary endpoint(s) modified
NCT05511363 A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… · Phase 3
2026-08-01
notable
Trial completed
Trial sites reduced: 175 → 94 locations
NCT05304767 An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in… · Phase 3

Active trials by phase

Phase 1
1
Phase 3
6
Phase 4
1

Active trials

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07681076 Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in… Healthy Volunteers Not Yet Recruiting 2026-07-02
Phase 3
NCT06585787 A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's… Alzheimer Disease Recruiting 2026-08-26
NCT05511363 A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… Psychosis Associated With Alzheimer's Disease Recruiting 2026-08-17
NCT07424404 A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the… Schizophrenia Recruiting 2026-08-13
NCT06126224 A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… Psychosis Associated With Alzheimer's Disease Recruiting 2026-07-30
NCT05980949 Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in… Psychosis Associated With Alzheimer's Disease Recruiting 2026-07-06
NCT07686263 Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia Schizophrenia Not Yet Recruiting 2026-07-07
Phase 1
NCT07204418 A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of… Healthy Volunteers Recruiting 2026-02-19

Disease areas by active trials

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