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Incyte clinical trial pipeline

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60 active trials 30 recruiting 22 Phase 3 10 disease areas 13 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-11
critical
Primary completion pushed: 2026-07-03 → 2027-01-06
Enrollment closed, study ongoing
Completion pushed: 2027-12-31 → 2028-07-20
NCT06843408 A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or… · Phase 1/2
2026-08-26
critical
Primary endpoint(s) modified
NCT07124078 A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants… · Phase 2
2026-08-13
critical
Enrollment reduced: 186 → 37 participants
Enrollment closed, study ongoing
NCT06313593 A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With… · Phase 1
2026-08-11
notable
Enrollment reduced: 225 → 160 participants
Enrollment closed, study ongoing
NCT05936359 A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With… · Phase 1
2026-08-07
notable
Recruitment opened
Trial sites expanded: 0 → 180 locations
NCT07623200 A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With… · Phase 3
2026-08-07
minor
Trial sites expanded: 178 → 181 locations
NCT07214779 Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants… · Phase 3
2026-08-07
minor
Trial sites expanded: 215 → 219 locations
NCT07522073 A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS… · Phase 3
2026-08-20
minor
Completion moved earlier: 2028-05-18 → 2027-09-06
NCT06832618 A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and… · Phase 3

Active trials by phase

Phase 1
16
Phase 1/2
6
Phase 2
13
Phase 3
22
Not charted: 3 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 60

NCT IDTitleConditionStatusUpdated
Phase 3
NCT06585774 A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic… Chronic Graft-versus-host-disease Recruiting 2026-08-06
NCT06855498 Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib Hidradenitis Suppurativa (HS) Recruiting 2026-08-06
NCT07214779 Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants… Ovarian Cancer Recruiting 2026-08-06
NCT07284849 A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and… CRC (Colorectal Cancer) Recruiting 2026-08-06
NCT07522073 A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS… Solid Tumors Recruiting 2026-08-06
NCT07623200 A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With… Essential Thrombocythemia Recruiting 2026-08-06
NCT06548360 A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric… NonSegmental Vitiligo Recruiting 2026-07-23
NCT06804811 A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12… NonSegmental Vitiligo Recruiting 2026-07-22
NCT06615050 A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant… Graft-versus-host Disease (GVHD) Recruiting 2026-05-20
NCT06113445 A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental… NonSegmental Vitiligo Active, Not Recruiting 2026-08-25
NCT06212999 A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants… Hidradenitis Suppurativa (HS) Active, Not Recruiting 2026-08-25
NCT06821542 A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic… Chronic Graft-versus-host-disease Active, Not Recruiting 2026-08-25
NCT06832618 A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and… Atopic Dermatitis Active, Not Recruiting 2026-08-19
NCT06959225 Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With… Hidradenitis Suppurativa Active, Not Recruiting 2026-07-28
NCT06958211 Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With… Hidradenitis Suppurativa Active, Not Recruiting 2026-07-08
NCT06516952 A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With… Prurigo Nodularis Active, Not Recruiting 2026-05-28
NCT05429268 Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in… Large B-Cell Lymphoma Active, Not Recruiting 2026-05-05
NCT06516965 A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With… Prurigo Nodularis Active, Not Recruiting 2026-04-14
NCT04824092 Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate… Diffuse Large B-cell Lymphoma Active, Not Recruiting 2026-04-01
NCT06113471 A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental… NonSegmental Vitiligo Active, Not Recruiting 2026-03-31
NCT06263478 A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy… Chronic Graft-versus-host-disease Active, Not Recruiting 2026-01-07
NCT04680052 A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and… Follicular Lymphoma Active, Not Recruiting 2025-12-22
Phase 2
NCT07124078 A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants… Chronic Graft-versus-host-disease Recruiting 2026-08-25
NCT07023627 A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin… Ovarian Cancer Recruiting 2026-08-06
NCT07104565 Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With… Immune Thrombocytopenia Recruiting 2026-08-06

Disease areas by active trials

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