Sponsor Pipeline

Roche / Genentech Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-07-21
249
Active Trials
111
Recruiting
89
Phase 3
10
Disease Areas
91
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-07-21 NCT05949580
Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care…
Recruitment suspended
2026-07-21 NCT05949580
Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care…
critical why stopped: null → "Transition of study Sponsor."
2026-07-21 NCT07282574
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of…
Trial sites expanded: 91 -> 103 locations
2026-07-21 NCT07351058
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With…
Trial sites expanded: 122 -> 163 locations
2026-07-21 NCT07351045
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With…
Trial sites expanded: 128 -> 164 locations
2026-07-21 NCT05775289
A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus…
Trial completed
2026-07-21 NCT05775289
A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus…
date change Completion moved earlier: 2026-06-01 -> 2026-04-30
2026-07-21 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
Trial sites expanded: 7 -> 15 locations
2026-07-21 NCT07541079
A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant…
Recruitment opened
2026-07-19 NCT07214766
A Study to Assess the Bioequivalence of Trastuzumab Via Different Subcutaneous Delivery…
Trial completed
2026-07-19 NCT06723106
Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)
Trial sites expanded: 58 -> 62 locations
2026-07-19 NCT06723106
Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)
date change Primary completion pushed: 2027-04-30 -> 2028-02-28
2026-07-19 NCT06723106
Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)
date change Completion pushed: 2027-04-30 -> 2028-02-28
2026-07-17 NCT07158242
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121)…
Trial sites expanded: 12 -> 15 locations
2026-07-17 NCT05296798
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo…
Trial sites reduced: 206 -> 202 locations
2026-07-17 NCT07239336
Study of DONQ52 in Active Celiac Disease
Trial sites expanded: 56 -> 62 locations
2026-07-16 NCT04158258
A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients…
date change Primary completion pushed: 2026-06-30 -> 2026-07-31
2026-07-16 NCT04158258
A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients…
date change Completion pushed: 2026-06-30 -> 2026-07-31
2026-07-16 NCT06780150
A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain…
Primary endpoint(s) modified
2026-07-16 NCT05123703
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in…
Primary endpoint(s) modified
Showing 20 of 91 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-26 NCT07670416 A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or… Phase 3 Recruiting
2026-06-25 NCT07667322 A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and… Phase 1 Recruiting
2026-06-24 NCT07665723 An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's… Phase 1 Recruiting
Active Trials by Phase
Phase 4
11
Phase 3
85
Phase 2/3
4
Phase 2
50
Phase 1/2
26
Phase 1
51
Not specified
22
Active Trials — top 25 of 249
NCT IDTitleConditionStatus
Phase 4
NCT05861986 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early… Muscular Atrophy, Spinal Recruiting
NCT06274515 A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies Breast Cancer Recruiting
NCT05861999 A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric… Muscular Atrophy, Spinal Recruiting
NCT04853251 A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related… Neovascular Age-related Macular Degeneration Recruiting
NCT05181618 A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants… Severe Hemophilia A Active, Not Recruiting
NCT06795048 A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants… Neovascular Age-related Macular Degeneration (nAMD) Active, Not Recruiting
NCT07025811 A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants… Dry Eye Disease Active, Not Recruiting
NCT05224102 A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented… Diabetic Macular Edema Active, Not Recruiting
NCT07483450 A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of… Relapsing Multiple Sclerosis Active, Not Recruiting
NCT07609719 A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple… Multiple Sclerosis Not Yet Recruiting
NCT05232929 Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA) Spinal Muscular Atrophy Active, Not Recruiting
Phase 3
NCT06675955 An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and… Multiple Sclerosis Recruiting
NCT06094010 A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants… Influenza Recruiting
NCT05797610 A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants… Primary IgA Nephropathy Recruiting
NCT06847542 A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD Neovascular Age-related Macular Degeneration Recruiting
NCT05894239 A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo… Metastatic Breast Cancer Recruiting
NCT05878769 A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic… Chronic Obstructive Pulmonary Disease Recruiting
NCT06084936 A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in… Lymphoma Recruiting
NCT06588855 A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also… Moderately to Severely Active Ulcerative Colitis Recruiting
NCT06790693 A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and… Breast Cancer Recruiting
NCT06819878 A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With… Moderately to Severely Active Crohns Disease Recruiting
NCT07169578 A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease Alzheimers Disease Recruiting
NCT03683251 Extension Study for the Port Delivery System With Ranibizumab (Portal) Neovascular Age-Related Macular Degeneration Recruiting
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a… Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Recruiting
NCT06819891 A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart… Moderately to Severely Active Crohns Disease Recruiting
View all 249 active Roche / Genentech trials with filters →
Disease Areas
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