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Bristol-Myers Squibb clinical trial pipeline

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226 active trials 113 recruiting 71 Phase 3 46 disease areas 61 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 41 of 61 changes on 20 trials

2026-10-02
Trial terminated
Trial terminated: Inability to meet protocol objectives
Trial sites reduced: 16 → 10 locations
Final enrollment: 34 participants (planned 105)
Primary completion confirmed: August 2026 (last estimated February 2027)
NCT06419634 Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With… · Phase 1
2026-09-19
Reclassified as terminated (was completed)
Trial terminated: Trial terminated because of lack of efficacy in the short term acute phase
NCT05582395 A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy · Phase 3
2026-09-23
Primary completion pushed: 2026-03-13 → 2027-02-16
NCT06140836 A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or… · Phase 3
2026-09-19
Primary completion pushed: 2036-11-30 → 2043-05-29
Trial sites expanded: 213 → 222 locations
Completion pushed: 2036-11-30 → 2043-05-29
NCT03435796 Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells · Phase 2/3
2026-09-12
Primary completion pushed: 2024-02-06 → 2024-11-07
NCT04908189 A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in… · Phase 3
2026-09-10
Primary completion pushed: 2026-12-01 → 2028-01-31
Completion pushed: 2026-12-01 → 2028-01-31
NCT06875960 A Study to Continue the Administration of Deucravacitinib in Participants With Systemic… · Phase 4
2026-09-23
Primary endpoint(s) modified
Results posted: 2026-09-22
NCT04810078 A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With… · Phase 3
2026-09-19
Primary endpoint(s) modified
Enrollment increased: 130 → 182 participants
Interventions modified
Trial sites reduced: 70 → 67 locations
Trial arms changed: 2 → 4
NCT06855771 A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab… · Phase 2
2026-10-02
Recruitment opened
NCT07763418 A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With… · Phase 1
2026-10-02
Trial completed
Study completion confirmed: February 2026 (last estimated March 2026)
NCT07458542 Effectiveness and Safety of ONUREG (Oral Azacitidine) in Chinese Patients With Acute…
2026-10-02
Trial completed
NCT07571148 Real-world Patient Characteristics, Treatment Patterns, and Healthcare Utilization Among…
2026-10-01
Trial completed
NCT06971185 A Study to Evaluate Treatment Patterns and Effectiveness of Luspatercept
2026-09-25
Recruitment opened
Trial sites expanded: 1 → 6 locations
NCT07780383 A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and… · Phase 1
2026-09-25
Trial completed
Primary completion confirmed: September 2026 (last estimated May 2027)
NCT06799286 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy… · Phase 1
2026-09-11
Trial completed
NCT04036435 Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in… · Phase 3
2026-09-11
Trial completed
Study completion confirmed: April 2026 (last estimated December 2027)
NCT03661320 A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and… · Phase 3
2026-09-09
Enrollment closed, study ongoing
Trial sites reduced: 281 → 212 locations
NCT06764485 A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice… · Phase 3
2026-09-22
Trial completed
Final enrollment: 69 participants (planned 24)
NCT07248839 A Study to Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal… · Phase 1
2026-09-11
Enrollment closed, study ongoing
Trial sites reduced: 36 → 31 locations
NCT05664737 A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to… · Phase 2
2026-09-25
Primary completion pushed: 2026-07-18 → 2026-09-28
Trial sites reduced: 207 → 204 locations
NCT05552976 A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone… · Phase 3

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-10-01 NCT07852884 First-Line Systemic Therapies in Advanced Renal Cell Carcinoma in Spain Active, Not Recruiting
2026-10-01 NCT07852962 Study to Assess Drug Levels, Immune Response, Safety and Tolerability of BMS-986446 in… Phase 1 Not Yet Recruiting
2026-09-30 NCT07848295 A Study to Assess the Safety and Tolerability of BMS-986527 in Participants With Clear… Phase 1 Not Yet Recruiting
2026-09-29 NCT07846059 Evaluation of Mavacamten-Based Practice in Chinese Adults With Obstructive Hypertrophic… Not Yet Recruiting
2026-09-23 NCT07837115 A Study to Assess the Relative Bioavailability of Irafamdastat (BMS-986368) and to Assess… Phase 1 Not Yet Recruiting
2026-09-02 NCT07800897 A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy… Phase 1 Not Yet Recruiting

Active trials by phase

Phase 1
32
Phase 1/2
23
Phase 2
23
Phase 2/3
11
Phase 3
60
Phase 4
7
Not charted: 70 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 226

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06875960 A Study to Continue the Administration of Deucravacitinib in Participants With Systemic… Systemic Lupus Erythematosus (SLE) Recruiting 2026-09-09
NCT07221877 A Study to Evaluate the Effect of KarXT on Urological Safety Schizophrenia Recruiting 2026-06-03
NCT06112743 A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With… Cardiomyopathy, Hypertrophic Active, Not Recruiting 2026-09-16
NCT05891249 A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of… Anemia Active, Not Recruiting 2026-08-31
NCT07459543 A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose… Unresectable Melanoma Not Yet Recruiting 2026-08-12
NCT07004972 A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India… Symptomatic Obstructive Hypertrophic Cardiomyopathy Active, Not Recruiting 2026-04-28
NCT06396039 A Study to Assess the Effectiveness and Safety of Ozanimod in Chinese Adults With… Relapsing Multiple Sclerosis Active, Not Recruiting 2025-04-16
Phase 3
NCT05519085 A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus… Relapsed or Refractory Multiple Myeloma Recruiting 2026-09-30
NCT07361497 A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation… Non-small Cell Lung Cancer (NSCLC) Recruiting 2026-09-30
NCT07361510 A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With… Non-Small Cell Lung Cancer (NSCLC) Recruiting 2026-09-30
NCT06937229 A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in… Alzheimer Disease Recruiting 2026-09-28
NCT06951711 A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes… Bipolar Disorder Type I With Mania or Mania With Mixed Features Recruiting 2026-09-24
NCT06561386 A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs… Non-small Cell Lung Cancer Recruiting 2026-09-23
NCT06951698 A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes… Bipolar-I Disorder With Mania or Mania With Mixed Features Recruiting 2026-09-22
NCT07116967 Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With… Plaque Psoriasis Recruiting 2026-09-22
NCT06976203 A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment… Alzheimer's Disease Recruiting 2026-09-17
NCT07011732 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment… Alzheimer Disease Recruiting 2026-09-16
NCT07011745 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment… Alzheimer's Disease Recruiting 2026-09-16
NCT06615479 A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in… Relapsed or Refractory Multiple Myeloma (RRMM) Recruiting 2026-09-15
NCT06929273 A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in… Bipolar Disorder Type I With Mania Recruiting 2026-09-14
NCT06646276 A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed… Extensive-Stage Small Cell Lung Cancer Recruiting 2026-09-11
NCT06408259 Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in… Multiple Sclerosis, Relapsing-Remitting Recruiting 2026-09-10
NCT07288567 A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia… Schizophrenia Recruiting 2026-09-04
NCT06979453 A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165)… Plaque Psoriasis Recruiting 2026-09-03
NCT04877288 A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney… Renal Allograft Recipients Recruiting 2026-08-31
See all 226 active Bristol-Myers Squibb trials with filters →

Disease areas by active trials, top 10 of 46

Lung Cancer (26) · Non-Small Cell Lung Cancer (NSCLC) (23) · Multiple Myeloma (17) · Psoriasis (14) · Alzheimer's Disease (9) · Multiple Sclerosis (9) · Myelodysplastic Syndromes (MDS) (9) · Lupus (SLE) (8) · Melanoma (8) · Non-Hodgkin Lymphoma (8)

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