| Detected | Trial | Change |
|---|---|---|
| 2026-08-13 | NCT06822790 Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia |
Trial sites reduced: 294 -> 255 locations |
| 2026-08-13 | NCT07037771 A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial… |
Enrollment closed, study ongoing |
| 2026-08-13 | NCT07037771 A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial… |
Enrollment increased: 60 -> 70 participants |
| 2026-07-24 | NCT06880770 Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute… |
Trial sites expanded: 95 -> 102 locations |
| 2026-07-23 | NCT07662096 A First-In-Human Study of ARO-033 in Adult Participants |
Recruitment opened |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06880770 | Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute… | Severe Hypertriglyceridemia | Recruiting |
| NCT06822790 | Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia | Hypertriglyceridemia | Recruiting |
| NCT07473843 | Study of Zodasiran in Adolescent Participants With Homozygous Familial… | Homozygous Familial Hypercholesterolemia | Not Yet Recruiting |
| NCT06347133 | Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia | Hypertriglyceridemia | Active, Not Recruiting |
| NCT06347003 | Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia | Severe Hypertriglyceridemia | Active, Not Recruiting |
| NCT06347016 | Study of Plozasiran in Adults With Severe Hypertriglyceridemia | Severe Hypertriglyceridemia | Active, Not Recruiting |
| NCT07037771 | A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial… | Homozygous Familial Hypercholesterolemia | Active, Not Recruiting |
| Phase 2 | |||
| NCT07241546 | Study of Inhaled ARO-RAGE in Allergen-induced Mild Asthma | Asthma | Recruiting |
| Phase 1/2 | |||
| NCT07221344 | Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's… | Alzheimer Disease | Recruiting |
| NCT06700538 | A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2… | Obesity | Recruiting |
| NCT06937203 | A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2… | Obesity | Recruiting |
| NCT07223658 | Study of ARO-DIMERPA in Adult Participants With Mixed Hyperlipidemia | Hyperlipidemia; Mixed | Recruiting |
| Phase 1 | |||
| NCT07662096 | A First-In-Human Study of ARO-033 in Adult Participants | Healthy Participants | Recruiting |
| NCT06672445 | Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 2 | Active, Not Recruiting |