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Akeso clinical trial pipeline

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84 active trials 40 recruiting 23 Phase 3 22 disease areas 4 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days

2026-09-30
notable
NCT07700979 Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination… · Phase 3

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-29 NCT07847281 A Study of AK157D1 for Injection in Advanced Solid Tumors Phase 1 Not Yet Recruiting

Active trials by phase

Phase 1
17
Phase 1/2
19
Phase 2
24
Phase 3
23
Not charted: 1 active trial with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 84

NCT IDTitleConditionStatusUpdated
Phase 3
NCT07700979 Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination… Gastric / Gastroesophageal Junction Adenocarcinoma Recruiting 2026-09-29
NCT07412613 Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch… Resectable Colon Cancer Recruiting 2026-04-22
NCT06928389 Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer Non-Small Cell Lung Cancer Recruiting 2026-04-09
NCT06767527 AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally… Triple-Negative Breast Cancer (TNBC) Recruiting 2026-03-16
NCT07010263 A Study of AK112 as Consolidation Treatment for Patients With Limited Stage Small-cell… Small Cell Lung Cancer Recruiting 2026-03-05
NCT06951503 AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer Colorectal Adenocarcinoma Recruiting 2026-03-04
NCT06953999 A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic… Pancreatic Cancer Recruiting 2026-03-04
NCT07023315 A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for… Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma Recruiting 2026-02-11
NCT05489289 A Phase III Study of AK104 as Adjuvant Therapy in HCC With High Risk of Recurrence After… Hepatocellular Carcinoma Recruiting 2025-03-12
NCT06371157 A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE)… Hepatocellular Carcinoma Recruiting 2025-03-12
NCT06617416 A Study of AK104 in Subjects With Unresectable Locally Advanced NSCLC NSCLC (Non-small Cell Lung Cancer) Recruiting 2025-03-12
NCT06601335 A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head… Head and Neck Squamous Cell Carcinoma Recruiting 2024-11-14
NCT06341335 A Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal… Gastric and Gastroesophageal Junction Adenocarcinoma Recruiting 2024-06-24
NCT05499390 AK112 in Advanced Non-Small Cell Lung Cancer Advanced Non-small-cell Lung Cancer Active, Not Recruiting 2026-03-09
NCT05184712 Phase 3 Clinical Study of AK112 for NSCLC Patients Non-Squamous Non-small Cell Lung Cancer Active, Not Recruiting 2026-03-04
NCT07449780 A Study of AK104 (SC) in Combination With Oxaliplatin and Capecitabine (XELOX) Versus… Gastric / Gastroesophageal Junction Adenocarcinoma Not Yet Recruiting 2026-03-04
NCT06591520 AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced… Biliary Tract Cancer Active, Not Recruiting 2026-01-21
NCT04982237 A Study of AK104 Plus Platinum-containing Chemotherapy±Bevacizumab as First-line… Cervical Cancer Active, Not Recruiting 2025-11-19
NCT05840016 AK112 in Combination With Chemotherapy in Advanced Squamous Non-Small Cell Lung Cancer Advanced Squamous Non Small Cell Lung Cancer Active, Not Recruiting 2025-05-02
NCT04974398 A Study of Penpulimab (AK105) in the First-line Treatment of Recurrent or Metastatic… Nasopharyngeal Carcinoma Active, Not Recruiting 2025-04-13
NCT06767540 A Clinical Study of AK120 in Adolescents With Moderate-to-severe Atopic Dermatitis Atopic Dermatitis Not Yet Recruiting 2025-01-10
NCT05235516 A Study of AK104/Placebo Combined With Chemoradiotherapy For The Treatment of Locally… Locally Advanced Cervical Carcinoma Active, Not Recruiting 2024-08-13
NCT05990127 A Study of AK104/Tislelizumab With Chemotherapy as First-line Treatment in PD-L1 TPS < 1%… Locally Advanced or Metastatic NSCLC Not Yet Recruiting 2023-08-14
Phase 2
NCT07591090 A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast Cancer Advanced Breast Cancer Recruiting 2026-07-22
NCT07669779 A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung… Advanced Non Small Cell Lung Cancer (NSCLC) Recruiting 2026-07-14

Disease areas by active trials, top 10 of 22

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