Drug Pipeline

Tarlatamab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
22
Active Studies
14
Recruiting
5
Phase 3
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-21 NCT06898957
Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death…
Enrollment reduced: 200 -> 29 participants
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-09 NCT07637513 Tarlatamab and Durvalumab vs. Durvalumab Alone for Limited-Stage-Small Cell Lung Cancer Phase 3 Not Yet Recruiting
Active Studies by Phase
Phase 3
5
Phase 2
9
Phase 1/2
2
Phase 1
6
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT06937905 Tarlatamab vs Standard of Care Chemotherapy in Patients With Pre-treated Advanced… Neuroendocrine Carcinoma Recruiting
NCT07005128 A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab… Small-cell Lung Cancer Recruiting
NCT05740566 Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung… Small Cell Lung Cancer (SCLC) Active, Not Recruiting
NCT06117774 Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung… Limited Stage Small Cell Lung Cancer Active, Not Recruiting
NCT07637513 Tarlatamab and Durvalumab vs. Durvalumab Alone for Limited-Stage-Small Cell Lung Cancer Limited Stage Small-Cell Lung Cancer Not Yet Recruiting
Phase 2
NCT07061080 Refractory Advanced diGestive Neuroendocrine Carcinomas Treated With tARlatamab Advanced Neuroendocrine Carcinomas of The Digestive System Recruiting
NCT07423585 Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer Extensive Stage Lung Small Cell Carcinoma Recruiting
NCT06893783 Efficacy and Safety Evaluation of Tarlatamab in Advanced Extrapulmonary Neuroendocrine… Neuroendocrine Carcinomas (NEC) Recruiting
NCT07111507 A Study of Tarlatamab for People With Prostate Cancer Metastatic Prostate Cancer Recruiting
NCT07242547 Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage… Limited-stage Small-cell Lung Cancer Recruiting
NCT07203053 A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer… Extensive Stage Lung Small Cell Cancer Recruiting
NCT06745323 A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in… Small Cell Lung Cancer (SCLC) Active, Not Recruiting
NCT06502977 Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer… Extensive Stage Small Cell Lung Cancer Active, Not Recruiting
NCT07402343 Tarlatamab for SCLC Brain Metastases Small Cell Lung Cancer Not Yet Recruiting
Phase 1/2
NCT06814496 Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors Melanoma Recruiting
NCT07243470 Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors Glioma Recruiting
Phase 1
NCT06551142 A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD) Neoplasms Recruiting
NCT06598306 Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer… Extensive Stage Small Cell Lung Cancer Recruiting
NCT07037758 A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage… Extensive Stage Small Cell Lung Cancer Recruiting
NCT07531095 Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small… Small Cell Lung Cancer Recruiting
NCT05361395 First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in… Extensive Stage Small Cell Lung Cancer Active, Not Recruiting
NCT06898957 Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death… Small Cell Lung Cancer Active, Not Recruiting
Sponsors Running Tarlatamab Trials
Disease Areas
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