| Detected | Trial | Change |
|---|---|---|
| 2026-06-09 | NCT07483177 HEART: Pilot Randomized Controlled Trial |
Recruitment opened |
| 2026-06-06 | NCT04582383 Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne |
date change Completion pushed: 2026-07-31 -> 2027-07-31 |
| 2026-05-19 | NCT06678685 Spironolactone Improved Children With Gene Mutations Related to NCOR |
date change Primary completion pushed: 2025-10-30 -> 2026-12-30 |
| 2026-05-19 | NCT06678685 Spironolactone Improved Children With Gene Mutations Related to NCOR |
date change Completion pushed: 2025-10-30 -> 2027-12-30 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07281014 | Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing | Heart Failure | Recruiting |
| NCT07523867 | Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety Study | Heart Failure | Not Yet Recruiting |
| NCT04582383 | Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne | Acne | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT06678685 | Spironolactone Improved Children With Gene Mutations Related to NCOR | NCOR Gene Mutations | Recruiting |
| Phase 2 | |||
| NCT03593317 | Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD | Arrhythmogenic Right Ventricular Dysplasia | Recruiting |
| NCT07041281 | Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories | Preeclampsia | Recruiting |
| NCT07304817 | Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein… | CKD | Recruiting |
| NCT01712620 | Spironolactone for Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension | Recruiting |
| NCT06004830 | Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1 | Alcohol Use Disorder | Active, Not Recruiting |
| NCT07539259 | To Establish Whether Dapagliflozin and Spironolactone in Patients With Severe Aortic… | Aortic Stenosis | Not Yet Recruiting |
| Phase 1/2 | |||
| NCT07483177 | HEART: Pilot Randomized Controlled Trial | Thoracic Aortic Aneurysm | Recruiting |
| NCT07431216 | A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of… | Glioblastoma (GBM) | Not Yet Recruiting |
| Phase 1 | |||
| NCT05807139 | Spironolactone in Alcohol Use Disorder (SAUD) | Alcohol Use Disorder | Recruiting |
| Not specified | |||
| NCT07328230 | Superselective Adrenal Arterial Embolization Versus Oral Spironolactone for Treatment of… | Idiopathic Hyperaldosteronism | Recruiting |
| NCT07415811 | Spironolactone and XPB-1 Integrity in the TFIIH Complex | HIV | Enrolling by Invitation |
| NCT07585526 | Safety and Efficacy of Finerenone in Metabolic Dysfunction Associated Steatotic Liver… | MASLD | Not Yet Recruiting |