Clinical Trial

HEART: Pilot Randomized Controlled Trial

Recruiting Phase 1/2
View on ClinicalTrials.gov →
Summary
The purpose of this study is to determine whether spironolactone reduces aortic stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), compared with placebo, in patients with degenerative thoracic aortic aneurysms.
Protocol Amendment History 1 change
critical Recruitment opened 2026-06-09
Trial Details
NCT Number NCT07483177
Lead Sponsor Mayo Clinic
Conditions Thoracic Aortic Aneurysm
Enrollment 50 participants
Start Date 2026-05-25
Primary Completion 2028-05 (estimated)
Study Completion 2028-05 (estimated)
Updated on ClinicalTrials.gov 2026-06-08