Drug Pipeline

Rilvegostomig Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
27
Active Studies
21
Recruiting
12
Phase 3
3
Top Sponsors
5
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT06921785
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without…
Trial sites expanded: 217 -> 220 locations
2026-05-28 NCT07098338
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
Trial sites expanded: 64 -> 83 locations
2026-05-28 NCT07431281
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in…
Trial sites expanded: 258 -> 269 locations
2026-05-23 NCT06564844
A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or…
Trial sites reduced: 99 -> 90 locations
2026-05-15 NCT06467357
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary…
Trial sites expanded: 266 -> 270 locations
Active Studies by Phase
Phase 3
12
Phase 2
8
Phase 1/2
3
Phase 1
3
Early Phase 1
1
Active Trials — top 25 of 27
NCT IDTitleConditionStatus
Phase 3
NCT07221253 A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of… Biliary Tract Cancer Recruiting
NCT06989112 DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or… Endometrial Cancer Recruiting
NCT06764875 A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab… HER2-positive Gastric Cancer Recruiting
NCT06467357 Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary… Biliary Tract Cancer Recruiting
NCT06868277 A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line… Carcinoma, Non-Small Cell Lung Recruiting
NCT06357533 Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for… Non-Small Cell Lung Cancer Recruiting
NCT06627647 A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for… Non-squamous Non-small Cell Lung Cancer Recruiting
NCT07431281 Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in… Gastric Cancer Recruiting
NCT06692738 A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for… Non-small Cell Lung Cancer Recruiting
NCT06921785 Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without… Hepatocellular Carcinoma Recruiting
NCT06109779 Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection… Biliary Tract Cancer Active, Not Recruiting
NCT06564844 A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or… Non-small Cell Lung Cancer Active, Not Recruiting
Phase 2
NCT05414032 Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and… Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC) Recruiting
NCT05489211 Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients… Endometrial Cancer Recruiting
NCT05775159 Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents… Hepatocellular Carcinoma Recruiting
NCT05702229 Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic… Gastric Cancer Recruiting
NCT07069712 A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With… Gastroesophageal Adenocarcinoma Recruiting
NCT05061550 Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer Non-small Cell Lung Cancer Recruiting
NCT07098338 A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC) Non-Small Cell Lung Cancer Recruiting
NCT04379596 Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing… Gastric Cancer Recruiting
Phase 1/2
NCT06996782 A Platform Study in Non-Small Cell Lung Cancer (NSCLC) Advanced or Metastatic Non-small Cell Lung Cancer Recruiting
NCT07115043 A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or… Melanoma Recruiting
NCT04995523 A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced… Non-Small-Cell Lung Carcinoma Active, Not Recruiting
Phase 1
NCT04686305 Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without… Locally Advanced or Metastatic Non-Small Cell Lung Cancer Recruiting
NCT04612751 Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin… Advanced or Metastatic NSCLC Active, Not Recruiting
Sponsors Running Rilvegostomig Trials
Disease Areas
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