Sponsor Pipeline

AstraZeneca Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
488
Active Trials
247
Recruiting
161
Phase 3
10
Disease Areas
125
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT06749457
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and…
date change Primary completion pushed: 2026-11-30 -> 2027-04-02
2026-06-12 NCT06749457
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and…
date change Completion pushed: 2027-09-09 -> 2028-01-07
2026-06-12 NCT06921785
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without…
Trial sites expanded: 217 -> 220 locations
2026-06-12 NCT07391657
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA)…
Trial sites expanded: 111 -> 116 locations
2026-06-12 NCT05647122
First in Human Study of AZD9592 in Solid Tumors
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-12 NCT05647122
First in Human Study of AZD9592 in Solid Tumors
Enrollment reduced: 403 -> 167 participants
2026-06-12 NCT05647122
First in Human Study of AZD9592 in Solid Tumors
Trial sites reduced: 51 -> 46 locations
2026-06-12 NCT07052578
Aggressive Disease Treatment Patterns and CtDNA HRR evaluatiON in High-volume metastatiC…
Trial sites expanded: 18 -> 22 locations
2026-06-12 NCT07052578
Aggressive Disease Treatment Patterns and CtDNA HRR evaluatiON in High-volume metastatiC…
date change Primary completion pushed: 2028-06-30 -> 2028-11-30
2026-06-12 NCT07052578
Aggressive Disease Treatment Patterns and CtDNA HRR evaluatiON in High-volume metastatiC…
date change Completion pushed: 2028-06-30 -> 2028-11-30
2026-06-12 NCT07446738
A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative…
date change Primary completion pushed: 2027-08-30 -> 2027-10-21
2026-06-12 NCT07446738
A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative…
date change Completion pushed: 2027-08-30 -> 2027-10-21
2026-06-11 NCT07608354
A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and…
Primary endpoint(s) modified
2026-06-11 NCT06706817
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic…
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-11 NCT06706817
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic…
Trial sites reduced: 45 -> 41 locations
2026-06-11 NCT07455825
A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of…
Trial completed
2026-06-11 NCT07044336
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial…
Enrollment increased: 700 -> 800 participants
2026-06-11 NCT07044336
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial…
Trial sites expanded: 314 -> 317 locations
2026-06-11 NCT07044336
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial…
date change Primary completion moved earlier: 2028-01-20 -> 2027-10-15
2026-06-10 NCT06097728
MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural…
overall status: "Recruiting" → "Active Not Recruiting"
Showing 20 of 125 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-08 NCT07633158 Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the… Not Yet Recruiting
2026-06-05 NCT07630714 A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous… Phase 2 Not Yet Recruiting
2026-06-03 NCT07622433 A Phase I, Cross-over Study Comparing the Relative Bioavailability of Laroprovstat Plus… Phase 1 Not Yet Recruiting
2026-06-03 NCT07624305 A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With… Phase 3 Not Yet Recruiting
2026-06-03 NCT07624318 Trop2 NMR Concordance Study Not Yet Recruiting
2026-06-01 NCT07617636 Observational Study That Will Analyse the Spread and Stratification of Lung Cancer Risk… Not Yet Recruiting
2026-06-01 NCT07619118 A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With… Phase 3 Not Yet Recruiting
2026-06-01 NCT07619131 A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With… Phase 3 Not Yet Recruiting
2026-05-29 NCT07612813 A Study to Evaluate the Safety and Pharmacokinetics of AZD7760 in Healthy Japanese Adults Phase 1 Not Yet Recruiting
2026-05-29 NCT07613424 A Study of MET Concordance and Gene Profiling in 1L NSCLC (Genomet) Not Yet Recruiting
Active Trials by Phase
Phase 4
13
Phase 3
160
Phase 2/3
1
Phase 2
68
Phase 1/2
45
Phase 1
61
Not specified
140
Active Trials — top 25 of 488
NCT IDTitleConditionStatus
Phase 4
NCT07306949 Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association… Transthyretin-type Cardiac Amyloidosis Recruiting
NCT07221838 A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia… Generalized Myasthenia Gravis Recruiting
NCT06531798 Post-marketing Phase 4 Safety & Tolerability Study of Breztri aerosphereTM in Indian… Moderate to Severe COPD Recruiting
NCT07308574 Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS aHUS Recruiting
NCT06594068 Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in… Systemic Lupus Erythematosus Recruiting
NCT06651970 Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL… Chronic Lymphocytic Leukaemia Recruiting
NCT07279935 Osimertinib Combined With Chemotherapy in Patients Who Had Distant Recurrence After… Non-small Cell Lung Cancer Recruiting
NCT07073950 A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate… Chronic Obstructive Pulmonary Disease Recruiting
NCT07357597 An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd)… Stomatitis Not Yet Recruiting
NCT06610526 A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease Chronic Kidney Disease Active, Not Recruiting
NCT06422689 Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on… Asthma Active, Not Recruiting
NCT05457257 Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With… Metastatic Castration-resistant Prostate Cancer Active, Not Recruiting
NCT03953300 Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics Asthma Active, Not Recruiting
Phase 3
NCT07218809 AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low… Epithelial Ovarian Cancer Recruiting
NCT07024563 Study of Ravulizumab in Pediatric Participants With Primary IgAN IgAN Recruiting
NCT07221253 A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of… Biliary Tract Cancer Recruiting
NCT06607627 PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+… Generalized Myasthenia Gravis Recruiting
NCT06291376 Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN) Immunoglobulin A Nephropathy Recruiting
NCT07007793 A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary… Primary Hyperaldosteronism Recruiting
NCT06307652 Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure… Heart Failure and Impaired Kidney Function Recruiting
NCT06830798 Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy… Delayed Graft Function Recruiting
NCT06103864 A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's… Breast Cancer Recruiting
NCT06350097 Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab… Non-small Cell Lung Cancer Recruiting
NCT06989112 DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or… Endometrial Cancer Recruiting
NCT06878261 A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With… Chronic Obstructive Pulmonary Disease (COPD) Recruiting
View all 488 active AstraZeneca trials with filters →
Disease Areas
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