Disease landscape

Asthma clinical trials

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643 active trials 355 recruiting 58 Phase 3 390 sponsors 111 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 48 of 111 changes on 20 trials

2026-08-12
Trial status changed: Completed → Terminated
Trial terminated: Sponsor Decision
NCT06376045 A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma · Amgen · Phase 2
2026-08-08
Withdrawn before enrolling
Trial withdrawn: PI departure from institution
Enrollment reduced: 50 → 0 participants
NCT07044388 Coping With Asthma Throughout Life Management Program · Duke University
2026-08-08
Primary completion pushed: 2026-10-30 → 2027-10-04
Enrollment increased: 790 → 1000 participants
Completion pushed: 2026-10-30 → 2027-10-04
NCT06471257 A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic… · AstraZeneca · Phase 3
2026-08-20
Primary completion pushed: 2025-09-30 → 2027-09-30
Completion pushed: 2025-11-30 → 2028-11-30
NCT05111262 Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily… · Washington University School of Medicine · Phase 1/2
2026-08-21
Primary completion pushed: 2026-02-19 → 2028-02-19
Completion pushed: 2026-03-19 → 2028-03-19
NCT05691218 Early High-flow Oxygen Therapy With nebuLized Beta-2-agonist Using a Vibrating Mesh for… · Poitiers University Hospital
2026-08-12
Primary completion pushed: 2026-07-31 → 2026-12-31
Completion pushed: 2026-12-31 → 2027-06-30
NCT06223828 Azithromycin for Critical Asthma - Pediatrics · Johns Hopkins All Children's Hospital · Phase 2/3
2026-08-07
Primary completion pushed: 2026-07 → 2027-12
Completion pushed: 2026-09 → 2028-06
NCT04743791 Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects… · Sally E. Wenzel MD · Phase 4
2026-08-18
Primary completion pushed: 2026-07-31 → 2029-07-31
Primary endpoint(s) modified
Completion pushed: 2029-07 → 2029-12-01
NCT07735494 Physical Activity Promotion and Clinical Remission in Severe Asthma · University of Leeds
2026-08-14
Primary completion pushed: 2026-07-01 → 2027-07-01
Primary endpoint(s) modified
Recruitment opened
Completion pushed: 2026-07-01 → 2027-07-01
NCT07345572 Investigating the Impact of Early Time-Restricted Eating on Health Outcomes and Quality… · De Montfort University
2026-08-04
Primary completion pushed: 2028-11 → 2029-11
Recruitment opened
Completion pushed: 2028-11 → 2029-11
NCT07134686 Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of… · Assistance Publique Hopitaux De Marseille
2026-08-01
Primary completion pushed: 2026-03 → 2030-03
Completion pushed: 2028-12 → 2030-12
NCT02351141 Structure and Function MRI of Asthma · Dr. Grace Parraga
2026-08-14
Primary endpoint(s) modified
Trial completed
NCT06465485 STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With… · AstraZeneca · Phase 3
2026-08-20
Primary endpoint(s) modified
NCT07241117 CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma · Washington University School of Medicine · Phase 4
2026-08-08
Primary endpoint(s) modified
Primary completion moved earlier: 2018-11-10 → 2018-10-11
Completion pushed: 2025-02 → 2027-11
NCT01728571 LungVITamin D and OmegA-3 Trial (lungVITAL) · Brigham and Women's Hospital
2026-08-04
Primary endpoint(s) modified
NCT07738016 Artificially Intelligent Robot Control · University of Miami
2026-08-18
Enrollment reduced: 300 → 93 participants
Trial status changed: Enrolling by Invitation → Completed
Completion moved earlier: 2025-12-20 → 2025-02-20
NCT06652542 Asthma Exacerbations & Respiratory Management International Survey · Assiut University
2026-07-30
Enrollment reduced: 26 → 20 participants
Trial completed
NCT06825871 Automated Inhaler Monitoring for Asthma Medication Usage · Boston Children's Hospital
2026-08-27
Recruitment opened
Enrollment increased: 30 → 34 participants
Trial sites expanded: 0 → 3 locations
Primary completion moved earlier: 2029-03-19 → 2027-03-01
Completion moved earlier: 2029-03-19 → 2028-11-24
NCT07671001 A Study of Depemokimab in Participants of 6 to 11 Years of Age · GlaxoSmithKline · Phase 3
2026-08-28
Recruitment opened
NCT07705737 Rademikibart IV for Acute Asthma and COPD Exacerbation · Connect Biopharm LLC · Phase 2
2026-08-20
Recruitment opened
Trial sites expanded: 0 → 45 locations
NCT07444567 Roll-over Study for Participants Who Have Completed a Previous Clinical Study With… · AstraZeneca · Phase 3

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-27 NCT07790159 Budesonide/Formoterol Inhalation Powder in Adults With Asthma Shanghai Xin Huanghe Pharmaceutical Co., Ltd. new Phase 3
2026-08-27 NCT07791147 Family-centred Pulmonary Rehabilitation to Empower Carers Aveiro University new
2026-08-26 NCT07787507 Withania Somnifera for Moderate-to-Severe Persistent Asthma Aligarh Muslim University new
2026-08-26 NCT07788534 This Study Aims to Compare Asthma Control in Children Monitored With FeNO Against a… King Faisal Specialist Hospital & Research Center new
2026-08-17 NCT07768891 Beclometasone Dipropionate and Formoterol Inhalation Aerosol for Asthma Lunan Better Pharmaceutical Co., LTD. new Phase 3
2026-08-14 NCT07765264 Clinical and Autonomic Efficacy of Digital-Gamified Diaphragmatic Training in Pediatric… Delta University for Science and Technology new
2026-08-14 NCT07766460 Predictive Factors for a Positive Exercise Bronchial Hyperresponsiveness Test Central Hospital, Nancy, France new
2026-08-13 NCT07764042 Effects of Wet Cupping Therapy in Patients With Asthma Medipol University new
2026-08-07 NCT07752836 Virtual Breathing Intervention for Enhancing Asthma-related Quality of Life - A… Prof. Dr. Andreas Rembert Koczulla new
2026-08-05 NCT07746687 A Study of JNJ-95597528 in Participants With Inadequately Controlled Moderate to Severe… Johnson & Johnson new Phase 2

Active trials by phase

Early Phase 1
4
Phase 1
22
Phase 1/2
4
Phase 2
70
Phase 2/3
4
Phase 3
54
Phase 4
38
Not charted: 447 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 643

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07241117 CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma Washington University School of Medicine Recruiting 2026-08-19
NCT04743791 Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects… Sally E. Wenzel MD Recruiting 2026-08-06
NCT07666490 BETRI-Prospective: Asthma Control in Single Inhaler ICS/LABA/LAMA (87/5/9 pMDI [BDP/FF/GB… Chiesi Farmaceutici S.p.A. Recruiting 2026-07-31
NCT07228052 Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department Montefiore Medical Center Recruiting 2026-07-24
NCT03889743 Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time… St. Olavs Hospital Recruiting 2026-07-20
NCT06705764 Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA) University of Alberta Recruiting 2026-07-17
NCT07651891 Evaluation of ALLERgen Specific Vaccination of DOG Allergic Patients in Swedish Practice Karolinska Institutet Recruiting 2026-06-29
NCT07426458 Ventilation and Perfusion in Asthmatics University of Miami Recruiting 2026-05-05
NCT07402707 Dosing of Steroids for Acute Asthma Given in the Emergency Department - a Pilot… Sheffield Children's NHS Foundation Trust Recruiting 2026-04-23
NCT07166939 45th Multicenter Airway Research Collaboration Massachusetts General Hospital Recruiting 2026-04-17
NCT07052942 Individualizing Treatment for Asthma in Primary Care (Full Study) DARTNet Institute Recruiting 2025-10-29
NCT06970080 Therapeutic Relevance of Abnormal Airway Morphology in Asthma McMaster University Recruiting 2025-09-11
NCT04380038 Viral Infection in Asthma (VIA) Study University of Virginia Recruiting 2025-04-01
NCT06816342 Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized… Beni-Suef University Recruiting 2025-02-10
NCT04763447 Short Treatment with Omalizumab for Severe Asthma Assistance Publique - Hôpitaux de Paris Recruiting 2024-11-07
NCT06385236 Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping University of California, San Diego Recruiting 2024-08-19
NCT04565483 Predictive Signature of Benralizumab Response Nantes University Hospital Recruiting 2024-04-26
NCT01225913 Mechanism(s) of Airflow Limitation During Exacerbation of Asthma Gelb, Arthur F., M.D. Recruiting 2023-10-26
NCT03953300 Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics AstraZeneca Active, Not Recruiting 2026-08-25
NCT06152653 The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM) University of California, San Francisco Active, Not Recruiting 2026-08-13
NCT07664527 Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate University of Wisconsin, Madison Not Yet Recruiting 2026-07-29
NCT06422689 Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on… AstraZeneca Active, Not Recruiting 2026-07-16
NCT07654842 Fasenra: An Asthma Study Endeavor Health Not Yet Recruiting 2026-07-07
NCT06572228 Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting… Regeneron Pharmaceuticals Active, Not Recruiting 2026-05-22
NCT05097287 Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline… Sanofi Active, Not Recruiting 2026-04-16
See all 643 active Asthma trials with filters →

Top sponsors by active trials in this area

AstraZeneca (31) · GlaxoSmithKline (12) · Henan University of Traditional Chinese Medicine (7) · University of Colorado, Denver (7) · Brigham and Women's Hospital (6) · Chinese University of Hong Kong (6) · Sanofi (6) · Copenhagen Studies on Asthma in Childhood (5) · First Affiliated Hospital of Ningbo University (5) · Guangdong Hengrui Pharmaceutical Co., Ltd (5)

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