CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma

Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Single Maintenance and Reliever Therapy). The investigators will provide training and resources to clinicians, give feedback on prescribing patterns, and offer educational tools for patients and providers. The investigators will roll out these resources in stages across clinics. The study will measure how well the program helps clinicians prescribe SMART therapy and whether it reduces asthma exacerbations in patients.

NCT Number	NCT07241117
Lead Sponsor	Washington University School of Medicine Collaborators: National Heart, Lung, and Blood Institute (NHLBI), Doris Duke Charitable Foundation, Affinia Healthcare, Family Care Health Centers
Conditions	Moderate to Severe Asthma
Enrollment	2,000 participants
Start Date	2026-01-06
Primary Completion	2027-11-15 (estimated)
Study Completion	2028-11-15 (estimated)
Updated on ClinicalTrials.gov	2026-01-16