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Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate

Study acronym: EVOOW
StatusNot Yet Recruiting
PhasePhase 4
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 4 months later across 2 updates Apr 2027 → Sep 2027
See other at-risk trials from University of Wisconsin, Madison

Record History

See every version on ClinicalTrials.gov ↗

  1. Start date pushed from Sep 2026 to Nov 2026 Show 4 more changesShow less
    • Primary endpoints: details revised at 1 of 1 entry
    • Primary and study completion pushed from Jul 2027 to Sep 2027
    • Eligibility criteria expanded, about 8 words
    • Secondary endpoints: details revised at 2 of 2 entries
  2. Primary and study completion pushed from Apr 2027 to Jul 2027
    • Start date: Aug 2026 to Sep 2026
    v4
  3. Start date: Jul 2026 to Aug 2026v3
  4. Start date: Jun 2026 to Jul 2026v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study is to find out if an Extra Virgin Olive-Oil-based Water (EVOOW) mix, removes more Fluticasone Propionate (FP) from the mouth than Water alone. 2 strengths of the EVOOW mix will be tested, one with equal parts EVOO and Water (50/50) and one with 3 parts EVOO and 1 part Water (75/25). Removing more FP deposits may help decrease the risk for obstructive sleep apnea (OSA), candidiasis (thrush), and speech and swallow dysfunction. Participants will be on study for up to 3 weeks.
Trial Details
NCT Number NCT07664527
Lead Sponsor University of Wisconsin, Madison
Conditions
(from sponsor)		 Asthma
Related terms Asthma
Enrollment 20 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov