Drug Pipeline

Fluorouracil Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
141
Active Studies
76
Recruiting
42
Phase 3
10
Top Sponsors
46
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT05647122
First in Human Study of AZD9592 in Solid Tumors
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-12 NCT05647122
First in Human Study of AZD9592 in Solid Tumors
Enrollment reduced: 403 -> 167 participants
2026-06-12 NCT05647122
First in Human Study of AZD9592 in Solid Tumors
Trial sites reduced: 51 -> 46 locations
2026-06-11 NCT05083481
A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab…
Trial terminated
2026-06-11 NCT05083481
A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab…
date change Primary completion moved earlier: 2026-06-30 -> 2026-05-11
2026-06-11 NCT05083481
A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab…
date change Completion moved earlier: 2026-06-30 -> 2026-05-11
2026-06-10 NCT07490301
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With…
Recruitment opened
2026-06-10 NCT07490301
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With…
Trial sites expanded: 0 -> 9 locations
2026-06-09 NCT07566156
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy…
Trial sites expanded: 1 -> 9 locations
2026-06-09 NCT06997497
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People…
Trial sites expanded: 192 -> 196 locations
2026-06-06 NCT06901531
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With…
Trial sites expanded: 238 -> 246 locations
2026-06-06 NCT05891171
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
date change Primary completion pushed: 2026-03 -> 2027-09
2026-06-06 NCT05891171
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
date change Completion pushed: 2026-03 -> 2027-09
2026-06-06 NCT06750094
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in…
Trial sites expanded: 241 -> 247 locations
2026-06-06 NCT05355701
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced…
date change Primary completion moved earlier: 2029-02-02 -> 2028-04-23
2026-06-06 NCT05355701
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced…
date change Completion moved earlier: 2030-08-06 -> 2029-10-25
2026-06-05 NCT05253651
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in…
date change Primary completion pushed: 2026-04-03 -> 2027-12-31
2026-06-05 NCT05253651
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in…
date change Completion pushed: 2029-07-27 -> 2030-07-03
2026-06-03 NCT07456852
Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in…
Recruitment opened
2026-06-03 NCT07456852
Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in…
date change Primary completion pushed: 2028-03-31 -> 2028-04-30
Showing 20 of 46 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-02 NCT07619313 AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients… Phase 1 Not Yet Recruiting
2026-06-02 NCT07621497 FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable… Phase 2 Not Yet Recruiting
2026-06-02 NCT07621718 Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of… Phase 3 Recruiting
2026-05-26 NCT07606599 A Study of BL-M07D1 Versus Physician's Choice of Chemotherapy in Patients With… Phase 3 Not Yet Recruiting
Active Studies by Phase
Phase 4
1
Phase 3
37
Phase 2/3
5
Phase 2
53
Phase 1/2
11
Phase 1
31
Early Phase 1
1
Not specified
2
Active Trials — top 25 of 141
NCT IDTitleConditionStatus
Phase 4
NCT07352566 Utilization of a Microdevice for Psoriasis and Atopic Dermatitis Psoriasis Not Yet Recruiting
Phase 3
NCT06958328 Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma Recruiting
NCT07097142 Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients… Muscle Invasive Bladder Urothelial Carcinoma Recruiting
NCT03801876 Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer Clinical Stage I Esophageal Adenocarcinoma AJCC v8 Recruiting
NCT05677490 mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced… Advanced Esophageal Adenocarcinoma Recruiting
NCT06764875 A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab… HER2-positive Gastric Cancer Recruiting
NCT06998940 Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or… Locally Advanced Pancreatic Adenocarcinoma Recruiting
NCT07431281 Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in… Gastric Cancer Recruiting
NCT07043400 A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus… Metastatic Gastric Adenocarcinoma Recruiting
NCT05863195 Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of… Metastatic Colorectal Carcinoma Recruiting
NCT07409272 A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either… Pancreatic Cancer Recruiting
NCT07621718 Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of… Pancreatic Cancer Recruiting
NCT05253651 A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in… Colorectal Neoplasms Recruiting
NCT06662786 A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI… Colorectal Neoplasms Recruiting
NCT06750094 A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in… Colorectal Neoplasms Recruiting
NCT06901531 A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With… Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer Recruiting
NCT06997497 A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People… Colon Adenocarcinoma Recruiting
NCT07566156 Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy… Urothelial Cancer Recruiting
NCT04340141 Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable… Pancreatic Adenosquamous Carcinoma Active, Not Recruiting
NCT04094688 Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or… Colorectal Adenocarcinoma Active, Not Recruiting
NCT00433420 Combination Chemotherapy With or Without Fluorouracil and/or Pegfilgrastim in Treating… Breast Cancer Active, Not Recruiting
NCT04241185 Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy… Urinary Bladder Neoplasms Active, Not Recruiting
NCT00980460 Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer PRETEXT I Hepatoblastoma Active, Not Recruiting
NCT03504397 A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy… Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer Active, Not Recruiting
NCT04248452 Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients… Clinical Stage IV Esophageal Adenocarcinoma AJCC v8 Active, Not Recruiting
Sponsors Running Fluorouracil Trials
Disease Areas
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