Sponsor Pipeline

Alliance for Clinical Trials in Oncology Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
49
Active Trials
22
Recruiting
29
Phase 3
10
Disease Areas
4
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-06 NCT01953588
Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III…
Primary endpoint(s) modified
2026-06-03 NCT06661720
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab)…
Trial sites expanded: 410 -> 414 locations
2026-06-03 NCT06931340
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy…
Trial sites expanded: 186 -> 194 locations
2026-06-03 NCT06876714
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+…
Trial sites expanded: 631 -> 656 locations
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-05-26 NCT07605364 Testing the Addition of an Anti-Cancer Drug, Mycophenolate Mofetil, to the Usual… Phase 2/3 Not Yet Recruiting
Active Trials by Phase
Phase 3
25
Phase 2/3
4
Phase 2
12
Phase 1/2
1
Not specified
7
Active Trials — top 25 of 49
NCT IDTitleConditionStatus
Phase 3
NCT05677490 mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced… Advanced Esophageal Adenocarcinoma Recruiting
NCT05379153 Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The… Anatomic Stage 0 Breast Cancer AJCC v8 Recruiting
NCT06992427 High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral… Head and Neck Squamous Cell Carcinoma Recruiting
NCT03150693 Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly… B Acute Lymphoblastic Leukemia Recruiting
NCT05008848 Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Cigarette Smoking-Related Carcinoma Recruiting
NCT05673148 Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for… Metastatic Colorectal Adenocarcinoma Recruiting
NCT05976763 Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for… Mantle Cell Lymphoma Recruiting
NCT06632327 Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB… Resectable Lung Non-Small Cell Carcinoma Recruiting
NCT06661720 Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab)… Clear Cell Renal Cell Carcinoma Recruiting
NCT06931340 Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy… Castration-Sensitive Prostate Carcinoma Recruiting
NCT07000084 Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone)… Recurrent Non-Muscle Invasive Bladder Carcinoma Recruiting
NCT05812807 Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a… Anatomic Stage II Breast Cancer AJCC v8 Recruiting
NCT06876714 ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+… Anatomic Stage I Breast Cancer AJCC v8 Recruiting
NCT07321652 Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment… Chronic Lymphocytic Leukemia Not Yet Recruiting
NCT00887146 Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy… Brain and Central Nervous System Tumors Active, Not Recruiting
NCT04455750 A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With… Castration-Resistant Prostate Carcinoma Active, Not Recruiting
NCT04340141 Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable… Pancreatic Adenosquamous Carcinoma Active, Not Recruiting
NCT03414970 Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients… Ductal Breast Carcinoma Active, Not Recruiting
NCT04094688 Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or… Colorectal Adenocarcinoma Active, Not Recruiting
NCT04637594 Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy Locally Advanced Bladder Urothelial Carcinoma Active, Not Recruiting
NCT04939090 Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced… Advanced Malignant Solid Neoplasm Active, Not Recruiting
NCT03927027 Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer… Breast Cancer Stage I Active, Not Recruiting
NCT04114981 Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic… Metastatic Malignant Neoplasm in the Brain Active, Not Recruiting
NCT01905046 Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia… Atypical Ductal Breast Hyperplasia Active, Not Recruiting
NCT01953588 Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III… Estrogen Receptor-positive Breast Cancer Active, Not Recruiting
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Disease Areas
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