| Detected | Trial | Change |
|---|---|---|
| 2026-06-10 | NCT06592924 Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration… |
Trial sites expanded: 340 -> 368 locations |
| 2026-06-05 | NCT07287150 A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant… |
Trial sites expanded: 20 -> 32 locations |
| 2026-06-04 | NCT03344211 Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic… |
date change Primary completion pushed: 2026-11-21 -> 2026-12-31 |
| 2026-06-04 | NCT03344211 Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic… |
date change Completion pushed: 2027-11-21 -> 2027-12-31 |
| 2026-06-04 | NCT06136650 A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA)… |
Trial sites expanded: 324 -> 327 locations |
| 2026-06-03 | NCT07226986 A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan… |
Trial sites expanded: 12 -> 17 locations |
| 2026-05-29 | NCT07028853 This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat… |
Trial sites expanded: 305 -> 329 locations |
| 2026-05-28 | NCT06120491 Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-28 | NCT06120491 Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate… |
Trial sites reduced: 410 -> 322 locations |
| 2026-05-28 | NCT06120491 Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate… |
date change Primary completion moved earlier: 2028-01-11 -> 2027-09-30 |
| 2026-05-23 | NCT07028853 This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat… |
Trial sites expanded: 302 -> 305 locations |
| 2026-05-23 | NCT03860987 Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using… |
Trial completed |
| 2026-05-23 | NCT03860987 Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using… |
date change Primary completion moved earlier: 2026-07-31 -> 2026-05-11 |
| 2026-05-23 | NCT03860987 Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using… |
date change Completion moved earlier: 2028-08-01 -> 2026-05-18 |
| 2026-05-16 | NCT06691984 Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy… |
overall status: "Recruiting" → "Active Not Recruiting" |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-02 | NCT07620574 Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored… | Phase 3 | Not Yet Recruiting |
| 2026-05-28 | NCT07611110 AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant… | Phase 3 | Recruiting |
| 2026-05-18 | NCT07592910 A Study of Mevrometostat With Enzalutamide in People With Prostate Cancer Who Have… | Phase 2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT03016741 | Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer | Castration-Resistant Prostatic Cancer | Active, Not Recruiting |
| NCT05457257 | Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With… | Metastatic Castration-resistant Prostate Cancer | Active, Not Recruiting |
| Phase 3 | |||
| NCT06136624 | Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003) | Prostate Cancer Metastatic | Recruiting |
| NCT06764485 | A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice… | Metastatic Castration-resistant Prostate Cancer | Recruiting |
| NCT06520345 | The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT… | Metastatic Castration-resistant Prostate Cancer | Recruiting |
| NCT07611110 | AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant… | Metastatic Castration-resistant Prostate Cancer | Recruiting |
| NCT06629779 | A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic… | Metastatic Castration-Resistant Prostate Cancer | Recruiting |
| NCT06136650 | A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA)… | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Recruiting |
| NCT06592924 | Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration… | Prostate Cancer (Adenocarcinoma) | Recruiting |
| NCT07028853 | This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat… | Metastatic Castration Sensitive Prostate Cancer (mCSPC) | Recruiting |
| NCT04647526 | Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line… | Metastatic Castration-Resistant Prostate Cancer | Active, Not Recruiting |
| NCT04455750 | A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With… | Castration-Resistant Prostate Carcinoma | Active, Not Recruiting |
| NCT05112965 | An Extension Study in Participants Previously Enrolled in a Genentech and/or F… | Neoplasms | Active, Not Recruiting |
| NCT04076059 | An Efficacy and Safety Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT)… | Metastatic Hormone Sensitive Prostate Cancer | Active, Not Recruiting |
| NCT03768063 | A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd… | Cancer | Active, Not Recruiting |
| NCT06551324 | A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in… | Metastatic Castrate Resistant Prostate Cancer (mCRPC) | Active, Not Recruiting |
| NCT02446444 | Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk… | Prostatic Neoplasms | Active, Not Recruiting |
| NCT02319837 | Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic… | Hormone Sensitive Prostate Cancer | Active, Not Recruiting |
| NCT06691984 | Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy… | Metastatic Castration-resistant Prostate Cancer | Active, Not Recruiting |
| NCT06120491 | Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate… | Metastatic Castration-Sensitive Prostate Cancer | Active, Not Recruiting |
| NCT07620574 | Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored… | Cancer | Not Yet Recruiting |
| Phase 2 | |||
| NCT06059118 | Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic… | Prostate Cancer | Recruiting |
| NCT06099769 | A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy… | Metastatic Breast Cancer | Recruiting |
| NCT05726292 | A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus… | Prostate Cancer | Recruiting |
| NCT05751941 | Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic… | Prostate Cancer | Recruiting |