| Detected | Trial | Change |
|---|---|---|
| 2026-05-29 | NCT07349979 PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF |
Primary endpoint(s) modified |
| 2026-05-29 | NCT07349979 PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF |
Enrollment increased: 654 -> 1154 participants |
| 2026-05-14 | NCT06844669 HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving… |
Trial terminated |
| 2026-05-14 | NCT06844669 HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving… |
critical why stopped: null → "Futility" |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07405944 | Vericiguat and Reverse Remodeling Indices in Heart Failure | Heart Failure With Reduced Ejection Fraction (HFrEF) | Recruiting |
| NCT07521332 | Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis | Cirrhosis | Recruiting |
| NCT07490067 | Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol… | Heart Failure With Reduced Ejection Fraction | Recruiting |
| NCT07322237 | DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With… | Cirrhotic Cardiomyopathy | Recruiting |
| NCT07352228 | Carvedilol vs. Propranolol for Preventing Rebleeding After Endoscopic Treatment of… | Rebleeding of Portal Hypertension in Liver Cirrhosis | Enrolling by Invitation |
| NCT07298993 | Deprescribing Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction… | Heart Failure | Enrolling by Invitation |
| NCT07295522 | Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? | Heart Failure | Not Yet Recruiting |
| NCT05872698 | Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. | Cirrhosis, Liver | Active, Not Recruiting |
| Phase 3 | |||
| NCT05931276 | CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes | End-Stage Kidney Disease | Recruiting |
| NCT07477990 | Clinical Trial to Evaluate the Efficacy and Safety of the Aurora® Digital Medical Device… | General Anxiety Disorder | Recruiting |
| Phase 2/3 | |||
| NCT06128980 | Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced… | Heart Failure With Reduced Ejection Fraction | Recruiting |
| Phase 2 | |||
| NCT02560805 | Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV | Stress Disorders, Post-Traumatic | Recruiting |
| NCT03775096 | Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136) | REM Sleep Behavior Disorder | Active, Not Recruiting |
| NCT04218968 | Cardiac Changes in Early Parkinson's Disease: A Follow up Study | REM Sleep Behavior Disorder | Active, Not Recruiting |
| Early Phase 1 | |||
| NCT06643221 | Exercise as an Immune Adjuvant for Allogeneic Cell Therapies | Leukemia | Recruiting |
| Not specified | |||
| NCT07491718 | Manganese-enhanced Magnetic Resonance Imaging in Takotsubo Cardiomyopathy | Takotsubo Cardiomyopathy | Recruiting |
| NCT07424690 | Catheter Ablation vs Conservative Care in Elderly Patients With Atrial Fibrillation | Atrial Fibrillation (AF) | Not Yet Recruiting |
| NCT07465471 | Carvedilol and Midodrine Versus Carvedilol Alone in Preventing Early Rebleed in Patients… | Liver Cirrhosis | Not Yet Recruiting |
| NCT06126081 | Clinical Efficacy of Early Left Bundle Branch Pacing for Cardiac Resynchronization Therapy | Heart Failure | Active, Not Recruiting |
| NCT07519161 | Pharmacological Intervention to Prevent NOAF After TAVR | Atrial Fibrillation | Not Yet Recruiting |
| NCT07568574 | Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes | Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes | Enrolling by Invitation |
| NCT07560982 | Evaluating Adherence to Guideline-Directed Medical Therapy in Patients With Advanced… | Heart Failure | Not Yet Recruiting |
| NCT05572957 | LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB | Non-ischemic Cardiomyopathy | Active, Not Recruiting |
| NCT07331220 | Pulmonary Artery Denervation for Heart Failure With Preserved Left Ventricular Ejection… | Heart Failure With Preserved Ejection Fraction | Not Yet Recruiting |
| NCT07349979 | PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF | Heart Failure With Reduced Ejection Fraction | Not Yet Recruiting |