Disease landscape

Coronary Artery Disease clinical trials

Get alerts when Coronary Artery Disease trials change

1,119 active trials 582 recruiting 42 Phase 3 593 sponsors 110 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 48 of 110 changes on 20 trials

2026-08-27
Primary completion pushed: 2024-09 → 2026-01-06
Trial status changed: Unknown → Completed
Completion pushed: 2025-02 → 2026-01-06
NCT06009757 GUIDEX® Versus Launcher™ Guiding Catheter in Percutaneous Coronary Intervention (PCI)… · Tianjin Demax Medical Technology Co., Ltd
2026-08-26
Primary completion pushed: 2026-08-01 → 2026-11-01
Completion pushed: 2026-11-01 → 2027-03-01
NCT07407738 ShockFast Intravascular Lithotripsy Device for Treatment of Calcified Coronary Lesions · Shunmei Medical
2026-08-28
Primary completion pushed: 2027-12-01 → 2028-09-01
Enrollment closed, study ongoing
Trial sites expanded: 25 → 32 locations
Completion pushed: 2029-12-01 → 2031-09-01
NCT06218485 FFR Versus IVUS With Angiography-Derived FFR for Clinical Outcomes in Patients With… · Second Affiliated Hospital, Zhejiang University, School of Medicine
2026-08-28
Primary completion pushed: 2026-08 → 2027-08
Completion pushed: 2027-03 → 2028-03
NCT06143332 Domain-specific Aerobic Exercise Training in Coronary Artery Disease · Western University, Canada
2026-08-21
Primary completion pushed: 2025-08 → 2026-03-31
Enrollment closed, study ongoing
NCT06495177 European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease… · European Society of Cardiology
2026-08-27
Primary completion pushed: 2026-03 → 2026-07-04
Trial completed
Completion moved earlier: 2029-11 → 2026-07-04
NCT05500443 The DANish COronary DEcalcification (DANCODE) Trial · Odense University Hospital
2026-07-30
Primary completion pushed: 2026-03-15 → 2027-02
Completion pushed: 2031-02-15 → 2031-12
NCT04545112 Xeltis Coronary Artery Bypass Graft (XABG) First in Human (FIH) · Xeltis
2026-08-22
Primary completion pushed: 2026-10-15 → 2028-12-30
NCT05923489 Routine Angiography Follow-Up After Percutaneous Coronary Intervention in High-Risk… · Second Affiliated Hospital, Zhejiang University, School of Medicine
2026-08-22
Primary completion pushed: 2026-04-01 → 2026-08-13
Enrollment reduced: 200 → 23 participants
Trial completed
Completion moved earlier: 2026-12-01 → 2026-08-13
NCT05609214 Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and… · University of Zurich
2026-08-21
Primary completion pushed: 2027-06-30 → 2029-12-31
Completion pushed: 2030-01-01 → 2030-12-31
NCT03217006 Randomization of Single vs Multiple Arterial Grafts · Weill Medical College of Cornell University
2026-08-06
Primary completion pushed: 2030-08-01 → 2030-11-01
Completion pushed: 2030-10-01 → 2030-12-01
NCT07725484 Efficacy of Lipoic Acid on Chronic Ischemic Heart Failure Patients · Shanghai Zhongshan Hospital · Phase 3
2026-08-20
Primary completion pushed: 2025-07-01 → 2026-05-01
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Completion pushed: 2025-12-31 → 2028-12-31
NCT06565793 A MAajor RAdiation-based PCI Study in STEMI and NSTEMI · Centre Cardiologique du Nord
2026-08-19
Primary completion pushed: 2026-07-01 → 2027-06-30
Completion pushed: 2026-07-01 → 2027-06-30
NCT06143709 Precision PCI Registry · University of Florida
2026-08-15
Primary completion pushed: 2025-05-31 → 2025-10-28
NCT03298659 iFR Guided Multi-vessel Revascularization During Percutaneous Coronary Intervention for… · Radboud University Medical Center
2026-08-13
Primary completion pushed: 2026-03-06 → 2026-08-04
Enrollment closed, study ongoing
Completion pushed: 2026-03-06 → 2026-08-05
NCT05492110 Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed… · Imperial College London
2026-08-12
Primary completion pushed: 2028-02-28 → 2028-12-31
Primary endpoint(s) modified
Enrollment reduced: 380 → 190 participants
Completion pushed: 2029-02-28 → 2029-12-30
Trial arms changed: 2 → 1
NCT07700524 Intraoperative Ultrasound Assessment of Coronary Artery and Bypass Graft Blood Flow… · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
2026-08-06
Primary completion pushed: 2026-05-01 → 2026-12-01
Completion pushed: 2027-05-01 → 2027-12-01
NCT06448637 DRUG RELEASING BALL vs. PHARMACOACTIVE STENT IN LARGE VESSELS: MORPHOLOGICAL ANALYSIS AND… · Fundación EPIC
2026-08-21
Primary endpoint(s) modified
NCT07773064 Identification for High Risk of Coronary Heart Disease Based on Quantitative Analysis of… · Beijing Hospital
2026-08-19
Primary endpoint(s) modified
Trial status changed: Recruiting → Enrolling by Invitation
Completion pushed: 2026-12-01 → 2030-12-01
NCT06620458 Influencing Factors and Outcomes of DCB Angioplasty · Henan Institute of Cardiovascular Epidemiology
2026-08-14
Primary endpoint(s) modified
NCT05418556 Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting… · Asan Medical Center · Phase 4

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-26 NCT07786961 Music Medicine in Coronary Interventional Cardiology Procedures Azienda Ospedaliero Universitaria di Sassari new
2026-08-25 NCT07783880 Investigation to Assess the Effects of Drug-COATED Balloons for Treatment of Plaques… 3W-Research Collaboration Group new
2026-08-20 NCT07776184 Multi-Component Delirium Prevention Bundle in Older Cardiac Intensive Care Unit Patients Tel Aviv Medical Center new
2026-08-20 NCT07775742 Effect of High-Intensity Interval Training Versus Home-Based Rehabilitation Program On… Kafrelsheikh University new
2026-08-18 NCT07771127 HEMOSTATİC PAD AND SANDBAG Uludag University new
2026-08-17 NCT07768020 Effect of Eye Mask Use on Sleep Quality and Delirium After CABG Surgery Munzur University new
2026-08-13 NCT07763769 Validation of the MedHub AutocathFFR Software Device for Non-Invasive Fractional Flow… Medhub Ltd. new
2026-08-13 NCT07762898 Sedentary Behavior Intervention for Older Adults With Coronary Heart Disease and Frailty Gansu University of Chinese Medicine new
2026-08-12 NCT07761624 Turkish Chronic Total Occlusion Percutaneous Coronary Intervention Registry Ahmet Seyfeddin Gürbüz new
2026-08-07 NCT07753031 Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid… Alcea new

Active trials by phase

Early Phase 1
3
Phase 1
6
Phase 1/2
4
Phase 2
22
Phase 2/3
4
Phase 3
38
Phase 4
93
Not charted: 949 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,119

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT05418556 Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting… Asan Medical Center Recruiting 2026-08-13
NCT06578234 Hyperemic mYocardial Perfusion by adEnosine at diffeRent Doses Region Skane Recruiting 2026-08-13
NCT05638867 NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI China National Center for Cardiovascular Diseases Recruiting 2026-08-11
NCT07753200 Net Clinical Benefit of Edoxaban Versus Apixaban in Patients With Atrial Fibrillation and… Samsung Medical Center Recruiting 2026-08-10
NCT04416581 Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion… Duk-Woo Park, MD Recruiting 2026-06-26
NCT04695106 Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and… Medical University of Gdansk Recruiting 2026-06-16
NCT07612774 CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS West China Hospital Recruiting 2026-06-09
NCT07572032 Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology… Kyungsub Song Recruiting 2026-06-01
NCT07614230 SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue… Junjie Yang Recruiting 2026-05-29
NCT06821191 Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching… University of Florida Recruiting 2026-05-12
NCT07225842 The Bridging Antiplatelet Therapy With Cangrelor 2 Study University of Florida Recruiting 2026-05-05
NCT07471867 Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry… Yonsei University Recruiting 2026-04-24
NCT05618353 The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial VA Office of Research and Development Recruiting 2026-04-22
NCT07511257 Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary… Instituto Nacional de Cardiologia Ignacio Chavez Recruiting 2026-04-09
NCT07476859 Effect of Intravenous Iron on Quality of Life in Older Patients With Acute Coronary… Fundación para la Investigación del Hospital Clínico de Valencia Recruiting 2026-03-24
NCT06451198 IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly… Shanghai Zhongshan Hospital Recruiting 2026-03-12
NCT07116343 Intrapleural Ropivacaine Infusion in Cardiac Surgery Saint Petersburg State University, Russia Recruiting 2026-03-10
NCT05681702 Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI University of Florida Recruiting 2026-03-09
NCT06916520 Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After… J.P.S Henriques Recruiting 2026-03-04
NCT06588595 The Switching Antiplatelet-9 (SWAP-9) Study University of Florida Recruiting 2026-02-25
NCT06543082 MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study CHA University Recruiting 2026-02-18
NCT04014803 Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients… Samsung Medical Center Recruiting 2026-02-09
NCT06228456 Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective… University of Florida Recruiting 2026-02-05
NCT06691191 Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors University of Florida Recruiting 2026-02-05
NCT07349875 Colchicine Treatment for Non-Flow-Limiting Coronary Plaque by Coronary CTA: A Randomized… Nanjing First Hospital, Nanjing Medical University Recruiting 2026-01-20
See all 1,119 active Coronary Artery Disease trials with filters →

Top sponsors by active trials in this area

China National Center for Cardiovascular Diseases (30) · Fundación EPIC (22) · Yonsei University (18) · Samsung Medical Center (17) · Beijing Anzhen Hospital (14) · Seung-Jung Park (14) · Assiut University (12) · Nanjing First Hospital, Nanjing Medical University (12) · Shanghai Zhongshan Hospital (10) · University of Florida (10)

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