Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients Undergoing PCI for Complex Lesion

This study is a prospective, open label, two-arm, randomized multicenter trial to evaluate the efficacy and safety of aspirin plus prasugrel as compared with aspirin plus clopidogrel in patients undergoing elective percutaneous coronary intervention with drug eluting stents for complex coronary lesions.

NCT Number	NCT04014803
Lead Sponsor	Samsung Medical Center Collaborators: Inje University Ilsan Paik Hospital, Seoul St. Mary's Hospital, Mediplex Sejong Hospital, Chonnam National University Hospital, Sejong General Hospital, Wonkwang University Hospital, Gachon University Gil Medical Center, Keimyung University Dongsan Medical Center, Chungbuk National University Hospital, Yeungnam University Hospital, Chungnam National University Hospital, Wonju Severance Christian Hospital, Konkuk University Chungju Hospital, Chung-Ang University Hospital, Dankook University, Incheon St.Mary's Hospital, Gyeongsang National University Hospital, Soonchunhyang University Hospital, Ewha Womans University Seoul Hospital
Conditions	Coronary Artery Disease
Enrollment	3,500 participants
Start Date	2020-01-13
Primary Completion	2027-06-30 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-09