Drug Pipeline

Alemtuzumab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
21
Active Studies
9
Recruiting
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-05 NCT06872333
Allo HSCT for High Risk Hemoglobinopathies		 Trial arms changed: 4 -> 5
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-01 NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Phase 2 Not Yet Recruiting
2026-05-20 NCT07599176 Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors Phase 1/2 Recruiting
Active Studies by Phase
Phase 2
8
Phase 1/2
8
Phase 1
2
Early Phase 1
1
Not specified
2
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT03579875 Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders Fanconi Anemia Recruiting
NCT03214354 Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major… Sickle Cell Disease Recruiting
NCT04339777 Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity Lymphoproliferative Disorders Recruiting
NCT06872333 Allo HSCT for High Risk Hemoglobinopathies Graft Failure Recruiting
NCT01659606 Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With… Dyskeratosis Congenita Active, Not Recruiting
NCT03821610 A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With… Acute Lymphoblastic Leukemia Active, Not Recruiting
NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Sickle Cell Disease Not Yet Recruiting
NCT06084780 Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei… Secondary Malignant Neoplasm of Retroperitoneum Not Yet Recruiting
Phase 1/2
NCT03500731 Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure Idiopathic Pulmonary Fibrosis Recruiting
NCT06959771 Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome… CD40L-HyperIgM Syndrome Recruiting
NCT05463133 Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease… Chronic Granulomatous Disease Recruiting
NCT07599176 Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors Sickle Cell Disease Recruiting
NCT05357482 Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell… Sickle Cell Anemia Active, Not Recruiting
NCT00977691 Haploidentical PBMC Transplant for Severe Congenital Anemias Sickle Cell Anemia Active, Not Recruiting
NCT03077542 Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell… Sickle Cell Disease Active, Not Recruiting
NCT02629120 High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant… Chronic Granulomatous Disease Transplant Active, Not Recruiting
Phase 1
NCT07015684 131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in… Sickling Disorder Due to Hemoglobin S Recruiting
NCT05384756 TMLI and Alemtuzumab for Treatment of Sickle Cell Disease Sickle Cell Disease Active, Not Recruiting
Early Phase 1
NCT03910452 Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using… Chronic Granulomatous Disease Active, Not Recruiting
Not specified
NCT01652092 Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune… SCID Active, Not Recruiting
NCT05688436 A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants… Multiple Sclerosis Active, Not Recruiting
Sponsors Running Alemtuzumab Trials
National Heart, Lung, and Blood Institute (NHLBI) (4) National Institute of Allergy and Infectious Diseases (NIAID) (4) Masonic Cancer Center, University of Minnesota (3) Boston Children's Hospital (1) University of Calgary (1) Paul Szabolcs (1) University of Birmingham (1) National Cancer Institute (NCI) (1) City of Hope Medical Center (1) Biogen (1)
Disease Areas
Sickle Cell Disease (8) Thalassemia (2) COPD (1) Idiopathic Pulmonary Fibrosis (1) Myelodysplastic Syndromes (MDS) (1) Leukemia (1) Acute Lymphoblastic Leukemia (ALL) (1) Multiple Sclerosis (1)
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