Disease Landscape

Idiopathic Pulmonary Fibrosis Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
189
Active Trials
100
Recruiting
21
Phase 3
128
Sponsors
22
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-14 NCT06968845
A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis · Rein Therapeutics
Trial sites expanded: 30 -> 36 locations
2026-08-13 NCT01915511
Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry · Duke University
Trial sites expanded: 44 -> 47 locations
2026-08-13 NCT07743996
Emotional and Social Experiences of Antifibrotic (AF) Therapy Among Idiopathic Pulmonary… · Boehringer Ingelheim
Recruitment opened
2026-08-12 NCT05988463
Dose-Escalation Study of Artesunate Patients With IPF · Joseph C. Wu
date change Primary completion pushed: 2027-11-01 -> 2028-11-01
2026-08-11 NCT07284459
Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With… · Contineum Therapeutics
Trial sites expanded: 60 -> 64 locations
2026-08-11 NCT07194382
AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02… · Avalyn Pharma Inc.
Trial sites expanded: 3 -> 24 locations
2026-08-09 NCT07329959
CAR-DC for End-Stage IPF · Second Affiliated Hospital, School of Medicine, Zhejiang University
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine
2026-08-09 NCT05899556
Pinpointing the Factors Affecting Clinical Study Experiences of Pulmonary Fibrosis… · Power Life Sciences Inc.
overall status: Not Yet Recruiting → Unknown
2026-08-09 NCT04304898
An International Patient-led Registry in Fibrotic Interstitial Lung Diseases Using… · Erasmus Medical Center
overall status: Recruiting → Unknown
2026-08-08 NCT06951217
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL) · Avalyn Pharma Inc.
Trial sites expanded: 54 -> 68 locations
2026-08-04 NCT07036029
NAL ER IPF Respiratory Function and Safety Study · Trevi Therapeutics
Trial completed
2026-08-04 NCT07036029
NAL ER IPF Respiratory Function and Safety Study · Trevi Therapeutics
Enrollment reduced: 10 -> 9 participants
2026-08-04 NCT07284459
Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With… · Contineum Therapeutics
Trial sites expanded: 57 -> 60 locations
2026-08-02 NCT06304207
Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease · MGH Institute of Health Professions
overall status: Recruiting → Unknown
2026-08-01 NCT06230822
Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary… · Wuhan Optics Valley Vcanbiopharma Co., Ltd.
Trial completed
2026-08-01 NCT06230822
Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary… · Wuhan Optics Valley Vcanbiopharma Co., Ltd.
date change Primary completion pushed: 2025-01 -> 2025-03-13
2026-08-01 NCT06230822
Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary… · Wuhan Optics Valley Vcanbiopharma Co., Ltd.
date change Completion moved earlier: 2026-12 -> 2025-08-01
2026-07-29 NCT04905693
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease · United Therapeutics
date change Primary completion pushed: 2026-06 -> 2029-12
2026-07-29 NCT04905693
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease · United Therapeutics
date change Completion pushed: 2026-06 -> 2029-12
2026-07-24 NCT06968845
A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis · Rein Therapeutics
Trial sites expanded: 21 -> 30 locations
Showing 20 of 22 changes detected in the last 30 days.
New Sponsor Entrants, Last 90 Days
First PostedTrialSponsorPhase
2026-08-12 NCT07761377 Retrospective Validation of AccuPulmo CT Portal for Detecting Pulmonary Fibrosis on Chest… Taichung Veterans General Hospital NEW
2026-07-22 NCT07719023 A Phase 3 Study of Efficacy and Safety of AK3280 in Patients With Idiopathic Pulmonary… Shanghai Ark Biopharmaceutical Co., Ltd. NEW Phase 3
2026-07-16 NCT07707245 Identification of Diagnostic and Prognostic Biomarkers in the Pathological Continuum of… Fondazione Don Carlo Gnocchi ETS NEW
2026-07-07 NCT07687459 Study Evaluation Rentosertib (INS018_055) Administered Orally in Patients With Idiopathic… InSilico Medicine Hong Kong Limited NEW Phase 3
2026-07-07 NCT07686562 Artificial Intelligence (AI) Detection of Incidental Interstitial Opacity on Chest… Chung-Ang University Hospital NEW
2026-07-06 NCT07683728 A Prospective, Multi-Center Registry Study of Progressive Pulmonary Fibrosis (PPF) in… Zuojun Xu NEW
2026-07-02 NCT07682337 Study of Single and Multiple Oral Doses of SCB0020160 in Healthy Adult Male Subjects SCBIO Inc. NEW Phase 1
2026-06-29 NCT07673237 Remote Evaluation and Surveillance of Patients With Interstitial Lung Disease… University of California, San Francisco NEW
2026-06-17 NCT07652658 A Phase IIb Study to Evaluate AZD8965 in Participants With IPF. AstraZeneca NEW Phase 2
2026-05-29 NCT07613216 A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects… Cosmos Rx, Inc NEW
Active Trials by Phase
Phase 4
1
Phase 3
19
Phase 2/3
2
Phase 2
42
Phase 1/2
3
Phase 1
18
Early Phase 1
5
Not specified
99
Active Trials — top 25 of 189
NCT IDTitleSponsorStatus
Phase 4
NCT07570888 This is a Trial Designed to Evaluate the Combination of Nerandomilast With Mycophenolate… University of British Columbia Not Yet Recruiting
Phase 3
NCT04965298 Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole Norfolk and Norwich University Hospitals NHS Foundation Trust Recruiting
NCT05674994 Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic… Fondation Hôpital Saint-Joseph Recruiting
NCT07464912 A Adaptive Design Clinical Trial to Evaluate the Efficacy and Safety of TDI01 Suspension… Beijing Tide Pharmaceutical Co., Ltd Recruiting
NCT07299695 Intravenous Immunoglobulin for the Treatment of Acute Exacerbations of Idiopathic… Argyrios Tzouvelekis Recruiting
NCT07082842 Confirmatory Clinical Study of HEC585 Tablets in Patients With IPF Sunshine Lake Pharma Co., Ltd. Recruiting
NCT07671911 Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine… Trevi Therapeutics Recruiting
NCT05943535 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive… United Therapeutics Recruiting
NCT07284602 Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to… PureTech Recruiting
NCT06238622 A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary… Boehringer Ingelheim Recruiting
NCT07201922 A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People… Boehringer Ingelheim Recruiting
NCT06003426 A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants… Bristol-Myers Squibb Active, Not Recruiting
NCT07503587 Evaluating the Efficacy and Safety of of HSK44459 in People With Progressive Pulmonary… Haisco Pharmaceutical Group Co., Ltd. Not Yet Recruiting
NCT07519070 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate… Haisco Pharmaceutical Group Co., Ltd. Not Yet Recruiting
NCT07520110 Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis University of Massachusetts, Worcester Not Yet Recruiting
NCT06025578 A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants… Bristol-Myers Squibb Active, Not Recruiting
NCT07687459 Study Evaluation Rentosertib (INS018_055) Administered Orally in Patients With Idiopathic… InSilico Medicine Hong Kong Limited Not Yet Recruiting
NCT07719023 A Phase 3 Study of Efficacy and Safety of AK3280 in Patients With Idiopathic Pulmonary… Shanghai Ark Biopharmaceutical Co., Ltd. Not Yet Recruiting
NCT04905693 Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease United Therapeutics Enrolling by Invitation
NCT07441408 Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in… Bristol-Myers Squibb Not Yet Recruiting
Phase 2/3
NCT06125327 SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis… Guangzhou JOYO Pharma Co., Ltd Recruiting
NCT04948203 Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of… University of Chicago Active, Not Recruiting
Phase 2
NCT06189820 Role of the Fibroblast Activation Protein (FAP) as Biomarker of Fibrotic Lung Diseases Erasme University Hospital Recruiting
NCT06567717 Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis Cedars-Sinai Medical Center Recruiting
NCT05975983 Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary… InSilico Medicine Hong Kong Limited Recruiting
See all 189 active Idiopathic Pulmonary Fibrosis trials with filters →
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