Screening for Cardiac and Cardiac-associated Pathology Using Single-channel Electrocardiogram

It is a prospective, controlled, single-center, observational, non-randomized study. The study is planned to include at least 4000 patients 18 years old and older in the training sample and 1000 patients over 18 years old in the test sample (the total number of patients is at least 5000 people). Patients will be included in the study if they have undergone a full examination (laboratory, clinical and instrumental), allowing for the verification or exclusion of cardiac and cardiac-associated pathology in accordance with current recommendations. During the course of the study, the authors of the work do not interfere with the above-mentioned scope of the examination, which is carried out on patients in accordance with clinical guidelines. All patients included in the study will undergo ECG recording in standard lead I for 1 minute twice, followed by spectral analysis of the obtained data, which will be stored at the remote monitoring center of Sechenov University without being linked to the personal data of patients. A spectral analysis of the electrocardiogram will be performed using a continuous wavelet transform. The result of this study will be the identification of ECG parameters that will correlate with cardiac and cardiac-associated pathology

NCT Number	NCT07396792
Lead Sponsor	I.M. Sechenov First Moscow State Medical University
Conditions	Arterial Hypertension, Heart Rhythm Disorders, Valvular Heart Diseases, Heart Failure, Diabetes Mellitus, Chronic Kidney Disease (Stage 3-4), Metabolic Syndrome, Coronary Artery Disease
Enrollment	4,000 participants
Start Date	2026-04-01
Primary Completion	2028-03-01 (estimated)
Study Completion	2028-05-13 (estimated)
Updated on ClinicalTrials.gov	2026-04-16