Sponsor Pipeline

UNC Lineberger Comprehensive Cancer Center Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
88
Active Trials
52
Recruiting
10
Disease Areas
7
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT07116837
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-12 NCT07116837
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
Enrollment reduced: 3500 -> 3113 participants
2026-06-12 NCT07116837
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
date change Primary completion moved earlier: 2026-07-18 -> 2026-06-14
2026-06-12 NCT07116837
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
date change Completion moved earlier: 2026-07-18 -> 2026-06-14
2026-05-29 NCT07428330
Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in…
date change Completion pushed: 2027-09 -> 2028-03
2026-05-23 NCT07428330
Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in…
Enrollment increased: 2912 -> 7597 participants
2026-05-21 NCT06411756
Physical Activity Centers Empowerment
Trial completed
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-10 NCT07639242 Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or… Phase 2 Not Yet Recruiting
2026-06-09 NCT07634653 Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic… Not Yet Recruiting
2026-06-05 NCT07630168 Effects of Infusion Timing on Treatment Response in Solid Tumors Phase 2 Not Yet Recruiting
2026-06-03 NCT07624123 Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in… Not Yet Recruiting
2026-05-26 NCT07605949 Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML Phase 2 Not Yet Recruiting
2026-05-20 NCT07599462 Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes Recruiting
2026-05-15 NCT07588607 Social Media Posts About Cancer: Five Timepoints Completed
Active Trials by Phase
Phase 2
22
Phase 1/2
4
Phase 1
11
Early Phase 1
3
Not specified
48
Active Trials — top 25 of 88
NCT IDTitleConditionStatus
Phase 2
NCT03977233 Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer Pancreatic Ductal Adenocarcinoma (PDAC) Recruiting
NCT07278557 Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia Head and Neck Cancer Recruiting
NCT05578326 Study of Trilaciclib and Lurbinectidin Lung Cancer Recruiting
NCT06902311 Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous… Breast Cancer Recruiting
NCT07069595 PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease Breast Cancer Recruiting
NCT07276880 Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion… Breast Cancer Recruiting
NCT06727773 Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of… Breast Cancer Recruiting
NCT07340541 Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies Breast Cancer Recruiting
NCT05472792 Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation… Breast Cancer Recruiting
NCT05145400 Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma Multiple Myeloma Recruiting
NCT07225114 Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging Breast Cancer Recruiting
NCT05366166 Pembrolizumab Plus Olaparib in LA-HNSCC Squamous Cell Carcinoma of Head and Neck Active, Not Recruiting
NCT03174275 Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and… Carcinoma, Squamous Cell Active, Not Recruiting
NCT07484139 H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in… Oral Cavity Squamous Cell Carcinoma Not Yet Recruiting
NCT07545746 Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treatment Outcomes in… HIV Infections Not Yet Recruiting
NCT07078838 Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1… Endometrial Cancer Not Yet Recruiting
NCT07630168 Effects of Infusion Timing on Treatment Response in Solid Tumors Lung Cancer Not Yet Recruiting
NCT07526597 Study on Treatment Outcome Patterns for Patients With CLL After Discontinuation of BTK… Chronic Lymphocytic Leukemia Not Yet Recruiting
NCT05911321 Isa-Pom-Dex in Elderly/Frail Subjects With RRMM Multiple Myeloma Active, Not Recruiting
NCT07605949 Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML Leukemia Acute Myeloid Not Yet Recruiting
NCT04548648 A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas Central Nervous System Lymphoma Active, Not Recruiting
NCT07639242 Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or… Lung Cancer Not Yet Recruiting
Phase 1/2
NCT06096038 Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC Head and Neck Cancer Recruiting
NCT06483555 Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel Pancreatic Adenocarcinoma Recruiting
NCT04700527 The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized… Toxicity Recruiting
View all 88 active UNC Lineberger Comprehensive Cancer Center trials with filters →
Disease Areas
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