Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Participants will include adolescents aged 13-17 and young adults aged 18-20 who live in the US and who are susceptible to vaping or who currently vape. In an online survey, participants will be randomized to view five randomly selected vaping prevention ads identified from a previous content analysis. After viewing the videos, participants will rate each video on the perceived message effectiveness scale and respond to questions about vaping appeal and urge to vape. The survey will take 15-20 minutes. A follow-up survey of a subset of participants will be conducted around two weeks after they have been exposed to vaping prevention video ads in the baseline survey. Participants will view a total of six videos, including the five videos they watched previously, shown one at a time, along with one "decoy" video ad. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The survey will take 10-15 minutes.

NCT Number	NCT07116837
Lead Sponsor	UNC Lineberger Comprehensive Cancer Center Collaborators: National Institute on Drug Abuse (NIDA), Food and Drug Administration (FDA)
Conditions	Vaping
Enrollment	3,113 participants
Start Date	2025-10-01
Primary Completion	2026-06-14 (estimated)
Study Completion	2026-06-14 (estimated)
Updated on ClinicalTrials.gov	2026-07-01