UNC Lineberger Comprehensive Cancer Center clinical trial pipeline

10 trials changed in the last 30 days: 1 stopped, 5 with notable changes, 4 with minor changes only.

1. Stopped

   Digital Art Therapy for Young Cancer Survivors

   Trial terminated

   Sponsor's reason: Funding unavailable

   Also in this update: Final enrollment: 2 participants (planned 15); Primary completion date changed from estimate of Apr 2027 to Aug 28, 2026

   UNC Lineberger Comprehensive Cancer Center·Not applicable· NCT06789666· Registry history of NCT06789666 on ClinicalTrials.gov (opens the registry)

   Updated Oct 15, 2026

2. Notable

   Urine HPV Testing for Cervical Cancer Screening · HIV in South…Urine HPV Testing for Cervical Cancer Screening · HIV in South Africa

   Primary and study completion pushed from Aug 2026 to Aug 2027

   UNC Lineberger Comprehensive Cancer Center·Not applicable· NCT05413798· Registry history of NCT05413798 on ClinicalTrials.gov (opens the registry)

   Updated Sep 30, 2026

3. Notable

   Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory…Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC

   Primary endpoint(s) modified

   Also in this update: Primary completion pushed from Sep 1, 2026 to Oct 1, 2026

   UNC Lineberger Comprehensive Cancer Center·Phase 1· NCT06096038· Registry history of NCT06096038 on ClinicalTrials.gov (opens the registry)

   Updated Sep 16, 2026

4. Notable

   NeoAdjuvant, Spare-Adjuvant (NASA) in Stage IIIB-IV (M1a)…NeoAdjuvant, Spare-Adjuvant (NASA) in Stage IIIB-IV (M1a) Melanoma

   Recruitment opened

   UNC Lineberger Comprehensive Cancer Center·Phase 2· NCT07740941· Registry history of NCT07740941 on ClinicalTrials.gov (opens the registry)

   Updated Sep 30, 2026

5. Notable

   Pharmacologic Therapies to Mitigate Radiation- Associated Heart…Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

   Recruitment opened

   UNC Lineberger Comprehensive Cancer Center·Phase 2· NCT07685938· Registry history of NCT07685938 on ClinicalTrials.gov (opens the registry)

   Updated Sep 17, 2026

6. Notable

   Keep Social Randomized Controlled Trial for Young · Cancer

   Start date pushed from Sep 15, 2026 to Oct 15, 2026

   Also in this update: Trial status changed: Enrolling by Invitation → Not Yet Recruiting; and 3 more changes in the last 30 days

   UNC Lineberger Comprehensive Cancer Center·Not applicable· NCT07788339· Registry history of NCT07788339 on ClinicalTrials.gov (opens the registry)

   Updated Sep 23, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.